Staff View: Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf

Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf

Zirconium oxide nanoparticles (ZrO2 NPs) were synthesized with an effective capping agent using aqueous extract of Chlorentus erectus at the optimized conditions. The aqueous leaf extract contained phytochemical compounds that could regulate the size and shape of the nanoparticles. The average size...

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Main Authors:	Hasan, Nor' Aishah, Wazir, Nurul Natasha, Zainal-Abidin, Nurhamimah, Nawahwi, Mohd Zaini, Badrol Hisham, Nurul Atikah, Yasin, Yamin, Nik Masdek, Nik Rozlin, Khairat, Jasmine Elanie, Yu, Lim Z.H.I., Mohamad Azzeme, Azzreena, Arief, Syukri, Putri, Gusliani E.K.A., Ahmad, Nor Monica
Format:	Article
Language:	English
Published:	Asian Publication Corporation 2024
Online Access:	http://psasir.upm.edu.my/id/eprint/113585/1/113585.pdf http://psasir.upm.edu.my/id/eprint/113585/ https://asianpubs.org/index.php/ajchem/article/view/36_7_30
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spelling	my.upm.eprints.1135852024-11-14T04:01:22Z http://psasir.upm.edu.my/id/eprint/113585/ Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf Hasan, Nor' Aishah Wazir, Nurul Natasha Zainal-Abidin, Nurhamimah Nawahwi, Mohd Zaini Badrol Hisham, Nurul Atikah Yasin, Yamin Nik Masdek, Nik Rozlin Khairat, Jasmine Elanie Yu, Lim Z.H.I. Mohamad Azzeme, Azzreena Arief, Syukri Putri, Gusliani E.K.A. Ahmad, Nor Monica Zirconium oxide nanoparticles (ZrO2 NPs) were synthesized with an effective capping agent using aqueous extract of Chlorentus erectus at the optimized conditions. The aqueous leaf extract contained phytochemical compounds that could regulate the size and shape of the nanoparticles. The average size of C. erectus-ZrO2 NPs crystallite was 10.42 nm, which was determined based on Scherrer Debye’s equation. The finding indicated the effectiveness of the phytochemical compounds to diminish the agglomeration of the particles. The C. erectus mediated ZrO2 NPs were in spherical clusters when observed through a transmission electron microscope (TEM). An elemental energy diffraction X-ray (EDX) assessment also revealed a significant zirconium and oxygen percentage, suggesting that the phytochemicals present in the leaf extract did not alter the purity of C. erectus-ZrO2 NPs. Moreover, 200 µg/mL of synthesized ZrO2 NPs effectively inhibited K. pneumoniae. Up to 300 µg/mL of C. erectus- ZrO2 NPs demonstrated non-toxicity to vero cells and low antiviral properties against the DENV-2 virus when introduced to cells post-infection. Asian Publication Corporation 2024 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/113585/1/113585.pdf Hasan, Nor' Aishah and Wazir, Nurul Natasha and Zainal-Abidin, Nurhamimah and Nawahwi, Mohd Zaini and Badrol Hisham, Nurul Atikah and Yasin, Yamin and Nik Masdek, Nik Rozlin and Khairat, Jasmine Elanie and Yu, Lim Z.H.I. and Mohamad Azzeme, Azzreena and Arief, Syukri and Putri, Gusliani E.K.A. and Ahmad, Nor Monica (2024) Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf. Asian Journal of Chemistry, 36 (7). pp. 1705-1712. ISSN 0970-7077; eISSN: 0970-7077 https://asianpubs.org/index.php/ajchem/article/view/36_7_30 10.14233/ajchem.2024.31775
institution	Universiti Putra Malaysia
building	UPM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Putra Malaysia
content_source	UPM Institutional Repository
url_provider	http://psasir.upm.edu.my/
language	English
description	Zirconium oxide nanoparticles (ZrO2 NPs) were synthesized with an effective capping agent using aqueous extract of Chlorentus erectus at the optimized conditions. The aqueous leaf extract contained phytochemical compounds that could regulate the size and shape of the nanoparticles. The average size of C. erectus-ZrO2 NPs crystallite was 10.42 nm, which was determined based on Scherrer Debye’s equation. The finding indicated the effectiveness of the phytochemical compounds to diminish the agglomeration of the particles. The C. erectus mediated ZrO2 NPs were in spherical clusters when observed through a transmission electron microscope (TEM). An elemental energy diffraction X-ray (EDX) assessment also revealed a significant zirconium and oxygen percentage, suggesting that the phytochemicals present in the leaf extract did not alter the purity of C. erectus-ZrO2 NPs. Moreover, 200 µg/mL of synthesized ZrO2 NPs effectively inhibited K. pneumoniae. Up to 300 µg/mL of C. erectus- ZrO2 NPs demonstrated non-toxicity to vero cells and low antiviral properties against the DENV-2 virus when introduced to cells post-infection.
format	Article
author	Hasan, Nor' Aishah Wazir, Nurul Natasha Zainal-Abidin, Nurhamimah Nawahwi, Mohd Zaini Badrol Hisham, Nurul Atikah Yasin, Yamin Nik Masdek, Nik Rozlin Khairat, Jasmine Elanie Yu, Lim Z.H.I. Mohamad Azzeme, Azzreena Arief, Syukri Putri, Gusliani E.K.A. Ahmad, Nor Monica
spellingShingle	Hasan, Nor' Aishah Wazir, Nurul Natasha Zainal-Abidin, Nurhamimah Nawahwi, Mohd Zaini Badrol Hisham, Nurul Atikah Yasin, Yamin Nik Masdek, Nik Rozlin Khairat, Jasmine Elanie Yu, Lim Z.H.I. Mohamad Azzeme, Azzreena Arief, Syukri Putri, Gusliani E.K.A. Ahmad, Nor Monica Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf
author_facet	Hasan, Nor' Aishah Wazir, Nurul Natasha Zainal-Abidin, Nurhamimah Nawahwi, Mohd Zaini Badrol Hisham, Nurul Atikah Yasin, Yamin Nik Masdek, Nik Rozlin Khairat, Jasmine Elanie Yu, Lim Z.H.I. Mohamad Azzeme, Azzreena Arief, Syukri Putri, Gusliani E.K.A. Ahmad, Nor Monica
author_sort	Hasan, Nor' Aishah
title	Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf
title_short	Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf
title_full	Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf
title_fullStr	Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf
title_full_unstemmed	Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf
title_sort	antibacterial and antiviral potential of zirconium oxide nanoparticle using extract of chloranthus erectus leaf
publisher	Asian Publication Corporation
publishDate	2024
url	http://psasir.upm.edu.my/id/eprint/113585/1/113585.pdf http://psasir.upm.edu.my/id/eprint/113585/ https://asianpubs.org/index.php/ajchem/article/view/36_7_30
_version_	1816132747966545920
score	13.222552

Antibacterial and antiviral potential of Zirconium Oxide nanoparticle using extract of Chloranthus Erectus leaf

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