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Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities

Twenty-six water-soluble extracts from eighteen local medicinal plant specirs and fourteen methanol extracts from ten medicinal plants were screened in order to find new immunomodulating substances from those medicinal plants. Effects on lymphocyte proliferation and macrophage function in host de...

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Main Author: Samat, Nor Azura
Format: Thesis
Language:English
English
Published: 2003
Online Access:http://psasir.upm.edu.my/id/eprint/11249/1/FPSK_M_2003_6.pdf
http://psasir.upm.edu.my/id/eprint/11249/
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spelling my.upm.eprints.112492024-06-13T01:48:43Z http://psasir.upm.edu.my/id/eprint/11249/ Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities Samat, Nor Azura Twenty-six water-soluble extracts from eighteen local medicinal plant specirs and fourteen methanol extracts from ten medicinal plants were screened in order to find new immunomodulating substances from those medicinal plants. Effects on lymphocyte proliferation and macrophage function in host defense mechanism including the nitric oxide (NO) production, phagocytic activity and intracellular killing ability were tested. Lymphocyte or macrophage was treated with those extracts at the concentration of 2.5 - 50J..lg/ ml. Four of the water-soluble extracts shows mitogenicity where it causes highest mitogenicity at different concentrations. Both methanol and water-soluble extracts failed to alter or improve macrophage function neither of its phagocytic activity nor its intracellular killing ability. The water extracts of S. torvum (stem bark), C. asiatica, S. grandiflora, U. lobata (stem bark) and G. vulgaris (leaves) produce NO significantly. Apart from that, haemolyti c activity was also determined. 2003-09 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11249/1/FPSK_M_2003_6.pdf Samat, Nor Azura (2003) Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities. Masters thesis, Universiti Putra Malaysia. English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description Twenty-six water-soluble extracts from eighteen local medicinal plant specirs and fourteen methanol extracts from ten medicinal plants were screened in order to find new immunomodulating substances from those medicinal plants. Effects on lymphocyte proliferation and macrophage function in host defense mechanism including the nitric oxide (NO) production, phagocytic activity and intracellular killing ability were tested. Lymphocyte or macrophage was treated with those extracts at the concentration of 2.5 - 50J..lg/ ml. Four of the water-soluble extracts shows mitogenicity where it causes highest mitogenicity at different concentrations. Both methanol and water-soluble extracts failed to alter or improve macrophage function neither of its phagocytic activity nor its intracellular killing ability. The water extracts of S. torvum (stem bark), C. asiatica, S. grandiflora, U. lobata (stem bark) and G. vulgaris (leaves) produce NO significantly. Apart from that, haemolyti c activity was also determined.
format Thesis
author Samat, Nor Azura
spellingShingle Samat, Nor Azura
Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities
author_facet Samat, Nor Azura
author_sort Samat, Nor Azura
title Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities
title_short Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities
title_full Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities
title_fullStr Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities
title_full_unstemmed Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities
title_sort screening of malaysian medicinal plants for immunomodulatory and haemolytic activities
publishDate 2003
url http://psasir.upm.edu.my/id/eprint/11249/1/FPSK_M_2003_6.pdf
http://psasir.upm.edu.my/id/eprint/11249/
_version_ 1802978771821658112
score 13.211869

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