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A cost analysis of COVID-19 vaccination: a comparison between mRNA-based and inactivated virus vaccines

Introduction: COVID-19 vaccination is considered a primary preventive measure to combat the COVID-19 pandemic. Several types of COVID-19 vaccines were developed, among them the mRNA-based vaccine and the inactivated virus vaccine. Different COVID-19 vaccines have different purchase price and require...

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Main Authors: Samsudin, Khalsom, Mahmud, Aidalina, Ahmad, Norliza
Format: Article
Language:English
Published: Universiti Putra Malaysia Press 2024
Online Access:http://psasir.upm.edu.my/id/eprint/112190/1/2024032615323329_MJMHS_0666.pdf
http://psasir.upm.edu.my/id/eprint/112190/
https://medic.upm.edu.my/upload/dokumen/2024032615323329_MJMHS_0666.pdf
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spelling my.upm.eprints.1121902024-09-25T01:39:11Z http://psasir.upm.edu.my/id/eprint/112190/ A cost analysis of COVID-19 vaccination: a comparison between mRNA-based and inactivated virus vaccines Samsudin, Khalsom Mahmud, Aidalina Ahmad, Norliza Introduction: COVID-19 vaccination is considered a primary preventive measure to combat the COVID-19 pandemic. Several types of COVID-19 vaccines were developed, among them the mRNA-based vaccine and the inactivated virus vaccine. Different COVID-19 vaccines have different purchase price and require different logistics system, which translate into different estimated vaccination costs. Therefore, this study aims to estimate the cost of COVID-19 vaccination using the mRNA-based vaccine compared to the inactivated virus vaccine to assist future decision-making related to COVID-19 vaccination. Methods: Direct costs for per-dose vaccination for both vaccines were estimated from the health provider’s perspective using the microcosting approach. Vaccination pathways were constructed for both the mRNA-based and the inactivated virus vaccine based on activities involving the acquisition, transportation, storage, and vaccine injection processes. Cost value was obtained from purchase documents, asset records, and market surveys. Results: The estimated costs for COVID-19 vaccination were RM 69.71 per dose for the mRNA-based vaccine and RM 91.68 per dose for the inactivated virus vaccine. The difference in estimated vaccination costs was mainly driven by the difference in the vaccine purchase costs which was higher for the inactivated virus vaccine. Conclusion: COVID-19 vaccination using the mRNA-based vaccine incur was estimated to incur lower total costs to the health provider compared to the inactivated virus vaccine during the pandemic. Universiti Putra Malaysia Press 2024 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/112190/1/2024032615323329_MJMHS_0666.pdf Samsudin, Khalsom and Mahmud, Aidalina and Ahmad, Norliza (2024) A cost analysis of COVID-19 vaccination: a comparison between mRNA-based and inactivated virus vaccines. Malaysian Journal of Medicine and Health Sciences, 20 (2). pp. 226-233. ISSN 1675-8544; EISSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2024032615323329_MJMHS_0666.pdf 10.47836/mjmhs.20.2.30
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Introduction: COVID-19 vaccination is considered a primary preventive measure to combat the COVID-19 pandemic. Several types of COVID-19 vaccines were developed, among them the mRNA-based vaccine and the inactivated virus vaccine. Different COVID-19 vaccines have different purchase price and require different logistics system, which translate into different estimated vaccination costs. Therefore, this study aims to estimate the cost of COVID-19 vaccination using the mRNA-based vaccine compared to the inactivated virus vaccine to assist future decision-making related to COVID-19 vaccination. Methods: Direct costs for per-dose vaccination for both vaccines were estimated from the health provider’s perspective using the microcosting approach. Vaccination pathways were constructed for both the mRNA-based and the inactivated virus vaccine based on activities involving the acquisition, transportation, storage, and vaccine injection processes. Cost value was obtained from purchase documents, asset records, and market surveys. Results: The estimated costs for COVID-19 vaccination were RM 69.71 per dose for the mRNA-based vaccine and RM 91.68 per dose for the inactivated virus vaccine. The difference in estimated vaccination costs was mainly driven by the difference in the vaccine purchase costs which was higher for the inactivated virus vaccine. Conclusion: COVID-19 vaccination using the mRNA-based vaccine incur was estimated to incur lower total costs to the health provider compared to the inactivated virus vaccine during the pandemic.
format Article
author Samsudin, Khalsom
Mahmud, Aidalina
Ahmad, Norliza
spellingShingle Samsudin, Khalsom
Mahmud, Aidalina
Ahmad, Norliza
A cost analysis of COVID-19 vaccination: a comparison between mRNA-based and inactivated virus vaccines
author_facet Samsudin, Khalsom
Mahmud, Aidalina
Ahmad, Norliza
author_sort Samsudin, Khalsom
title A cost analysis of COVID-19 vaccination: a comparison between mRNA-based and inactivated virus vaccines
title_short A cost analysis of COVID-19 vaccination: a comparison between mRNA-based and inactivated virus vaccines
title_full A cost analysis of COVID-19 vaccination: a comparison between mRNA-based and inactivated virus vaccines
title_fullStr A cost analysis of COVID-19 vaccination: a comparison between mRNA-based and inactivated virus vaccines
title_full_unstemmed A cost analysis of COVID-19 vaccination: a comparison between mRNA-based and inactivated virus vaccines
title_sort cost analysis of covid-19 vaccination: a comparison between mrna-based and inactivated virus vaccines
publisher Universiti Putra Malaysia Press
publishDate 2024
url http://psasir.upm.edu.my/id/eprint/112190/1/2024032615323329_MJMHS_0666.pdf
http://psasir.upm.edu.my/id/eprint/112190/
https://medic.upm.edu.my/upload/dokumen/2024032615323329_MJMHS_0666.pdf
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score 13.211869

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