Staff View: Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost

Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost

The global aquaculture boom, fuelled by a reduction in wild population and detection of novel viruses, has created a demanding market, hence, there is a pressing need to investigate the immune system of fish, further. As the most diverse community of vertebrates and a central contributor to the prog...

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Main Authors:	Haridevamuthu, B., Guru, Ajay, Velayutham, Manikandan, P., Snega Priya, Arshad, Aziz, Arockiaraj, Jesu
Format:	Article
Published:	Wiley 2023
Online Access:	http://psasir.upm.edu.my/id/eprint/108999/ https://onlinelibrary.wiley.com/doi/10.1111/raq.12709
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id	my.upm.eprints.108999
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spelling	my.upm.eprints.1089992024-10-14T04:25:59Z http://psasir.upm.edu.my/id/eprint/108999/ Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost Haridevamuthu, B. Guru, Ajay Velayutham, Manikandan P., Snega Priya Arshad, Aziz Arockiaraj, Jesu The global aquaculture boom, fuelled by a reduction in wild population and detection of novel viruses, has created a demanding market, hence, there is a pressing need to investigate the immune system of fish, further. As the most diverse community of vertebrates and a central contributor to the progressing global aquaculture market, teleost continues to draw vast scientific interest. Recent breakthroughs in multi-omics technologies have provided a platform to understand the role of long non-coding RNA (lncRNA) in the host immune system during infection. Emerging evidence shows that teleost lncRNA might have a regulatory role in immune responses, mostly through lncRNA–microRNA (miRNA) sponging. Teleost lncRNA shares a functionally active short sequence complement to target the miRNA which is conserved among the several fish species. Recent report suggests that rhabdovirus exploits a lncRNA in teleost and, to dodge the host immune mechanism and negatively regulate the immune system. This observation reveals the essentiality of lncRNA in pathogen-driven immunity in teleost. Reports available on the function of teleost lncRNA are still in early stages and experimental verifications are a limiting factor. Unravelling the lncRNA-mediated immune regulation in fishes could be used against the invading pathogens to strengthen the aquaculture production. This review elaborates on the experimentally identified and functionally characterized lncRNA and its regulatory role in the teleost immune response during infection and pathogen-driven host immune evolution, which could eventually lead to achieving high standards in aquaculture productivity. Wiley 2023-01 Article PeerReviewed Haridevamuthu, B. and Guru, Ajay and Velayutham, Manikandan and P., Snega Priya and Arshad, Aziz and Arockiaraj, Jesu (2023) Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost. Reviews in Aquaculture, 15 (1). pp. 163-178. ISSN 1753-5123; ESSN: 1753-5131 https://onlinelibrary.wiley.com/doi/10.1111/raq.12709 10.1111/raq.12709
institution	Universiti Putra Malaysia
building	UPM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Putra Malaysia
content_source	UPM Institutional Repository
url_provider	http://psasir.upm.edu.my/
description	The global aquaculture boom, fuelled by a reduction in wild population and detection of novel viruses, has created a demanding market, hence, there is a pressing need to investigate the immune system of fish, further. As the most diverse community of vertebrates and a central contributor to the progressing global aquaculture market, teleost continues to draw vast scientific interest. Recent breakthroughs in multi-omics technologies have provided a platform to understand the role of long non-coding RNA (lncRNA) in the host immune system during infection. Emerging evidence shows that teleost lncRNA might have a regulatory role in immune responses, mostly through lncRNA–microRNA (miRNA) sponging. Teleost lncRNA shares a functionally active short sequence complement to target the miRNA which is conserved among the several fish species. Recent report suggests that rhabdovirus exploits a lncRNA in teleost and, to dodge the host immune mechanism and negatively regulate the immune system. This observation reveals the essentiality of lncRNA in pathogen-driven immunity in teleost. Reports available on the function of teleost lncRNA are still in early stages and experimental verifications are a limiting factor. Unravelling the lncRNA-mediated immune regulation in fishes could be used against the invading pathogens to strengthen the aquaculture production. This review elaborates on the experimentally identified and functionally characterized lncRNA and its regulatory role in the teleost immune response during infection and pathogen-driven host immune evolution, which could eventually lead to achieving high standards in aquaculture productivity.
format	Article
author	Haridevamuthu, B. Guru, Ajay Velayutham, Manikandan P., Snega Priya Arshad, Aziz Arockiaraj, Jesu
spellingShingle	Haridevamuthu, B. Guru, Ajay Velayutham, Manikandan P., Snega Priya Arshad, Aziz Arockiaraj, Jesu Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost
author_facet	Haridevamuthu, B. Guru, Ajay Velayutham, Manikandan P., Snega Priya Arshad, Aziz Arockiaraj, Jesu
author_sort	Haridevamuthu, B.
title	Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost
title_short	Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost
title_full	Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost
title_fullStr	Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost
title_full_unstemmed	Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost
title_sort	long non-coding rna, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost
publisher	Wiley
publishDate	2023
url	http://psasir.upm.edu.my/id/eprint/108999/ https://onlinelibrary.wiley.com/doi/10.1111/raq.12709
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score	13.211869

Long non-coding RNA, a supreme post-transcriptional immune regulator of bacterial or virus-driven immune evolution in teleost

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