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The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude

The episode of prolonged exposure to high altitude can cause hypoxia and potential significant health consequences. In people with high altitude disorder, the body reaction to high altitudes starts with the formation of a protein called hypoxia-inducible factor (HIF), which triggers a series of othe...

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Main Authors: Shaharuddin, Shazreen, Nik Abd Rahman, Nik Mohd Afizan, Masarudin, Mas Jaffri, N Alamassi, Mohammedarfat
Format: Article
Language:English
Published: MedCrave Group 2023
Online Access:http://psasir.upm.edu.my/id/eprint/108978/1/The%20importance%20of%20hypoxia%20sensors%20in%20detecting%20HIF-1%20biomarker%20at%20high%20altitude.pdf
http://psasir.upm.edu.my/id/eprint/108978/
https://medcraveonline.com/AAOAJ/the-importance-of-hypoxia-sensors-in-detectinghif-1-biomarker-at-high-altitude.html
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id my.upm.eprints.108978
record_format eprints
spelling my.upm.eprints.1089782024-10-17T03:36:31Z http://psasir.upm.edu.my/id/eprint/108978/ The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude Shaharuddin, Shazreen Nik Abd Rahman, Nik Mohd Afizan Masarudin, Mas Jaffri N Alamassi, Mohammedarfat The episode of prolonged exposure to high altitude can cause hypoxia and potential significant health consequences. In people with high altitude disorder, the body reaction to high altitudes starts with the formation of a protein called hypoxia-inducible factor (HIF), which triggers a series of other physiological changes and plays a central role in the hypoxia response; its activity is regulated by the oxygen-dependent degradation of the HIF-1α protein. This deserving condition provides an opportunity to study the effect of low oxygen tension of flying at high altitude that could lead to hypoxia using hypoxia sensor. MedCrave Group 2023-10-19 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/108978/1/The%20importance%20of%20hypoxia%20sensors%20in%20detecting%20HIF-1%20biomarker%20at%20high%20altitude.pdf Shaharuddin, Shazreen and Nik Abd Rahman, Nik Mohd Afizan and Masarudin, Mas Jaffri and N Alamassi, Mohammedarfat (2023) The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude. Aeronautics and Aerospace Open Access Journal, 7 (4). 132- 133. ISSN 2576-4500 https://medcraveonline.com/AAOAJ/the-importance-of-hypoxia-sensors-in-detectinghif-1-biomarker-at-high-altitude.html 10.15406/aaoaj.2023.07.00182
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description The episode of prolonged exposure to high altitude can cause hypoxia and potential significant health consequences. In people with high altitude disorder, the body reaction to high altitudes starts with the formation of a protein called hypoxia-inducible factor (HIF), which triggers a series of other physiological changes and plays a central role in the hypoxia response; its activity is regulated by the oxygen-dependent degradation of the HIF-1α protein. This deserving condition provides an opportunity to study the effect of low oxygen tension of flying at high altitude that could lead to hypoxia using hypoxia sensor.
format Article
author Shaharuddin, Shazreen
Nik Abd Rahman, Nik Mohd Afizan
Masarudin, Mas Jaffri
N Alamassi, Mohammedarfat
spellingShingle Shaharuddin, Shazreen
Nik Abd Rahman, Nik Mohd Afizan
Masarudin, Mas Jaffri
N Alamassi, Mohammedarfat
The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude
author_facet Shaharuddin, Shazreen
Nik Abd Rahman, Nik Mohd Afizan
Masarudin, Mas Jaffri
N Alamassi, Mohammedarfat
author_sort Shaharuddin, Shazreen
title The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude
title_short The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude
title_full The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude
title_fullStr The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude
title_full_unstemmed The importance of hypoxia sensors in detecting HIF-1 biomarker at high altitude
title_sort importance of hypoxia sensors in detecting hif-1 biomarker at high altitude
publisher MedCrave Group
publishDate 2023
url http://psasir.upm.edu.my/id/eprint/108978/1/The%20importance%20of%20hypoxia%20sensors%20in%20detecting%20HIF-1%20biomarker%20at%20high%20altitude.pdf
http://psasir.upm.edu.my/id/eprint/108978/
https://medcraveonline.com/AAOAJ/the-importance-of-hypoxia-sensors-in-detectinghif-1-biomarker-at-high-altitude.html
_version_ 1814054676086128640
score 13.211869

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