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In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset

Meyerozyma guilliermondii is a prospective yeast that has extensively contributed to the biotechnology sector. In 2015, M. guilliermondii strain SO which was isolated from spoiled orange has successfully been developed as an inducer-free expression system and attained a significant impact in produci...

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Main Authors: Zainudin, Robiatul Azilah, Sabri, Suriana, Salleh, Abu Bakar, Abu, Arpah, Raja Khairuddin, Raja Farhana, Oslan, Siti Nurbaya
Format: Article
Language:English
Published: SpringerOpen 2023
Online Access:http://psasir.upm.edu.my/id/eprint/108816/1/108816.pdf
http://psasir.upm.edu.my/id/eprint/108816/
https://jmhg.springeropen.com/articles/10.1186/s43042-023-00384-3
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spelling my.upm.eprints.1088162024-10-11T08:50:49Z http://psasir.upm.edu.my/id/eprint/108816/ In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset Zainudin, Robiatul Azilah Sabri, Suriana Salleh, Abu Bakar Abu, Arpah Raja Khairuddin, Raja Farhana Oslan, Siti Nurbaya Meyerozyma guilliermondii is a prospective yeast that has extensively contributed to the biotechnology sector. In 2015, M. guilliermondii strain SO which was isolated from spoiled orange has successfully been developed as an inducer-free expression system and attained a significant impact in producing industrially important recombinant proteins. The species possesses high similarity to Candida albicans which may cause candidiasis. The industrial-benefiting M. guilliermondii strain SO has been underexplored for its virulence status. Thus, this study aimed to document the potential virulence factors through the comprehensive in silico analysis of M. guilliermondii strain SO genome. This analysis demonstrated the molecular characterization which could distinguish the pathogenicity status of M. guilliermondii. SpringerOpen 2023-01-12 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/108816/1/108816.pdf Zainudin, Robiatul Azilah and Sabri, Suriana and Salleh, Abu Bakar and Abu, Arpah and Raja Khairuddin, Raja Farhana and Oslan, Siti Nurbaya (2023) In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset. Egyptian Journal of Medical Human Genetics, 24 (6). art. no. 6. pp. 1-13. ISSN 1110-8630; eISSN: 2090-2441 https://jmhg.springeropen.com/articles/10.1186/s43042-023-00384-3 10.1186/s43042-023-00384-3
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Meyerozyma guilliermondii is a prospective yeast that has extensively contributed to the biotechnology sector. In 2015, M. guilliermondii strain SO which was isolated from spoiled orange has successfully been developed as an inducer-free expression system and attained a significant impact in producing industrially important recombinant proteins. The species possesses high similarity to Candida albicans which may cause candidiasis. The industrial-benefiting M. guilliermondii strain SO has been underexplored for its virulence status. Thus, this study aimed to document the potential virulence factors through the comprehensive in silico analysis of M. guilliermondii strain SO genome. This analysis demonstrated the molecular characterization which could distinguish the pathogenicity status of M. guilliermondii.
format Article
author Zainudin, Robiatul Azilah
Sabri, Suriana
Salleh, Abu Bakar
Abu, Arpah
Raja Khairuddin, Raja Farhana
Oslan, Siti Nurbaya
spellingShingle Zainudin, Robiatul Azilah
Sabri, Suriana
Salleh, Abu Bakar
Abu, Arpah
Raja Khairuddin, Raja Farhana
Oslan, Siti Nurbaya
In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset
author_facet Zainudin, Robiatul Azilah
Sabri, Suriana
Salleh, Abu Bakar
Abu, Arpah
Raja Khairuddin, Raja Farhana
Oslan, Siti Nurbaya
author_sort Zainudin, Robiatul Azilah
title In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset
title_short In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset
title_full In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset
title_fullStr In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset
title_full_unstemmed In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset
title_sort in silico identification of prospective virulence factors associated with candidiasis in meyerozyma guilliermondii strain so from genome dataset
publisher SpringerOpen
publishDate 2023
url http://psasir.upm.edu.my/id/eprint/108816/1/108816.pdf
http://psasir.upm.edu.my/id/eprint/108816/
https://jmhg.springeropen.com/articles/10.1186/s43042-023-00384-3
_version_ 1814054669928890368
score 13.223943

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