Finding lead compounds for dengue antivirals from a collection of old drugs through in silico target prediction and subsequent in vitro validation.
Dengue virus (DENV) infection is one of the most widely spread flavivirus infections. Despite the fatality it could cause, no antiviral treatment is currently available to treat the disease. Hence, this study aimed to repurpose old drugs as novel DENV NS3 inhibitors. Ligand-based (L-B) and proteoche...
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| Main Authors: | , , , |
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| Format: | Article |
| Published: |
American Chemical Society (ACS)
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/108009/ https://pubs.acs.org/doi/suppl/10.1021/acsomega.3c02607/suppl_file/ao3c02607_si_001.pdf |
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