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Eco-sustainable production of bioactive Sialyated-Mucin (SiaMuc) glycopeptide from edible birds nest co-product

Edible bird’s nest (EBN) is the dried salivary secretion of swiftlets during the breeding season. The widely consumed EBN for its highly unique nutrients has contributed to a high demand for international exportation. However, the processing of EBN to remove inedible materials (i.e. sand, dust, feat...

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Main Authors: Tan, HuiYan, Hui, Zi Lim, Seng, Joe Lim, Babji, Abdul Salam, Sarbini, Shahrul Razid
Format: Article
Language:English
Published: Malaysian Society of Applied Biology 2023
Online Access:http://psasir.upm.edu.my/id/eprint/107438/1/107438.pdf
http://psasir.upm.edu.my/id/eprint/107438/
https://jms.mabjournal.com/index.php/mab/article/view/2910
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spelling my.upm.eprints.1074382024-11-04T02:44:11Z http://psasir.upm.edu.my/id/eprint/107438/ Eco-sustainable production of bioactive Sialyated-Mucin (SiaMuc) glycopeptide from edible birds nest co-product Tan, HuiYan Hui, Zi Lim Seng, Joe Lim Babji, Abdul Salam Sarbini, Shahrul Razid Edible bird’s nest (EBN) is the dried salivary secretion of swiftlets during the breeding season. The widely consumed EBN for its highly unique nutrients has contributed to a high demand for international exportation. However, the processing of EBN to remove inedible materials (i.e. sand, dust, feathers) has contributed to several wastes. The disposal of this waste is hazardous to the environment and a waste of value due to abundant sialylated-mucin (SiaMuc) glycoprotein attached in the impurities. This “waste” is the processing co-product of EBN. Therefore, this study aimed to recover SiaMuc-glycoprotein in EBN co-product (EBNco-P) in the form of bioactive SiaMuc-glycopeptide. Through enzymatic hydrolysis, an eco-friendly alternative to transform insoluble SiaMuc-glycoprotein in EBNco-P into soluble bioactive SiaMuc-glycopeptide, valuable nutrients are separable from the impurities. Previously, through our research, this biotechnology has been applied to cleaned EBN. The research finds that the enzymatic hydrolysis of EBN that produces EBN glycopeptide has led to bioconversion into a high-grade product with enhanced nutritional bioavailability and functionality. Similar results are also revealed in the analyses of cleaned-EBN and EBN co-products. Whereby, the result revealed that the optimum hydrolysis period was at 90 min, in which the DH and enhanced solubility indicated a complete breakdown of glycoprotein into bioactive glycopeptide. This result is in line with the physicochemical analysis result. The hydrolysis has significantly decreased (p≤0.05) the EBN protein content, while the levels for peptide, glycopeptide, polysaccharides, and sialic acid showed the opposite. This study may contribute to broadening the EBN product development in terms of nutraceutical functionality. With the availability of low-cost EBN co-products, this study is beneficial not only scientifically, but also to the consumers, commercialization, and industrialization. Malaysian Society of Applied Biology 2023-12-15 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/107438/1/107438.pdf Tan, HuiYan and Hui, Zi Lim and Seng, Joe Lim and Babji, Abdul Salam and Sarbini, Shahrul Razid (2023) Eco-sustainable production of bioactive Sialyated-Mucin (SiaMuc) glycopeptide from edible birds nest co-product. Malaysian Applied Biology, 52 (5). 55 - 63. ISSN 0126-8643; eISSN: 2462-151X https://jms.mabjournal.com/index.php/mab/article/view/2910 10.55230/mabjournal.v52i5.fisas02
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Edible bird’s nest (EBN) is the dried salivary secretion of swiftlets during the breeding season. The widely consumed EBN for its highly unique nutrients has contributed to a high demand for international exportation. However, the processing of EBN to remove inedible materials (i.e. sand, dust, feathers) has contributed to several wastes. The disposal of this waste is hazardous to the environment and a waste of value due to abundant sialylated-mucin (SiaMuc) glycoprotein attached in the impurities. This “waste” is the processing co-product of EBN. Therefore, this study aimed to recover SiaMuc-glycoprotein in EBN co-product (EBNco-P) in the form of bioactive SiaMuc-glycopeptide. Through enzymatic hydrolysis, an eco-friendly alternative to transform insoluble SiaMuc-glycoprotein in EBNco-P into soluble bioactive SiaMuc-glycopeptide, valuable nutrients are separable from the impurities. Previously, through our research, this biotechnology has been applied to cleaned EBN. The research finds that the enzymatic hydrolysis of EBN that produces EBN glycopeptide has led to bioconversion into a high-grade product with enhanced nutritional bioavailability and functionality. Similar results are also revealed in the analyses of cleaned-EBN and EBN co-products. Whereby, the result revealed that the optimum hydrolysis period was at 90 min, in which the DH and enhanced solubility indicated a complete breakdown of glycoprotein into bioactive glycopeptide. This result is in line with the physicochemical analysis result. The hydrolysis has significantly decreased (p≤0.05) the EBN protein content, while the levels for peptide, glycopeptide, polysaccharides, and sialic acid showed the opposite. This study may contribute to broadening the EBN product development in terms of nutraceutical functionality. With the availability of low-cost EBN co-products, this study is beneficial not only scientifically, but also to the consumers, commercialization, and industrialization.
format Article
author Tan, HuiYan
Hui, Zi Lim
Seng, Joe Lim
Babji, Abdul Salam
Sarbini, Shahrul Razid
spellingShingle Tan, HuiYan
Hui, Zi Lim
Seng, Joe Lim
Babji, Abdul Salam
Sarbini, Shahrul Razid
Eco-sustainable production of bioactive Sialyated-Mucin (SiaMuc) glycopeptide from edible birds nest co-product
author_facet Tan, HuiYan
Hui, Zi Lim
Seng, Joe Lim
Babji, Abdul Salam
Sarbini, Shahrul Razid
author_sort Tan, HuiYan
title Eco-sustainable production of bioactive Sialyated-Mucin (SiaMuc) glycopeptide from edible birds nest co-product
title_short Eco-sustainable production of bioactive Sialyated-Mucin (SiaMuc) glycopeptide from edible birds nest co-product
title_full Eco-sustainable production of bioactive Sialyated-Mucin (SiaMuc) glycopeptide from edible birds nest co-product
title_fullStr Eco-sustainable production of bioactive Sialyated-Mucin (SiaMuc) glycopeptide from edible birds nest co-product
title_full_unstemmed Eco-sustainable production of bioactive Sialyated-Mucin (SiaMuc) glycopeptide from edible birds nest co-product
title_sort eco-sustainable production of bioactive sialyated-mucin (siamuc) glycopeptide from edible birds nest co-product
publisher Malaysian Society of Applied Biology
publishDate 2023
url http://psasir.upm.edu.my/id/eprint/107438/1/107438.pdf
http://psasir.upm.edu.my/id/eprint/107438/
https://jms.mabjournal.com/index.php/mab/article/view/2910
_version_ 1814936557216333824
score 13.211869

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