Antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of Weissella confusa UPM22MT04
This study was aimed to produce zinc oxide nanoparticles (ZnO-NPs) using the supernatant of Weissella confusa UPM22MT04 and assess their effectiveness in inhibiting methicillin resistant Staphylococcus aureus (MRSA). An isolate of Weissella confusa UPM22MT04 was isolated from a wastewater treatment...
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University of Baghdad
2023
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my.upm.eprints.1066072024-08-09T03:45:39Z http://psasir.upm.edu.my/id/eprint/106607/ Antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of Weissella confusa UPM22MT04 Al-Tameemi, A. I. Masarudin, M. J. A. Rahim, R. Timms, V. Neilan, B. Isa, N. M. This study was aimed to produce zinc oxide nanoparticles (ZnO-NPs) using the supernatant of Weissella confusa UPM22MT04 and assess their effectiveness in inhibiting methicillin resistant Staphylococcus aureus (MRSA). An isolate of Weissella confusa UPM22MT04 was isolated from a wastewater treatment plant in Johor, Malaysia, and was utilized to synthesize ZnO-NPs. The synthesized ZnO-NPs were characterized through several techniques, including UV-visible spectroscopy, Fourier-transform infrared spectroscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, and dynamic light scattering. Monodisperse spherical ZnO-NPs of 1.7 - 7.9 nm were obtained with 0.1 M zinc nitrate at 80°C. The biosynthesized ZnO-NPs exhibited vigorous inhibitory activity against MRSA. Results found that ZnO-NPs inhibited MRSA at a minimum concentration of 0.625 mg/mL and were bactericidal at a minimum concentration of 1.25 mg/mL. In MTT assays, ZnO-NPs showed no toxicity to HS-27 fibroblasts. The supernatant of Weissella confusa UPM22MT04 could be used to synthesize ZnO-NPs, which are an antibacterial agent, eco-friendly and nontoxic. University of Baghdad 2023 Article PeerReviewed Al-Tameemi, A. I. and Masarudin, M. J. and A. Rahim, R. and Timms, V. and Neilan, B. and Isa, N. M. (2023) Antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of Weissella confusa UPM22MT04. Iraqi Journal of Agricultural Sciences, 54 (5). 1209 - 1222. ISSN 0075-0530; ESSN: 2410-0862 https://jcoagri.uobaghdad.edu.iq/index.php/intro/article/view/1816 10.36103/ijas.v54i5.1816 |
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This study was aimed to produce zinc oxide nanoparticles (ZnO-NPs) using the supernatant of Weissella confusa UPM22MT04 and assess their effectiveness in inhibiting methicillin resistant Staphylococcus aureus (MRSA). An isolate of Weissella confusa UPM22MT04 was isolated from a wastewater treatment plant in Johor, Malaysia, and was utilized to synthesize ZnO-NPs. The synthesized ZnO-NPs were characterized through several techniques, including UV-visible spectroscopy, Fourier-transform infrared spectroscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, and dynamic light scattering. Monodisperse spherical ZnO-NPs of 1.7 - 7.9 nm were obtained with 0.1 M zinc nitrate at 80°C. The biosynthesized ZnO-NPs exhibited vigorous inhibitory activity against MRSA. Results found that ZnO-NPs inhibited MRSA at a minimum concentration of 0.625 mg/mL and were bactericidal at a minimum concentration of 1.25 mg/mL. In MTT assays, ZnO-NPs showed no toxicity to HS-27 fibroblasts. The supernatant of Weissella confusa UPM22MT04 could be used to synthesize ZnO-NPs, which are an antibacterial agent, eco-friendly and nontoxic. |
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Al-Tameemi, A. I. Masarudin, M. J. A. Rahim, R. Timms, V. Neilan, B. Isa, N. M. |
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Al-Tameemi, A. I. Masarudin, M. J. A. Rahim, R. Timms, V. Neilan, B. Isa, N. M. Antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of Weissella confusa UPM22MT04 |
author_facet |
Al-Tameemi, A. I. Masarudin, M. J. A. Rahim, R. Timms, V. Neilan, B. Isa, N. M. |
author_sort |
Al-Tameemi, A. I. |
title |
Antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of Weissella confusa UPM22MT04 |
title_short |
Antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of Weissella confusa UPM22MT04 |
title_full |
Antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of Weissella confusa UPM22MT04 |
title_fullStr |
Antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of Weissella confusa UPM22MT04 |
title_full_unstemmed |
Antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of Weissella confusa UPM22MT04 |
title_sort |
antibacterial properties of zinc oxide nanoparticles synthesized by the supernatant of weissella confusa upm22mt04 |
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University of Baghdad |
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2023 |
url |
http://psasir.upm.edu.my/id/eprint/106607/ https://jcoagri.uobaghdad.edu.iq/index.php/intro/article/view/1816 |
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