Cover Image

A pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study

Objective: Dialysate in peritoneal cavity is expected to affect multifrequency bioimpedance analysis measurement in peritoneal dialysis patients. Nevertheless, the extent of dialysate influence on multifrequency bioimpedance analysis measurement appears to be varied with the weight used in the calcu...

Full description

Saved in:
Bibliographic Details
Main Authors: Wah Lee, Shi, Mat Daud, Zulfitri Azuan, Lim, Jun-Hao, Lim, Cordelia-Kheng-May, Ibrahim, Imliya, Chan, Yoke-Mun, Zakaria, Nor Fadhlina
Format: Article
Published: Turkish Society of Nephrology 2024
Online Access:http://psasir.upm.edu.my/id/eprint/106290/
https://turkjnephrol.org/en/a-pragmatic-approach-to-derogate-dialysate-induced-body-composition-bias-in-peritoneal-dialysis-patients-insight-from-a-single-center-study-137166
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.106290
record_format eprints
spelling my.upm.eprints.1062902024-05-14T13:09:31Z http://psasir.upm.edu.my/id/eprint/106290/ A pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study Wah Lee, Shi Mat Daud, Zulfitri Azuan Lim, Jun-Hao Lim, Cordelia-Kheng-May Ibrahim, Imliya Chan, Yoke-Mun Zakaria, Nor Fadhlina Objective: Dialysate in peritoneal cavity is expected to affect multifrequency bioimpedance analysis measurement in peritoneal dialysis patients. Nevertheless, the extent of dialysate influence on multifrequency bioimpedance analysis measurement appears to be varied with the weight used in the calculation. Thus, this study aimed to evaluate the impact of dialysate on body composition when different weights were used in the multifrequency bioimpedance analysis measurement. Methods: This single-center study was conducted among 30 peritoneal dialysis patients in a tertiary referral hospital. Multifrequency bioimpedance analysis parameters were evaluated under 3 different conditions: (i) actual body weight without dialysate instilled (reference method); (ii) dialysate-included body weight with dialysate instilled (DIBW), and (iii) actual body weight with dialysate instilled (ABW). Differences, reproducibility, and agreements between the reference method with dialysate-included body weight and actual body weight methods were examined using repeated measure analysis of variance, intraclass correlation coefficients, and Bland–Altman analysis, respectively. Results: Pairwise comparisons showed significant differences (P <.05) between reference and DIBW in most multifrequency bioimpedance analysis parameters (10/14) except on intracellular water (P = .286), skeletal muscle mass (P = .518), skeletal muscle index (P = .079), and body cell mass (P = .357). Meanwhile, only extracellular water (P <.001), extracellular/ total body water (P <.001), and bone mineral content (P <.001) were significantly different for ABW when compared to the reference. Compared to DIBW, ABW showed lesser measurement bias, narrower 95 limit of agreement, and better reproducibility in most of the multifrequency bioimpedance analysis parameters with reference method. Conclusion: We concluded that dialysate-induced multifrequency bioimpedance analysis bias can be reasonably corrected using patient’s actual body weight upon body composition assessment. Turkish Society of Nephrology 2024-01 Article PeerReviewed Wah Lee, Shi and Mat Daud, Zulfitri Azuan and Lim, Jun-Hao and Lim, Cordelia-Kheng-May and Ibrahim, Imliya and Chan, Yoke-Mun and Zakaria, Nor Fadhlina (2024) A pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study. Turkish Journal of Nephrology, 33 (1). pp. 68-75. ISSN 2667-4440 https://turkjnephrol.org/en/a-pragmatic-approach-to-derogate-dialysate-induced-body-composition-bias-in-peritoneal-dialysis-patients-insight-from-a-single-center-study-137166 10.5152/turkjnephrol.2023.23543
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description Objective: Dialysate in peritoneal cavity is expected to affect multifrequency bioimpedance analysis measurement in peritoneal dialysis patients. Nevertheless, the extent of dialysate influence on multifrequency bioimpedance analysis measurement appears to be varied with the weight used in the calculation. Thus, this study aimed to evaluate the impact of dialysate on body composition when different weights were used in the multifrequency bioimpedance analysis measurement. Methods: This single-center study was conducted among 30 peritoneal dialysis patients in a tertiary referral hospital. Multifrequency bioimpedance analysis parameters were evaluated under 3 different conditions: (i) actual body weight without dialysate instilled (reference method); (ii) dialysate-included body weight with dialysate instilled (DIBW), and (iii) actual body weight with dialysate instilled (ABW). Differences, reproducibility, and agreements between the reference method with dialysate-included body weight and actual body weight methods were examined using repeated measure analysis of variance, intraclass correlation coefficients, and Bland–Altman analysis, respectively. Results: Pairwise comparisons showed significant differences (P <.05) between reference and DIBW in most multifrequency bioimpedance analysis parameters (10/14) except on intracellular water (P = .286), skeletal muscle mass (P = .518), skeletal muscle index (P = .079), and body cell mass (P = .357). Meanwhile, only extracellular water (P <.001), extracellular/ total body water (P <.001), and bone mineral content (P <.001) were significantly different for ABW when compared to the reference. Compared to DIBW, ABW showed lesser measurement bias, narrower 95 limit of agreement, and better reproducibility in most of the multifrequency bioimpedance analysis parameters with reference method. Conclusion: We concluded that dialysate-induced multifrequency bioimpedance analysis bias can be reasonably corrected using patient’s actual body weight upon body composition assessment.
format Article
author Wah Lee, Shi
Mat Daud, Zulfitri Azuan
Lim, Jun-Hao
Lim, Cordelia-Kheng-May
Ibrahim, Imliya
Chan, Yoke-Mun
Zakaria, Nor Fadhlina
spellingShingle Wah Lee, Shi
Mat Daud, Zulfitri Azuan
Lim, Jun-Hao
Lim, Cordelia-Kheng-May
Ibrahim, Imliya
Chan, Yoke-Mun
Zakaria, Nor Fadhlina
A pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study
author_facet Wah Lee, Shi
Mat Daud, Zulfitri Azuan
Lim, Jun-Hao
Lim, Cordelia-Kheng-May
Ibrahim, Imliya
Chan, Yoke-Mun
Zakaria, Nor Fadhlina
author_sort Wah Lee, Shi
title A pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study
title_short A pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study
title_full A pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study
title_fullStr A pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study
title_full_unstemmed A pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study
title_sort pragmatic approach to derogate dialysate-induced body composition bias in peritoneal dialysis patients: insight from a single-center study
publisher Turkish Society of Nephrology
publishDate 2024
url http://psasir.upm.edu.my/id/eprint/106290/
https://turkjnephrol.org/en/a-pragmatic-approach-to-derogate-dialysate-induced-body-composition-bias-in-peritoneal-dialysis-patients-insight-from-a-single-center-study-137166
_version_ 1800093812095188992
score 13.211869

Similar Items