Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2
Loss of function of the neurofibromatosis type 2 (NF2) tumor suppressor gene leads to the formation of schwannomas, meningiomas, and ependymomas, comprising ∼50% of all sporadic cases of primary nervous system tumors. NF2 syndrome is an autosomal dominant condition, with bi-allelic inactivation of g...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Published: |
Cell Press
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/101608/ https://www.sciencedirect.com/science/article/pii/S2329050122000912?via%3Dihub |
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