Cover Image

Challenges and complications of poly (lactic-co-glycolic acid)-based long-acting drug product development

Poly(lactic-co-glycolic acid) (PLGA) is one of the preferred polymeric inactive ingredients for long-acting parenteral drug products that are constituted of complex formulations. Despite over 30 years of use, there are still many challenges faced by researchers in formulation-related aspects pertain...

Full description

Saved in:

Bibliographic Details
Main Authors:	Lim, Yi Wen, Tan, Wen Siang, Ho, Kok Lian, Mariatulqabtiah, Abdul Razak, Abu Kasim, Noor Hayaty, Abd. Rahman, Noorsaadah, Wong, Tin Wui, Chee, Chin Fei Chee
Format:	Article
Published:	MDPI 2022
Online Access:	http://psasir.upm.edu.my/id/eprint/100651/ https://www.mdpi.com/1999-4923/14/3/614
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Preparation and characterization of Poly(Lactic Acid)/Poly (Ethylene Glycol)-Poly(Propyl Glycol)-Poly(Ethylene Glycol) blended nanofiber membranes for fog collection
by: Aijaz, Muhammad Omer, et al.
Published: (2023)

Characterization and melt spinning of poly (lactic acid)/poly (ethylene glycol) blends
by: Mohd Akhir, Nur atiqah, et al.
Published: (2021)

Characterization and melt spinning of poly (lactic acid)/poly (ethylene glycol) blends
by: Akhir, Nur Atiqah Mohd, et al.
Published: (2021)

Poly(lactic acid)/poly(ethylene glycol) polymer nanocomposites: effects of graphene nanoplatelets
by: Chieng, Buong Woei, et al.
Published: (2014)

Stealth coating of nanoparticles in drug-delivery systems
by: Fam, See Yee, et al.
Published: (2020)

Stealth coating of nanoparticles in drug delivery system
by: Fam, See Yee, et al.
Published: (2020)

Centrifugation facilitates incorporation of fibrin in poly(lactic-co-glycolic acid) scaffold
by: Mohamad, Mohd Yusof, et al.
Published: (2014)

Biodegradable poly(D,L-lactic-co-glycolic acid)-based micro/nanoparticles for sustained release of protein drugs - a review
by: Ansary , Rezaul H., et al.
Published: (2014)

Characterization of poly (lactic acid) _ poly (ethylene) glycol blends prepared for melt drawn spinning process
by: Mohd Akhir, Nur Atiqah, et al.
Published: (2019)

Drug-eluting coating of ginsenoside Rg1 and Re incorporated poly(lactic-co-glycolic acid) on stainless steel 316L: physicochemical and drug release analyses
by: Miswan, Z., et al.
Published: (2016)

Modeling of Hyaluronic Acid Containing Anti-Cancer Drugs-Loaded Poly lactic-co-Glycolic Acid Bioconjugates for Targeted Delivery to Cancer Cells
Published: (2012)

Plasticized poly(lactic acid) with low molecular weight poly(ethylene glycol) : mechanical, thermal, and morphology properties
by: Chieng, Buong Woei, et al.
Published: (2013)

Treatment of palm oil mill effluent by poly(L-lactic acid)-poly(ethylene glycol)/silica membrane
by: Fatimah Zahrah Mohd Kamil,, et al.
Published: (2020)

Characterisation and production of Poly (Lactic/Acid)/poly (Ethylene Glycol) microfiber via melt drawn spinning process
by: Othman, Maizatulnisa, et al.
Published: (2021)

Preparation of Poly (LACTIC ACID) (PLA) Microspheres for Drug Delivery System
by: Tham Cho Yin, Cho Yin
Published: (2015)

Preparation Of Poly(Lactic Acid) (Pla) Microspheres For Drug Delivery System
by: Tham , Cho Yin
Published: (2015)

The use of poly(lactic-co-glycolic acid) and fibrin scaffolds for articular cartilage tissue engineering
by: Abdul Rahman, Rozlin, et al.
Published: (2014)

Synthesization and characterization of chlorhexidine/calcium phosphate/poly(lactic-co-glycolic acid) bone cement
by: Daud, N. M., et al.
Published: (2019)

Characterization of poly (lactic-co-glycolic acid) / atelocollagen hybrid scaffold for intervertebral disc regeneration
by: Mohamad, Mohd Yusof, et al.
Published: (2016)

Preparation, characterization, and bioactivity evaluation of curcumin-loaded poly (lactic-co-glycolic acid) nanoparticles
by: Ezani, Muhammad Haziq, et al.
Published: (2024)

The effect of molecular weight on the surface and permeation of poly(L-lactic acid)-poly(ethylene glycol) membrane with activated carbon filler
by: Afifah Muhamad Sidik,, et al.
Published: (2018)

Mechanical, thermal, and morphology properties of poly(lactic acid) plasticized with poly(ethylene glycol) and epoxidized palm oil hybrid plasticizer
by: Chieng, Buong Woei, et al.
Published: (2016)

Cartilaginous properties of nucleus pulposus cells seeded on poly(lactic-co-glycolic acid)-based scaffolds
by: Md Nazir, Noorhidayah, et al.
Published: (2014)

Influence of poly lactic-co-glycolic acid scaffold with concentrated growth factor on human osteoblast cells
by: Mohd Noh, Nur Zety, et al.
Published: (2021)

Conjugation Of Bioactive Groups To Poly(Lactic Acid) Microspheres For Drug Delivery Systems
by: Sabee, Mohd Meer Saddiq Mohd
Published: (2020)

Ginseng encapsulated Poly(Lactic-co-Glycolic Acid)/ Polyaniline microcapsules coated on stainless steel 316L using electrodeposition technique for drug-eluting stent application
by: Lukman, Siti Khadijah
Published: (2021)

Biodegradable poly (lactic acid)/poly (ethylene glycol) reinforced multi-walled carbon nanotube nanocomposite fabrication, characterization, properties, and applications
by: Ahmad, Ahmad Fahad, et al.
Published: (2020)

Biodegradable Poly (lactic acid)/Poly (ethylene glycol) reinforced multi-walled Carbon Nanotube Nanocomposite fabrication, characterization, properties, and applications
by: Ahmad, Ahmad Fahad, et al.
Published: (2020)

Shielding of hepatitis B virus-like nanoparticle with poly(2-ethyl-2-oxazoline)
by: Fam, See Yee, et al.
Published: (2019)

Fabrication and evaluation of mechanical strength of poly(lactic-co-glycolic acid) scaffold incorporated with atelocollagen type II
by: Mohamad, Mohd Yusof, et al.
Published: (2016)

Structural and functional properties of neocartilage construct engineered in poly (Lactic-co-Glycolic Acid) (PLGA) based scaffolds
by: Md Ali @ Tahir, Aisyah Hanani, et al.
Published: (2019)

In vitro evaluation of poly (lactic acid-co-glycolic acid)/ atelocollagen/fibrin bioscaffold for annulus fibrosus regeneration
by: Mohamad, Mohd Yusof, et al.
Published: (2020)

An overview on the use of concentrated growth factor (CGF) and Poly Lactic-co-Glycolic Acid (PLGA) in periodontal regeneration
by: Mohd Noh, Nur Zety, et al.
Published: (2019)

In Vitro Anticancer Properties of Linamarin Controlled Release From Biodegradable Poly-Lactic Co-Glycolic Acid Nanoparticle
by: Alfourjani, Wedad Ashour
Published: (2005)

Everolimus immobilisation using polydopamine intermediate layer on poly(l-lactic acid)/poly(d-lactic acid) scaffold for sustainable anti-proliferative drug release
by: Jumat, Mohamad Amin, et al.
Published: (2022)

Chemically reduced graphene oxide-reinforced poly(lactic acid)/poly(ethylene glycol) nanocomposites: preparation, characterization, and applications in electromagnetic interference shielding
by: Ahmad, Ahmad Fahad, et al.
Published: (2019)

Strontium-hydroxyapatite incorporated Poly(Hydroxybutyrate-CO-Hydroxyvalerate)/ Poly(Lactic-CO-Glycolic Acid) electrospun nanofibers for bone tissue engineering scaffold
by: Hassan, Mohd. Izzat
Published: (2020)

Fibrin and poly(lactic-co-glycolic acid) hybrid scaffold promotes early chondrogenesis of articular chondrocytes: an in vitro study
by: Sha'ban, Munirah, et al.
Published: (2008)

The use of fibrin and poly(lactic-co-glycolic acid) hybrid scaffold for articular cartilage tissue engineering: an in vivo analysis
by: Sha'ban, Munirah, et al.
Published: (2008)

Antibacterial and cytocompatibility analyses on triple layered poly(lactic-co-glycolic acid)/nanoapatite/lauric acid composite membrane
by: Saarani, Nur Najiha
Published: (2016)