Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies

Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a r...

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Main Authors: Molujin, Arnold Marshall, Abbasiliasi, Sahar, Nurdin, Armania, Lee, Ping-Chin, Gansau, Jualang Azlan, Jawan, Roslina
Format: Article
Published: MDPI 2022
Online Access:http://psasir.upm.edu.my/id/eprint/100506/
https://www.mdpi.com/2072-6694/14/19/4758
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spelling my.upm.eprints.1005062023-11-29T06:41:34Z http://psasir.upm.edu.my/id/eprint/100506/ Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies Molujin, Arnold Marshall Abbasiliasi, Sahar Nurdin, Armania Lee, Ping-Chin Gansau, Jualang Azlan Jawan, Roslina Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a result, this prompts a search for an alternative treatment without exhibiting any additional side effects. One of the promising novel therapeutic candidates against cancer is an antimicrobial peptide produced by bacteria called bacteriocin. It is a non-toxic peptide that is reported to exhibit potency against cancer cell lines. Experimental studies have outlined the therapeutic potential of bacteriocin against various cancer cell lines. In this review article, the paper focuses on the various bacteriocins and their cytotoxic effects, mode of action and efficacies as therapeutic agents against various cancer cell lines. MDPI 2022-09-29 Article PeerReviewed Molujin, Arnold Marshall and Abbasiliasi, Sahar and Nurdin, Armania and Lee, Ping-Chin and Gansau, Jualang Azlan and Jawan, Roslina (2022) Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies. Cancers, 14 (19). art. no. 4758. pp. 1-14. ISSN 2072-6694 https://www.mdpi.com/2072-6694/14/19/4758 10.3390/cancers14194758
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a result, this prompts a search for an alternative treatment without exhibiting any additional side effects. One of the promising novel therapeutic candidates against cancer is an antimicrobial peptide produced by bacteria called bacteriocin. It is a non-toxic peptide that is reported to exhibit potency against cancer cell lines. Experimental studies have outlined the therapeutic potential of bacteriocin against various cancer cell lines. In this review article, the paper focuses on the various bacteriocins and their cytotoxic effects, mode of action and efficacies as therapeutic agents against various cancer cell lines.
format Article
author Molujin, Arnold Marshall
Abbasiliasi, Sahar
Nurdin, Armania
Lee, Ping-Chin
Gansau, Jualang Azlan
Jawan, Roslina
spellingShingle Molujin, Arnold Marshall
Abbasiliasi, Sahar
Nurdin, Armania
Lee, Ping-Chin
Gansau, Jualang Azlan
Jawan, Roslina
Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies
author_facet Molujin, Arnold Marshall
Abbasiliasi, Sahar
Nurdin, Armania
Lee, Ping-Chin
Gansau, Jualang Azlan
Jawan, Roslina
author_sort Molujin, Arnold Marshall
title Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies
title_short Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies
title_full Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies
title_fullStr Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies
title_full_unstemmed Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies
title_sort bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies
publisher MDPI
publishDate 2022
url http://psasir.upm.edu.my/id/eprint/100506/
https://www.mdpi.com/2072-6694/14/19/4758
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