A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)

A Colorectal neuroendocrine carcinoma (CRNEC) is a rare malignancy of the colon. It is a tumour with a heterogeneous presentation, further complicated by its disunified nomenclature, which imposed a challenge in detection and management. We present a rare case of hepatic flexure neuroendocrine carci...

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Main Authors: Jasmani, Asraf Haslam, Khazalle, Muhammad Haekal, Oaris, Iqtidaar, Mohamad, Ikhwan Sani
Format: Article
Language:English
Published: UPM Press 2022
Online Access:http://psasir.upm.edu.my/id/eprint/100345/1/A%20rare%20case%20of%20hepatic%20flexure%20Gastroenteropancreatic%20neuroendocrine%20carcinoma%20%28GEP-NEC%29.pdf
http://psasir.upm.edu.my/id/eprint/100345/
https://medic.upm.edu.my/our_journal/volume_18_2022/mjmhs_vol18_supp_13_oktober_2022-69861
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spelling my.upm.eprints.1003452023-12-26T07:33:14Z http://psasir.upm.edu.my/id/eprint/100345/ A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) Jasmani, Asraf Haslam Khazalle, Muhammad Haekal Oaris, Iqtidaar Mohamad, Ikhwan Sani A Colorectal neuroendocrine carcinoma (CRNEC) is a rare malignancy of the colon. It is a tumour with a heterogeneous presentation, further complicated by its disunified nomenclature, which imposed a challenge in detection and management. We present a rare case of hepatic flexure neuroendocrine carcinoma in a 47-year-old lady who complained of 5 months history of progressively worsening, intermittent colicky central abdominal pain, altered bowel habit, vomiting, and significant weight loss. She presented with lethargy, distended abdomen and fullness at its centre. The abdominal x-ray showed generalised bowel dilatation, with the subsequent CT scan abdomen showing obstructed hepatic flexure tumour. She underwent emergency exploratory laparotomy and right hemicolectomy with a double-barrel stoma. Intraoperatively, a hepatic flexure tumour, an engorged and nodular appendix with multiple mesenteric lymph nodes. Her recovery was unremarkable. Histopathology examination showed neuroendocrine tumour Grade 3 arising from hepatic flexure with no appendiceal involvement. UPM Press 2022-10 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/100345/1/A%20rare%20case%20of%20hepatic%20flexure%20Gastroenteropancreatic%20neuroendocrine%20carcinoma%20%28GEP-NEC%29.pdf Jasmani, Asraf Haslam and Khazalle, Muhammad Haekal and Oaris, Iqtidaar and Mohamad, Ikhwan Sani (2022) A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC). Malaysian Journal of Medicine and Health Sciences, 18 (suppl. 13). art. no. 6. 21 - 24. ISSN 2636-9346 https://medic.upm.edu.my/our_journal/volume_18_2022/mjmhs_vol18_supp_13_oktober_2022-69861 10.47836/mjmhs18.s13.7
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description A Colorectal neuroendocrine carcinoma (CRNEC) is a rare malignancy of the colon. It is a tumour with a heterogeneous presentation, further complicated by its disunified nomenclature, which imposed a challenge in detection and management. We present a rare case of hepatic flexure neuroendocrine carcinoma in a 47-year-old lady who complained of 5 months history of progressively worsening, intermittent colicky central abdominal pain, altered bowel habit, vomiting, and significant weight loss. She presented with lethargy, distended abdomen and fullness at its centre. The abdominal x-ray showed generalised bowel dilatation, with the subsequent CT scan abdomen showing obstructed hepatic flexure tumour. She underwent emergency exploratory laparotomy and right hemicolectomy with a double-barrel stoma. Intraoperatively, a hepatic flexure tumour, an engorged and nodular appendix with multiple mesenteric lymph nodes. Her recovery was unremarkable. Histopathology examination showed neuroendocrine tumour Grade 3 arising from hepatic flexure with no appendiceal involvement.
format Article
author Jasmani, Asraf Haslam
Khazalle, Muhammad Haekal
Oaris, Iqtidaar
Mohamad, Ikhwan Sani
spellingShingle Jasmani, Asraf Haslam
Khazalle, Muhammad Haekal
Oaris, Iqtidaar
Mohamad, Ikhwan Sani
A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)
author_facet Jasmani, Asraf Haslam
Khazalle, Muhammad Haekal
Oaris, Iqtidaar
Mohamad, Ikhwan Sani
author_sort Jasmani, Asraf Haslam
title A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)
title_short A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)
title_full A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)
title_fullStr A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)
title_full_unstemmed A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)
title_sort rare case of hepatic flexure gastroenteropancreatic neuroendocrine carcinoma (gep-nec)
publisher UPM Press
publishDate 2022
url http://psasir.upm.edu.my/id/eprint/100345/1/A%20rare%20case%20of%20hepatic%20flexure%20Gastroenteropancreatic%20neuroendocrine%20carcinoma%20%28GEP-NEC%29.pdf
http://psasir.upm.edu.my/id/eprint/100345/
https://medic.upm.edu.my/our_journal/volume_18_2022/mjmhs_vol18_supp_13_oktober_2022-69861
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