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Calcium phosphate /poly (Ethylene glycol) bone cement: Cell culture performance

Calcium phosphate cement (CPC) for injectable bone cement application has been developed in this study. The CPC was produced using a novel wet chemical precipitation method derived hydroxyapatite (HA) powder. The calcium and phosphorus precursors used to synthesize HA powder were calcium hydroxide,...

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Main Authors: Hablee S., Samsudin N., Sopyan I., Mel M., Salleh H.M., Rahman M.M., Hashim Y.Z.H.-Y., Raus R.A.
Other Authors: 57193084272
Format: Article
Published: Blue Eyes Intelligence Engineering and Sciences Publication 2023
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spelling my.uniten.dspace-247552023-05-29T15:26:43Z Calcium phosphate /poly (Ethylene glycol) bone cement: Cell culture performance Hablee S. Samsudin N. Sopyan I. Mel M. Salleh H.M. Rahman M.M. Hashim Y.Z.H.-Y. Raus R.A. 57193084272 34771895600 23482484000 23668032700 6602485216 55328831100 9435676000 54893399600 Calcium phosphate cement (CPC) for injectable bone cement application has been developed in this study. The CPC was produced using a novel wet chemical precipitation method derived hydroxyapatite (HA) powder. The calcium and phosphorus precursors used to synthesize HA powder were calcium hydroxide, Ca(OH) 2 , and di-ammonium hydrogen phosphate, (NH 4 ) 2 HPO 4 . The HA powder was mixed with distilled water at certain powder-to-liquid (P/L) ratios. In this study, the P/L ratios were varied at 1.3 and 1.7. PEG was added into CPC with the P/L ratio of 1.3, and it was adjusted at 1 and 5 wt%. The results of this study revealed that higher P/L ratio contributed to the decreased in porosity of CPC. Meanwhile, the addition of PEG increased the porosity of CPC. This is significant for cells adhesion and proliferation, such that cell proliferate faster and better adhesion with the incorporation of PEG into CPC. The cell culture on CPC has proven that the fabricated CPC shows no toxic reaction and cells grow well. � BEIESP. Final 2023-05-29T07:26:42Z 2023-05-29T07:26:42Z 2019 Article 2-s2.0-85065214805 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065214805&partnerID=40&md5=ff6efe8cb34760110e37b7621acf5177 https://irepository.uniten.edu.my/handle/123456789/24755 7 6 82 86 Blue Eyes Intelligence Engineering and Sciences Publication Scopus
institution Universiti Tenaga Nasional
building UNITEN Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Tenaga Nasional
content_source UNITEN Institutional Repository
url_provider http://dspace.uniten.edu.my/
description Calcium phosphate cement (CPC) for injectable bone cement application has been developed in this study. The CPC was produced using a novel wet chemical precipitation method derived hydroxyapatite (HA) powder. The calcium and phosphorus precursors used to synthesize HA powder were calcium hydroxide, Ca(OH) 2 , and di-ammonium hydrogen phosphate, (NH 4 ) 2 HPO 4 . The HA powder was mixed with distilled water at certain powder-to-liquid (P/L) ratios. In this study, the P/L ratios were varied at 1.3 and 1.7. PEG was added into CPC with the P/L ratio of 1.3, and it was adjusted at 1 and 5 wt%. The results of this study revealed that higher P/L ratio contributed to the decreased in porosity of CPC. Meanwhile, the addition of PEG increased the porosity of CPC. This is significant for cells adhesion and proliferation, such that cell proliferate faster and better adhesion with the incorporation of PEG into CPC. The cell culture on CPC has proven that the fabricated CPC shows no toxic reaction and cells grow well. � BEIESP.
author2 57193084272
author_facet 57193084272
Hablee S.
Samsudin N.
Sopyan I.
Mel M.
Salleh H.M.
Rahman M.M.
Hashim Y.Z.H.-Y.
Raus R.A.
format Article
author Hablee S.
Samsudin N.
Sopyan I.
Mel M.
Salleh H.M.
Rahman M.M.
Hashim Y.Z.H.-Y.
Raus R.A.
spellingShingle Hablee S.
Samsudin N.
Sopyan I.
Mel M.
Salleh H.M.
Rahman M.M.
Hashim Y.Z.H.-Y.
Raus R.A.
Calcium phosphate /poly (Ethylene glycol) bone cement: Cell culture performance
author_sort Hablee S.
title Calcium phosphate /poly (Ethylene glycol) bone cement: Cell culture performance
title_short Calcium phosphate /poly (Ethylene glycol) bone cement: Cell culture performance
title_full Calcium phosphate /poly (Ethylene glycol) bone cement: Cell culture performance
title_fullStr Calcium phosphate /poly (Ethylene glycol) bone cement: Cell culture performance
title_full_unstemmed Calcium phosphate /poly (Ethylene glycol) bone cement: Cell culture performance
title_sort calcium phosphate /poly (ethylene glycol) bone cement: cell culture performance
publisher Blue Eyes Intelligence Engineering and Sciences Publication
publishDate 2023
_version_ 1806425895664091136
score 13.211869

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