Design and fabrication of polydimethylsiloxane based low cost microfluidic for ultra-fast diagnostic applications

Diagnostic tools such as Point-of-Care (POC) analysis usually requires an on-site testing and measurements. Hence, to ease the fluid sample handling, microfluidics technology has been opted frequently to be incorporated with lab-on-chip (LOC). Therefore, an easy and conventional method of design and...

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Main Authors: Balakrishnan S.R., Hashim U., Sahrim M., Ismail I., Jamaludin J., Ismail W.Z.W., Perumal V., Haarindraprasad R., Mahalingam S.
Other Authors: 57216524505
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Published: Penerbit UTHM 2023
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spelling my.uniten.dspace-241462023-05-29T14:56:02Z Design and fabrication of polydimethylsiloxane based low cost microfluidic for ultra-fast diagnostic applications Balakrishnan S.R. Hashim U. Sahrim M. Ismail I. Jamaludin J. Ismail W.Z.W. Perumal V. Haarindraprasad R. Mahalingam S. 57216524505 22633937800 57200505665 57202916113 54787892800 57210463026 56966716600 56725750500 55434075500 Diagnostic tools such as Point-of-Care (POC) analysis usually requires an on-site testing and measurements. Hence, to ease the fluid sample handling, microfluidics technology has been opted frequently to be incorporated with lab-on-chip (LOC). Therefore, an easy and conventional method of design and fabrication of the microfluidic device implemented. In this study, the device is fabricated with Polydimethylsiloxane (PDMS) and SU-8 using soft lithography technique. Herein, we focus on fluid transportation which is applied in clinical diagnostics and the transfer rate to the desired position as well as the fluid leakage during the transportation. Hence, the microfluidic sample transport channeling provides a practical solution for POC technological advances to study the biological systems that yield a better result in quantitative measurements and providing researchers new tools for life science research. � Penerbit UTHM. Final 2023-05-29T06:56:02Z 2023-05-29T06:56:02Z 2018 Article 10.30880/ijie.2018.10.04.018 2-s2.0-85057149030 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057149030&doi=10.30880%2fijie.2018.10.04.018&partnerID=40&md5=c9d231eac2915ae65122af4a691b4ccd https://irepository.uniten.edu.my/handle/123456789/24146 10 4 109 113 All Open Access, Bronze, Green Penerbit UTHM Scopus
institution Universiti Tenaga Nasional
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description Diagnostic tools such as Point-of-Care (POC) analysis usually requires an on-site testing and measurements. Hence, to ease the fluid sample handling, microfluidics technology has been opted frequently to be incorporated with lab-on-chip (LOC). Therefore, an easy and conventional method of design and fabrication of the microfluidic device implemented. In this study, the device is fabricated with Polydimethylsiloxane (PDMS) and SU-8 using soft lithography technique. Herein, we focus on fluid transportation which is applied in clinical diagnostics and the transfer rate to the desired position as well as the fluid leakage during the transportation. Hence, the microfluidic sample transport channeling provides a practical solution for POC technological advances to study the biological systems that yield a better result in quantitative measurements and providing researchers new tools for life science research. � Penerbit UTHM.
author2 57216524505
author_facet 57216524505
Balakrishnan S.R.
Hashim U.
Sahrim M.
Ismail I.
Jamaludin J.
Ismail W.Z.W.
Perumal V.
Haarindraprasad R.
Mahalingam S.
format Article
author Balakrishnan S.R.
Hashim U.
Sahrim M.
Ismail I.
Jamaludin J.
Ismail W.Z.W.
Perumal V.
Haarindraprasad R.
Mahalingam S.
spellingShingle Balakrishnan S.R.
Hashim U.
Sahrim M.
Ismail I.
Jamaludin J.
Ismail W.Z.W.
Perumal V.
Haarindraprasad R.
Mahalingam S.
Design and fabrication of polydimethylsiloxane based low cost microfluidic for ultra-fast diagnostic applications
author_sort Balakrishnan S.R.
title Design and fabrication of polydimethylsiloxane based low cost microfluidic for ultra-fast diagnostic applications
title_short Design and fabrication of polydimethylsiloxane based low cost microfluidic for ultra-fast diagnostic applications
title_full Design and fabrication of polydimethylsiloxane based low cost microfluidic for ultra-fast diagnostic applications
title_fullStr Design and fabrication of polydimethylsiloxane based low cost microfluidic for ultra-fast diagnostic applications
title_full_unstemmed Design and fabrication of polydimethylsiloxane based low cost microfluidic for ultra-fast diagnostic applications
title_sort design and fabrication of polydimethylsiloxane based low cost microfluidic for ultra-fast diagnostic applications
publisher Penerbit UTHM
publishDate 2023
_version_ 1806426174530781184
score 13.211869