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Genealogical study using mitochondrial DNA

This study examines the inheritance of maternal mitochondria DNA of a selected family. The sequence analysis was done by analyzing the mitochondrial D-loop region which are the hypervariable region I (HVR I), hypervariable region II (HVR II) and hypervariable region III (HVRIII). A total of 54 bucc...

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Bibliographic Details
Main Author: Lora, Anak Johi
Format: Final Year Project Report
Language:English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2011
Subjects:
Q Science (General)
Online Access:http://ir.unimas.my/id/eprint/5310/8/Lora.pdf
http://ir.unimas.my/id/eprint/5310/
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spelling my.unimas.ir.53102023-12-11T07:59:08Z http://ir.unimas.my/id/eprint/5310/ Genealogical study using mitochondrial DNA Lora, Anak Johi Q Science (General) This study examines the inheritance of maternal mitochondria DNA of a selected family. The sequence analysis was done by analyzing the mitochondrial D-loop region which are the hypervariable region I (HVR I), hypervariable region II (HVR II) and hypervariable region III (HVRIII). A total of 54 buccal cell samples collected from 54 individuals of the selected family. Phylogenetic analysis was done using bootstrap test of Neighbor- Joining (NJ) and pairwise distance was to determine the genetic distance among the family members. The result of the phylogenetic analysis indicated that HVR I was the most hypervariable region compared to HVR II and HVR III. However, the combinations of the entire three HVR regions produce the best results regarding the genealogical relationship among individual members of the family Universiti Malaysia Sarawak, (UNIMAS) 2011 Final Year Project Report NonPeerReviewed text en http://ir.unimas.my/id/eprint/5310/8/Lora.pdf Lora, Anak Johi (2011) Genealogical study using mitochondrial DNA. [Final Year Project Report] (Unpublished)
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic Q Science (General)
spellingShingle Q Science (General)
Lora, Anak Johi
Genealogical study using mitochondrial DNA
description This study examines the inheritance of maternal mitochondria DNA of a selected family. The sequence analysis was done by analyzing the mitochondrial D-loop region which are the hypervariable region I (HVR I), hypervariable region II (HVR II) and hypervariable region III (HVRIII). A total of 54 buccal cell samples collected from 54 individuals of the selected family. Phylogenetic analysis was done using bootstrap test of Neighbor- Joining (NJ) and pairwise distance was to determine the genetic distance among the family members. The result of the phylogenetic analysis indicated that HVR I was the most hypervariable region compared to HVR II and HVR III. However, the combinations of the entire three HVR regions produce the best results regarding the genealogical relationship among individual members of the family
format Final Year Project Report
author Lora, Anak Johi
author_facet Lora, Anak Johi
author_sort Lora, Anak Johi
title Genealogical study using mitochondrial DNA
title_short Genealogical study using mitochondrial DNA
title_full Genealogical study using mitochondrial DNA
title_fullStr Genealogical study using mitochondrial DNA
title_full_unstemmed Genealogical study using mitochondrial DNA
title_sort genealogical study using mitochondrial dna
publisher Universiti Malaysia Sarawak, (UNIMAS)
publishDate 2011
url http://ir.unimas.my/id/eprint/5310/8/Lora.pdf
http://ir.unimas.my/id/eprint/5310/
_version_ 1787140461462290432
score 13.211869

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