Dynamics of CD4-1+ and CD4-2+ lymphocytes in vaccinated ginbuna crucian carp Carassius auratus langsdorfii followed by cyprinid herpesvirus-2 (CyHV-2) challenge

Fish have two distinct CD4s: CD4-1 resembles the mammalian CD4 whereas CD4-2 is a second CD4 homolog. However, their roles in fish remain unclear. Ginbuna is susceptible to CyHV-2, whereas this infection can be prevented by a live-attenuated vaccine (P7-P8 strain). In this study, we investigated the...

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Bibliographic Details
Main Authors: Lik Ming, Lau, Hiroaki, Saito, Motohiko, Sano, Goshi, Kato
Format: Article
Language:English
Published: Elsevier Ltd. 2023
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Online Access:http://ir.unimas.my/id/eprint/45201/1/Dynamics.pdf
http://ir.unimas.my/id/eprint/45201/
https://www.sciencedirect.com/science/article/abs/pii/S0145305X23011205
https://doi.org/10.1016/j.dci.2023.104967
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