Environmental impacts, exposure pathways, and health effects of PFOA and PFOS

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals that have been widely utilized in various industries since the 1940s, and have now emerged as environmental contaminants. In recent years, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) have been restricted and r...

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Main Authors: Wee, Sze Yee, Ahmad Zaharin, Aris
Format: Article
Language:English
Published: Elsevier B.V. 2023
Subjects:
Online Access:http://ir.unimas.my/id/eprint/43394/3/Environment.pdf
http://ir.unimas.my/id/eprint/43394/
https://www.sciencedirect.com/science/article/pii/S0147651323011673
https://doi.org/10.1016/j.ecoenv.2023.115663
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spelling my.unimas.ir.433942023-11-16T01:56:52Z http://ir.unimas.my/id/eprint/43394/ Environmental impacts, exposure pathways, and health effects of PFOA and PFOS Wee, Sze Yee Ahmad Zaharin, Aris GE Environmental Sciences HD61 Risk Management QD Chemistry Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals that have been widely utilized in various industries since the 1940s, and have now emerged as environmental contaminants. In recent years, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) have been restricted and replaced with several alternatives. The high persistence, bioaccumulation, and toxicity of these substances have contributed to their emergence as environmental contaminants, and several aspects of their behavior remain largely unknown and require further investigation. The trace level of PFAS makes the development of a monitoring database challenging. Additionally, the potential health issues associated with PFAS are not yet fully understood due to ongoing research and inadequate evidence (experimental and epidemiological studies), especially with regard to the combined effects of exposure to PFAS mixtures and human health risks from drinking water consumption. This in-depth review offers unprecedented insights into the exposure pathways and toxicological impacts of PFAS, addressing critical knowledge gaps in their behaviors and health implications. It presents a comprehensive NABC—Needs, Approach, Benefits, and Challenges—analysis to guide future strategies for the sustainable monitoring and management of these pervasive environmental contaminants. Elsevier B.V. 2023-11-15 Article PeerReviewed text en http://ir.unimas.my/id/eprint/43394/3/Environment.pdf Wee, Sze Yee and Ahmad Zaharin, Aris (2023) Environmental impacts, exposure pathways, and health effects of PFOA and PFOS. Ecotoxicology and Environmental Safety, 267. pp. 1-15. ISSN 0147-6513 https://www.sciencedirect.com/science/article/pii/S0147651323011673 https://doi.org/10.1016/j.ecoenv.2023.115663
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic GE Environmental Sciences
HD61 Risk Management
QD Chemistry
spellingShingle GE Environmental Sciences
HD61 Risk Management
QD Chemistry
Wee, Sze Yee
Ahmad Zaharin, Aris
Environmental impacts, exposure pathways, and health effects of PFOA and PFOS
description Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals that have been widely utilized in various industries since the 1940s, and have now emerged as environmental contaminants. In recent years, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) have been restricted and replaced with several alternatives. The high persistence, bioaccumulation, and toxicity of these substances have contributed to their emergence as environmental contaminants, and several aspects of their behavior remain largely unknown and require further investigation. The trace level of PFAS makes the development of a monitoring database challenging. Additionally, the potential health issues associated with PFAS are not yet fully understood due to ongoing research and inadequate evidence (experimental and epidemiological studies), especially with regard to the combined effects of exposure to PFAS mixtures and human health risks from drinking water consumption. This in-depth review offers unprecedented insights into the exposure pathways and toxicological impacts of PFAS, addressing critical knowledge gaps in their behaviors and health implications. It presents a comprehensive NABC—Needs, Approach, Benefits, and Challenges—analysis to guide future strategies for the sustainable monitoring and management of these pervasive environmental contaminants.
format Article
author Wee, Sze Yee
Ahmad Zaharin, Aris
author_facet Wee, Sze Yee
Ahmad Zaharin, Aris
author_sort Wee, Sze Yee
title Environmental impacts, exposure pathways, and health effects of PFOA and PFOS
title_short Environmental impacts, exposure pathways, and health effects of PFOA and PFOS
title_full Environmental impacts, exposure pathways, and health effects of PFOA and PFOS
title_fullStr Environmental impacts, exposure pathways, and health effects of PFOA and PFOS
title_full_unstemmed Environmental impacts, exposure pathways, and health effects of PFOA and PFOS
title_sort environmental impacts, exposure pathways, and health effects of pfoa and pfos
publisher Elsevier B.V.
publishDate 2023
url http://ir.unimas.my/id/eprint/43394/3/Environment.pdf
http://ir.unimas.my/id/eprint/43394/
https://www.sciencedirect.com/science/article/pii/S0147651323011673
https://doi.org/10.1016/j.ecoenv.2023.115663
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score 13.211869