Staff View: Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves)

Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves)

Introduction: Piper betle Linn is one of the most commonly used compounding plants for ethno-medical purposes, with its extract generally used in modern products to enrich their functional efficacy. The extraction methods always lead to differences in the antimicrobial efficacy of methanol extracts...

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Main Authors:	Khin, Than Yee, Mohamad Iswandy, Ibrahim, Tin, Moe Nwe, Mya, Mya Thwin, Mar, Mar Lwin, Khin, Cho Aung, Ma, Saung Oo, Siti Zaleha, Raduan, Myat, San Yi
Format:	Article
Language:	English
Published:	RJPT 2023
Subjects:	S Agriculture (General)
Online Access:	http://ir.unimas.my/id/eprint/41824/2/Bio1.pdf http://ir.unimas.my/id/eprint/41824/ https://www.rjptonline.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20Pharmacy%20and%20Technology;PID=2023-16-3-75
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id	my.unimas.ir.41824
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spelling	my.unimas.ir.418242023-05-15T02:23:48Z http://ir.unimas.my/id/eprint/41824/ Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves) Khin, Than Yee Mohamad Iswandy, Ibrahim Tin, Moe Nwe Mya, Mya Thwin Mar, Mar Lwin Khin, Cho Aung Ma, Saung Oo Siti Zaleha, Raduan Myat, San Yi S Agriculture (General) Introduction: Piper betle Linn is one of the most commonly used compounding plants for ethno-medical purposes, with its extract generally used in modern products to enrich their functional efficacy. The extraction methods always lead to differences in the antimicrobial efficacy of methanol extracts of bioactive compounds. Purpose: The study was conducted to screen for bioactive compounds and determine their antimicrobial efficacy in a methanol extract of Piper betle and Murraya koenigi leaves from five different regions. Methodology: The phytochemical screening done according to the procedure that is implied in from Patil, et.al, with minor modifications by the researchers of the current study. Antimicrobial activity was determined; efficacy was measured by disc diffusion analysis. Results: Phytochemical screening revealed the presence of saponin, tannin, terpenoids, alkaloids and flavonoids in the extracts. The methanolic extract of betel leaves from all the selected regions except from Bau exhibited antimicrobial activities. Among them, extract from Kuching and Simunjan have no effect on E. coli. The methanolic extract of curry leaves from Kuching, Balai ringai and Bau have antimicrobial activities against Staph aureus and those from Balai ringai is also active against E.coli. Conclusion: Although there were previous reports of phytochemical screening and antimicrobial activities from the extract of these plants, there were still lack of research conducted on the specimens especially from our local community (Sarawak). The outcome of this study will help us to identify the bioactive compounds of the local samples and give us some pictures of their activities on how to ensure these plants can be brought forward based on the origin of the sample. RJPT 2023 Article PeerReviewed text en http://ir.unimas.my/id/eprint/41824/2/Bio1.pdf Khin, Than Yee and Mohamad Iswandy, Ibrahim and Tin, Moe Nwe and Mya, Mya Thwin and Mar, Mar Lwin and Khin, Cho Aung and Ma, Saung Oo and Siti Zaleha, Raduan and Myat, San Yi (2023) Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves). Research Journal of Pharmacy and Technology, 16 (3). pp. 1452-1458. ISSN 0974-360X https://www.rjptonline.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20Pharmacy%20and%20Technology;PID=2023-16-3-75 DOI: 10.52711/0974-360X.2023.00239
institution	Universiti Malaysia Sarawak
building	Centre for Academic Information Services (CAIS)
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Sarawak
content_source	UNIMAS Institutional Repository
url_provider	http://ir.unimas.my/
language	English
topic	S Agriculture (General)
spellingShingle	S Agriculture (General) Khin, Than Yee Mohamad Iswandy, Ibrahim Tin, Moe Nwe Mya, Mya Thwin Mar, Mar Lwin Khin, Cho Aung Ma, Saung Oo Siti Zaleha, Raduan Myat, San Yi Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves)
description	Introduction: Piper betle Linn is one of the most commonly used compounding plants for ethno-medical purposes, with its extract generally used in modern products to enrich their functional efficacy. The extraction methods always lead to differences in the antimicrobial efficacy of methanol extracts of bioactive compounds. Purpose: The study was conducted to screen for bioactive compounds and determine their antimicrobial efficacy in a methanol extract of Piper betle and Murraya koenigi leaves from five different regions. Methodology: The phytochemical screening done according to the procedure that is implied in from Patil, et.al, with minor modifications by the researchers of the current study. Antimicrobial activity was determined; efficacy was measured by disc diffusion analysis. Results: Phytochemical screening revealed the presence of saponin, tannin, terpenoids, alkaloids and flavonoids in the extracts. The methanolic extract of betel leaves from all the selected regions except from Bau exhibited antimicrobial activities. Among them, extract from Kuching and Simunjan have no effect on E. coli. The methanolic extract of curry leaves from Kuching, Balai ringai and Bau have antimicrobial activities against Staph aureus and those from Balai ringai is also active against E.coli. Conclusion: Although there were previous reports of phytochemical screening and antimicrobial activities from the extract of these plants, there were still lack of research conducted on the specimens especially from our local community (Sarawak). The outcome of this study will help us to identify the bioactive compounds of the local samples and give us some pictures of their activities on how to ensure these plants can be brought forward based on the origin of the sample.
format	Article
author	Khin, Than Yee Mohamad Iswandy, Ibrahim Tin, Moe Nwe Mya, Mya Thwin Mar, Mar Lwin Khin, Cho Aung Ma, Saung Oo Siti Zaleha, Raduan Myat, San Yi
author_facet	Khin, Than Yee Mohamad Iswandy, Ibrahim Tin, Moe Nwe Mya, Mya Thwin Mar, Mar Lwin Khin, Cho Aung Ma, Saung Oo Siti Zaleha, Raduan Myat, San Yi
author_sort	Khin, Than Yee
title	Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves)
title_short	Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves)
title_full	Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves)
title_fullStr	Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves)
title_full_unstemmed	Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves)
title_sort	bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : piper betle and murraya koenigii (curry leaves)
publisher	RJPT
publishDate	2023
url	http://ir.unimas.my/id/eprint/41824/2/Bio1.pdf http://ir.unimas.my/id/eprint/41824/ https://www.rjptonline.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20Pharmacy%20and%20Technology;PID=2023-16-3-75
_version_	1767209877964324864
score	13.211869

Bioactive compounds screening, antimicrobial activities of leave extract from two palatable plants : Piper betle and Murraya koenigii (Curry leaves)

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