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Prediction of Drug Concentration in Human Bloodstream using AdamsBashforth-Moulton Method

Pharmaceutical drugs are chemicals intended to avoid, assess, heal, or cure a disease. It is also commonly referred to as medication. When medicine is taken, it gets absorbed into the bloodstream, spreads throughout the body, and achieves its maximum concentration. Following this, the medication lev...

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Main Authors: Farah Liyana, Azizan, Saratha, Sathasivam, Muraly, Velavan, Nur Rusyidah, Azri, Nur Iffah Rafhanah, Abdul Manaf
Format: Article
Language:English
Published: Semarak Ilmu Publishing 2023
Subjects:
QA Mathematics
Online Access:http://ir.unimas.my/id/eprint/41675/1/Prediction%20of%20Drug.pdf
http://ir.unimas.my/id/eprint/41675/
https://semarakilmu.com.my/journals/index.php/applied_sciences_eng_tech/article/view/1369
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spelling my.unimas.ir.416752023-04-13T03:02:40Z http://ir.unimas.my/id/eprint/41675/ Prediction of Drug Concentration in Human Bloodstream using AdamsBashforth-Moulton Method Farah Liyana, Azizan Saratha, Sathasivam Muraly, Velavan Nur Rusyidah, Azri Nur Iffah Rafhanah, Abdul Manaf QA Mathematics Pharmaceutical drugs are chemicals intended to avoid, assess, heal, or cure a disease. It is also commonly referred to as medication. When medicine is taken, it gets absorbed into the bloodstream, spreads throughout the body, and achieves its maximum concentration. Following this, the medication level gradually decreases as it is removed from the body. The drug concentration according to the time can be predicted using mathematical concepts and pharmacokinetic models. The compartmental model is a fundamental type of model used in pharmacokinetics. The number of compartments required to describe the drug's action in the body is one-compartment, twocompartment, and multicompartment. These models can forecast medication concentrations in the body over time. This paper will focus on the one-compartment model and Adams Bashforth-Moulton method. Adams Method is one of the linear multistep techniques applied to solve numerical ordinary differential equations that contain the predictor method (Adams Bashforth) and corrector method (Adams Moulton). The integrated development environment used for the computation and graphing is MATLAB. The expected result of this report is that we can predict the concentration of the chosen drugs over time and how long a particular person needs to wait before donating blood safely. Semarak Ilmu Publishing 2023 Article PeerReviewed text en http://ir.unimas.my/id/eprint/41675/1/Prediction%20of%20Drug.pdf Farah Liyana, Azizan and Saratha, Sathasivam and Muraly, Velavan and Nur Rusyidah, Azri and Nur Iffah Rafhanah, Abdul Manaf (2023) Prediction of Drug Concentration in Human Bloodstream using AdamsBashforth-Moulton Method. Journal of Advanced Research in Applied Sciences and Engineering Technology, 29 (2). pp. 53-71. ISSN 2462-1943 https://semarakilmu.com.my/journals/index.php/applied_sciences_eng_tech/article/view/1369 DOI: https://doi.org/10.37934/araset.29.2.5371
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic QA Mathematics
spellingShingle QA Mathematics
Farah Liyana, Azizan
Saratha, Sathasivam
Muraly, Velavan
Nur Rusyidah, Azri
Nur Iffah Rafhanah, Abdul Manaf
Prediction of Drug Concentration in Human Bloodstream using AdamsBashforth-Moulton Method
description Pharmaceutical drugs are chemicals intended to avoid, assess, heal, or cure a disease. It is also commonly referred to as medication. When medicine is taken, it gets absorbed into the bloodstream, spreads throughout the body, and achieves its maximum concentration. Following this, the medication level gradually decreases as it is removed from the body. The drug concentration according to the time can be predicted using mathematical concepts and pharmacokinetic models. The compartmental model is a fundamental type of model used in pharmacokinetics. The number of compartments required to describe the drug's action in the body is one-compartment, twocompartment, and multicompartment. These models can forecast medication concentrations in the body over time. This paper will focus on the one-compartment model and Adams Bashforth-Moulton method. Adams Method is one of the linear multistep techniques applied to solve numerical ordinary differential equations that contain the predictor method (Adams Bashforth) and corrector method (Adams Moulton). The integrated development environment used for the computation and graphing is MATLAB. The expected result of this report is that we can predict the concentration of the chosen drugs over time and how long a particular person needs to wait before donating blood safely.
format Article
author Farah Liyana, Azizan
Saratha, Sathasivam
Muraly, Velavan
Nur Rusyidah, Azri
Nur Iffah Rafhanah, Abdul Manaf
author_facet Farah Liyana, Azizan
Saratha, Sathasivam
Muraly, Velavan
Nur Rusyidah, Azri
Nur Iffah Rafhanah, Abdul Manaf
author_sort Farah Liyana, Azizan
title Prediction of Drug Concentration in Human Bloodstream using AdamsBashforth-Moulton Method
title_short Prediction of Drug Concentration in Human Bloodstream using AdamsBashforth-Moulton Method
title_full Prediction of Drug Concentration in Human Bloodstream using AdamsBashforth-Moulton Method
title_fullStr Prediction of Drug Concentration in Human Bloodstream using AdamsBashforth-Moulton Method
title_full_unstemmed Prediction of Drug Concentration in Human Bloodstream using AdamsBashforth-Moulton Method
title_sort prediction of drug concentration in human bloodstream using adamsbashforth-moulton method
publisher Semarak Ilmu Publishing
publishDate 2023
url http://ir.unimas.my/id/eprint/41675/1/Prediction%20of%20Drug.pdf
http://ir.unimas.my/id/eprint/41675/
https://semarakilmu.com.my/journals/index.php/applied_sciences_eng_tech/article/view/1369
_version_ 1763300204192202752
score 13.211869

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