Staff View: Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002

Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006)

Background: The Virology Unit, Institute for Medical Research (IMR), Kuala Lumpur has been designated as the National influenza Centre since 1968, carrying out influenza surveillance activities for the Ministry of Health Malaysia. These activities are important for preparation of epidemics and pan...

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Main Authors:	T.R.T., Rashid, Z., Saat, M.A., Yusof, S.J., Berendam, F.Md., Kassim, K.A., Othman, S.K., Lau, N.S., Khairullah, Samuel, Lihan
Format:	Article
Language:	English
Published:	Elsevier Inc. 2008
Subjects:	QR355 Virology
Online Access:	http://ir.unimas.my/id/eprint/40936/1/2008_Surveillance%20Influenzae.pdf http://ir.unimas.my/id/eprint/40936/ https://www.ijidonline.com/article/S1201-9712(08)00939-9/fulltext
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spelling	my.unimas.ir.409362022-12-20T00:46:03Z http://ir.unimas.my/id/eprint/40936/ Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006) T.R.T., Rashid Z., Saat M.A., Yusof S.J., Berendam F.Md., Kassim K.A., Othman S.K., Lau N.S., Khairullah Samuel, Lihan QR355 Virology Background: The Virology Unit, Institute for Medical Research (IMR), Kuala Lumpur has been designated as the National influenza Centre since 1968, carrying out influenza surveillance activities for the Ministry of Health Malaysia. These activities are important for preparation of epidemics and pandemics. In the past decade, several outbreaks of influenza B have been reported in this country. Thus, the aims of this study are to evaluate the incidence and to identify the circulating viral strain of influenza type B in Malaysia. Methods: All respiratory specimens received from several sentinel sites from patients presenting with influenza-like illness (ILI) were included in this study. The virus was detected by culture method using Madin Darby Canine Kidney (MDCK) cells with combination of Immunofluorescence (IF) and haemagglutination inhibition (HAI) techniques. Results: From 2002 to 2006 the National Influenza Centre, IMR received a total of 5,463 specimens from patients presenting with ILI. Of these, 220 (4.0%) were found to be positive for Influenza B virus and further analysis showed that there were four major strains circulating in Malaysia during the five years study period. The predominant strain in 2002 was B/Hong Kong/330/2001-like virus,B/Sichuan/379/99-like virus in 2003, B/Shanghai/361/2002-like virus in 2004, B/Hong Kong/330/2001-like virus in 2005 and B/Malaysia/2506/2004-like virus in 2006. Conclusion: The surveillance activities are not only important as an early warning for outbreak preparedness but also important in detecting new strains that can be used in the annual vaccine formulation. Elsevier Inc. 2008 Article PeerReviewed text en http://ir.unimas.my/id/eprint/40936/1/2008_Surveillance%20Influenzae.pdf T.R.T., Rashid and Z., Saat and M.A., Yusof and S.J., Berendam and F.Md., Kassim and K.A., Othman and S.K., Lau and N.S., Khairullah and Samuel, Lihan (2008) Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006). International Journal of Infectious Diseases, 12 (Supp.1). e302-e302. ISSN 1201-9712 https://www.ijidonline.com/article/S1201-9712(08)00939-9/fulltext doi:10.1016/j.ijid.2008.05.808
institution	Universiti Malaysia Sarawak
building	Centre for Academic Information Services (CAIS)
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Sarawak
content_source	UNIMAS Institutional Repository
url_provider	http://ir.unimas.my/
language	English
topic	QR355 Virology
spellingShingle	QR355 Virology T.R.T., Rashid Z., Saat M.A., Yusof S.J., Berendam F.Md., Kassim K.A., Othman S.K., Lau N.S., Khairullah Samuel, Lihan Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006)
description	Background: The Virology Unit, Institute for Medical Research (IMR), Kuala Lumpur has been designated as the National influenza Centre since 1968, carrying out influenza surveillance activities for the Ministry of Health Malaysia. These activities are important for preparation of epidemics and pandemics. In the past decade, several outbreaks of influenza B have been reported in this country. Thus, the aims of this study are to evaluate the incidence and to identify the circulating viral strain of influenza type B in Malaysia. Methods: All respiratory specimens received from several sentinel sites from patients presenting with influenza-like illness (ILI) were included in this study. The virus was detected by culture method using Madin Darby Canine Kidney (MDCK) cells with combination of Immunofluorescence (IF) and haemagglutination inhibition (HAI) techniques. Results: From 2002 to 2006 the National Influenza Centre, IMR received a total of 5,463 specimens from patients presenting with ILI. Of these, 220 (4.0%) were found to be positive for Influenza B virus and further analysis showed that there were four major strains circulating in Malaysia during the five years study period. The predominant strain in 2002 was B/Hong Kong/330/2001-like virus,B/Sichuan/379/99-like virus in 2003, B/Shanghai/361/2002-like virus in 2004, B/Hong Kong/330/2001-like virus in 2005 and B/Malaysia/2506/2004-like virus in 2006. Conclusion: The surveillance activities are not only important as an early warning for outbreak preparedness but also important in detecting new strains that can be used in the annual vaccine formulation.
format	Article
author	T.R.T., Rashid Z., Saat M.A., Yusof S.J., Berendam F.Md., Kassim K.A., Othman S.K., Lau N.S., Khairullah Samuel, Lihan
author_facet	T.R.T., Rashid Z., Saat M.A., Yusof S.J., Berendam F.Md., Kassim K.A., Othman S.K., Lau N.S., Khairullah Samuel, Lihan
author_sort	T.R.T., Rashid
title	Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006)
title_short	Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006)
title_full	Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006)
title_fullStr	Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006)
title_full_unstemmed	Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006)
title_sort	surveillance of influenza b virus strains circulating in malaysia (2002—2006)
publisher	Elsevier Inc.
publishDate	2008
url	http://ir.unimas.my/id/eprint/40936/1/2008_Surveillance%20Influenzae.pdf http://ir.unimas.my/id/eprint/40936/ https://www.ijidonline.com/article/S1201-9712(08)00939-9/fulltext
_version_	1753792659675152384
score	13.211869

Surveillance of Influenza B Virus Strains Circulating in Malaysia (2002—2006)

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