WATER BOLUS MODIFICATION FOR REDUCING UNWANTED HOT SPOTS FOR BREAST HYPERTHERMIA CANCER PROCEDURE
Hyperthermia Treatment Procedure (HTP) is a method that raises the temperature between 410 -460C, which then denaturate cancer tissue into necrotic tissue. However, due to the poor penetration depth and difficulty in controlling focus position distance to the treated tissue, the HTP success ra...
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Universiti Malaysia Sarawak
2022
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my.unimas.ir.394652022-09-02T03:12:02Z http://ir.unimas.my/id/eprint/39465/ WATER BOLUS MODIFICATION FOR REDUCING UNWANTED HOT SPOTS FOR BREAST HYPERTHERMIA CANCER PROCEDURE NURUL SYAMIMI HANIM BINTI NORAINI, - TK Electrical engineering. Electronics Nuclear engineering Hyperthermia Treatment Procedure (HTP) is a method that raises the temperature between 410 -460C, which then denaturate cancer tissue into necrotic tissue. However, due to the poor penetration depth and difficulty in controlling focus position distance to the treated tissue, the HTP success rate is still low. In conjunction with that, many kinds of research are conducted in order to overcome the matters involved with penetration depth and focus position distance. HTP has fewer side effects, but since HTP utilizes high heat in its procedure towards the treated cancer tissue, it may lead to massive skin burn problems. Therefore, in this research, a modified water bolus is developed in order to provide a cooling environment during HTP execution. Nevertheless, the addition of the water bolus, it may reshape the focus position distance. Hence, a modification of water bolus is significant in ensuring not only reducing the skin burn problem, at the same time, the penetration depth and focus position distance on the treated tissue can be fully provided with a minimal area of unwanted hot spots at surrounding healthy tissue. SEMCAD X is used to model a breast phantom, which consists of breast fat and breast cancer. It is also used to model the microstrip antenna that is used as an HTP applicator and to model the water bolus. Then, the simulation to attain the Specific Absorption Rate (SAR) is also carried out by using SEMCAD X. The SAR represented the penetration depth and focus position distance on the treated tissue. Based on the simulation results, adding the rectangular water bolus with distilled has presented the best penetration depth and focus position distance towards the treated tissue. Furthermore, the unwanted hot spots in surrounding healthy tissue also have been reduced. However, there are some recommendations that need to take into account, especially in providing more investigation in terms of water bolus cover materials, other coolant fluids and water bolus hardware fabrication to further observe the impact of adding the water bolus to the treatment procedure. Universiti Malaysia Sarawak 2022 Final Year Project Report NonPeerReviewed text en http://ir.unimas.my/id/eprint/39465/1/Nurul%20Syamimi%20Hanim%20binti%20Noraini%20%20-%20%2024pages.pdf text en http://ir.unimas.my/id/eprint/39465/2/Nurul%20Syamimi%20Hanim%20binti%20Noraini%20-%20fulltext.pdf NURUL SYAMIMI HANIM BINTI NORAINI, - (2022) WATER BOLUS MODIFICATION FOR REDUCING UNWANTED HOT SPOTS FOR BREAST HYPERTHERMIA CANCER PROCEDURE. [Final Year Project Report] (Unpublished) |
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TK Electrical engineering. Electronics Nuclear engineering NURUL SYAMIMI HANIM BINTI NORAINI, - WATER BOLUS MODIFICATION FOR REDUCING UNWANTED HOT SPOTS FOR BREAST HYPERTHERMIA CANCER PROCEDURE |
| description |
Hyperthermia Treatment Procedure (HTP) is a method that raises the temperature
between 410
-460C, which then denaturate cancer tissue into necrotic tissue. However, due
to the poor penetration depth and difficulty in controlling focus position distance to the
treated tissue, the HTP success rate is still low. In conjunction with that, many kinds of
research are conducted in order to overcome the matters involved with penetration depth
and focus position distance. HTP has fewer side effects, but since HTP utilizes high heat
in its procedure towards the treated cancer tissue, it may lead to massive skin burn
problems. Therefore, in this research, a modified water bolus is developed in order to
provide a cooling environment during HTP execution. Nevertheless, the addition of the
water bolus, it may reshape the focus position distance. Hence, a modification of water
bolus is significant in ensuring not only reducing the skin burn problem, at the same time,
the penetration depth and focus position distance on the treated tissue can be fully
provided with a minimal area of unwanted hot spots at surrounding healthy tissue.
SEMCAD X is used to model a breast phantom, which consists of breast fat and breast
cancer. It is also used to model the microstrip antenna that is used as an HTP applicator
and to model the water bolus. Then, the simulation to attain the Specific Absorption Rate
(SAR) is also carried out by using SEMCAD X. The SAR represented the penetration
depth and focus position distance on the treated tissue. Based on the simulation results,
adding the rectangular water bolus with distilled has presented the best penetration depth
and focus position distance towards the treated tissue. Furthermore, the unwanted hot
spots in surrounding healthy tissue also have been reduced. However, there are some
recommendations that need to take into account, especially in providing more
investigation in terms of water bolus cover materials, other coolant fluids and water bolus
hardware fabrication to further observe the impact of adding the water bolus to the
treatment procedure. |
| format |
Final Year Project Report |
| author |
NURUL SYAMIMI HANIM BINTI NORAINI, - |
| author_facet |
NURUL SYAMIMI HANIM BINTI NORAINI, - |
| author_sort |
NURUL SYAMIMI HANIM BINTI NORAINI, - |
| title |
WATER BOLUS MODIFICATION FOR REDUCING
UNWANTED HOT SPOTS FOR BREAST HYPERTHERMIA
CANCER PROCEDURE |
| title_short |
WATER BOLUS MODIFICATION FOR REDUCING
UNWANTED HOT SPOTS FOR BREAST HYPERTHERMIA
CANCER PROCEDURE |
| title_full |
WATER BOLUS MODIFICATION FOR REDUCING
UNWANTED HOT SPOTS FOR BREAST HYPERTHERMIA
CANCER PROCEDURE |
| title_fullStr |
WATER BOLUS MODIFICATION FOR REDUCING
UNWANTED HOT SPOTS FOR BREAST HYPERTHERMIA
CANCER PROCEDURE |
| title_full_unstemmed |
WATER BOLUS MODIFICATION FOR REDUCING
UNWANTED HOT SPOTS FOR BREAST HYPERTHERMIA
CANCER PROCEDURE |
| title_sort |
water bolus modification for reducing
unwanted hot spots for breast hyperthermia
cancer procedure |
| publisher |
Universiti Malaysia Sarawak |
| publishDate |
2022 |
| url |
http://ir.unimas.my/id/eprint/39465/1/Nurul%20Syamimi%20Hanim%20binti%20Noraini%20%20-%20%2024pages.pdf http://ir.unimas.my/id/eprint/39465/2/Nurul%20Syamimi%20Hanim%20binti%20Noraini%20-%20fulltext.pdf http://ir.unimas.my/id/eprint/39465/ |
| _version_ |
1743110968968216576 |
| score |
13.211869 |