Recent Advances in Honey-Based Nanoparticles for Wound Dressing: A Review

Wounds with impaired healing, including delayed acute injuries and chronic injuries, generally fail to progress through normal healing stages. A deeper understanding of the biochemical processes involved in chronic wound cures is necessary to correct the microenvironmental imbalances in the wound tr...

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Main Authors: Norfarina, Bahari, Norhashila, Hashim, Abdah, Md Akim, Bernard, Maringgal
Format: Article
Language:English
Published: MDPI 2022
Subjects:
Online Access:http://ir.unimas.my/id/eprint/39216/2/Recent%20Advances%20-%20Copy.pdf
http://ir.unimas.my/id/eprint/39216/
https://www.mdpi.com/2079-4991/12/15/2560
https://doi.org/10.3390/nano12152560
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spelling my.unimas.ir.392162022-08-16T02:30:09Z http://ir.unimas.my/id/eprint/39216/ Recent Advances in Honey-Based Nanoparticles for Wound Dressing: A Review Norfarina, Bahari Norhashila, Hashim Abdah, Md Akim Bernard, Maringgal Q Science (General) R Medicine (General) S Agriculture (General) T Technology (General) Wounds with impaired healing, including delayed acute injuries and chronic injuries, generally fail to progress through normal healing stages. A deeper understanding of the biochemical processes involved in chronic wound cures is necessary to correct the microenvironmental imbalances in the wound treatment designs of products. The therapeutic benefits of honey, particularly its antimicrobial activity, make it a viable option for wound treatment in a variety of situations. Integration with nanotechnology has opened up new possibilities not only for wound healing but also for other medicinal applications. In this review, recent advances in honey-based nanoparticles for wound healing are discussed. This also covers the mechanism of the action of nanoparticles in the wound healing process and perspectives on the challenges and future trends of using honey based nanoparticles. The underlying mechanisms of wound healing using honey are believed to be attributed to hydrogen peroxide, high osmolality, acidity, non-peroxide components, and phenols. Therefore, incorporating honey into various wound dressings has become a major trend due to the increasing demand for combination dressings in the global wound dressing market because these dressings contain two or more types of chemical and physical properties to ensure optimal functionality. At the same time, their multiple features (low cost, biocompatibility, and swelling index) and diverse fabrication methods (electrospun fibres, hydrogels, etc.) make them a popular choice among researchers. MDPI 2022-07-26 Article PeerReviewed text en http://ir.unimas.my/id/eprint/39216/2/Recent%20Advances%20-%20Copy.pdf Norfarina, Bahari and Norhashila, Hashim and Abdah, Md Akim and Bernard, Maringgal (2022) Recent Advances in Honey-Based Nanoparticles for Wound Dressing: A Review. Nanomaterials, 12 (15). pp. 1-19. ISSN 2079-4991 https://www.mdpi.com/2079-4991/12/15/2560 https://doi.org/10.3390/nano12152560
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic Q Science (General)
R Medicine (General)
S Agriculture (General)
T Technology (General)
spellingShingle Q Science (General)
R Medicine (General)
S Agriculture (General)
T Technology (General)
Norfarina, Bahari
Norhashila, Hashim
Abdah, Md Akim
Bernard, Maringgal
Recent Advances in Honey-Based Nanoparticles for Wound Dressing: A Review
description Wounds with impaired healing, including delayed acute injuries and chronic injuries, generally fail to progress through normal healing stages. A deeper understanding of the biochemical processes involved in chronic wound cures is necessary to correct the microenvironmental imbalances in the wound treatment designs of products. The therapeutic benefits of honey, particularly its antimicrobial activity, make it a viable option for wound treatment in a variety of situations. Integration with nanotechnology has opened up new possibilities not only for wound healing but also for other medicinal applications. In this review, recent advances in honey-based nanoparticles for wound healing are discussed. This also covers the mechanism of the action of nanoparticles in the wound healing process and perspectives on the challenges and future trends of using honey based nanoparticles. The underlying mechanisms of wound healing using honey are believed to be attributed to hydrogen peroxide, high osmolality, acidity, non-peroxide components, and phenols. Therefore, incorporating honey into various wound dressings has become a major trend due to the increasing demand for combination dressings in the global wound dressing market because these dressings contain two or more types of chemical and physical properties to ensure optimal functionality. At the same time, their multiple features (low cost, biocompatibility, and swelling index) and diverse fabrication methods (electrospun fibres, hydrogels, etc.) make them a popular choice among researchers.
format Article
author Norfarina, Bahari
Norhashila, Hashim
Abdah, Md Akim
Bernard, Maringgal
author_facet Norfarina, Bahari
Norhashila, Hashim
Abdah, Md Akim
Bernard, Maringgal
author_sort Norfarina, Bahari
title Recent Advances in Honey-Based Nanoparticles for Wound Dressing: A Review
title_short Recent Advances in Honey-Based Nanoparticles for Wound Dressing: A Review
title_full Recent Advances in Honey-Based Nanoparticles for Wound Dressing: A Review
title_fullStr Recent Advances in Honey-Based Nanoparticles for Wound Dressing: A Review
title_full_unstemmed Recent Advances in Honey-Based Nanoparticles for Wound Dressing: A Review
title_sort recent advances in honey-based nanoparticles for wound dressing: a review
publisher MDPI
publishDate 2022
url http://ir.unimas.my/id/eprint/39216/2/Recent%20Advances%20-%20Copy.pdf
http://ir.unimas.my/id/eprint/39216/
https://www.mdpi.com/2079-4991/12/15/2560
https://doi.org/10.3390/nano12152560
_version_ 1743110939954118656
score 13.211869