Quantification of multi-classes of endocrine-disrupting compounds in estuarine water

Emerging pollutants known as endocrine-disrupting compounds (EDCs) are a contemporary global issue, especially in aquatic ecosystems. As aquaculture production through mariculture activities in Malaysia supports food production, the concentration and distribution of EDCs in estuarine water ecosyst...

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Main Authors: Nur Afifah Hanun, Ismail, Sze Yee, Wee, Nitty Hirawaty, Kamarulzaman, Ahmad Zaharin, Aris
Format: Article
Language:English
Published: Elsevier 2019
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Online Access:http://ir.unimas.my/id/eprint/39145/1/Quantification%20of%20multi-classes%20of%20endocrine-disrupting.pdf
http://ir.unimas.my/id/eprint/39145/
https://www.sciencedirect.com/science/article/abs/pii/S0269749119301848
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spelling my.unimas.ir.391452023-03-31T04:02:51Z http://ir.unimas.my/id/eprint/39145/ Quantification of multi-classes of endocrine-disrupting compounds in estuarine water Nur Afifah Hanun, Ismail Sze Yee, Wee Nitty Hirawaty, Kamarulzaman Ahmad Zaharin, Aris GE Environmental Sciences HD61 Risk Management Emerging pollutants known as endocrine-disrupting compounds (EDCs) are a contemporary global issue, especially in aquatic ecosystems. As aquaculture production through mariculture activities in Malaysia supports food production, the concentration and distribution of EDCs in estuarine water ecosystems may have changed. Therefore, this current study aims to prepare a suitable and reliable method for application on environmental samples. Besides, this study also presented the occurrence of EDCs pollutant in Pulau Kukup, Johor, where the biggest and most active mariculture site in Malaysia takes place. Analytical methods based on a combination of solid-phase extraction with liquid chromatography tandem mass spectrometry (Solid-phase extraction (SPE)-LC-MS/MS) have been modified and optimised to examine the level of targeted EDCs contaminant. In the current study, this method displays high extraction recovery for targeted EDCs, ranging from 92.02% to 132.32%. The highest concentration detected is diclofenac (<0.47e79.89 ng/L) followed by 17b-estradiol (E2) (<5.28e31.43 ng/L) and 17a-ethynylestradiol (EE2) (<0.30e7.67 ng/L). The highest percentage distribution for the targeted EDCs in the current study is diclofenac, followed by EE2 and dexamethasone with the percentages of 99.44%, 89.53% and 73.23%, respectively. This current study can be a baseline assessment to understand the pollution profile of EDCs and their distribution in the estuarine water of the mariculture site throughout the world, especially in Malaysia. Owing to the significant concentration of targeted EDCs detected in water samples, the need for further monitoring in the future is required. Elsevier 2019-06 Article PeerReviewed text en http://ir.unimas.my/id/eprint/39145/1/Quantification%20of%20multi-classes%20of%20endocrine-disrupting.pdf Nur Afifah Hanun, Ismail and Sze Yee, Wee and Nitty Hirawaty, Kamarulzaman and Ahmad Zaharin, Aris (2019) Quantification of multi-classes of endocrine-disrupting compounds in estuarine water. Environmental Pollution, 249. pp. 1019-1028. ISSN 0269-7491 https://www.sciencedirect.com/science/article/abs/pii/S0269749119301848 10.1016/j.envpol.2019.03.089
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic GE Environmental Sciences
HD61 Risk Management
spellingShingle GE Environmental Sciences
HD61 Risk Management
Nur Afifah Hanun, Ismail
Sze Yee, Wee
Nitty Hirawaty, Kamarulzaman
Ahmad Zaharin, Aris
Quantification of multi-classes of endocrine-disrupting compounds in estuarine water
description Emerging pollutants known as endocrine-disrupting compounds (EDCs) are a contemporary global issue, especially in aquatic ecosystems. As aquaculture production through mariculture activities in Malaysia supports food production, the concentration and distribution of EDCs in estuarine water ecosystems may have changed. Therefore, this current study aims to prepare a suitable and reliable method for application on environmental samples. Besides, this study also presented the occurrence of EDCs pollutant in Pulau Kukup, Johor, where the biggest and most active mariculture site in Malaysia takes place. Analytical methods based on a combination of solid-phase extraction with liquid chromatography tandem mass spectrometry (Solid-phase extraction (SPE)-LC-MS/MS) have been modified and optimised to examine the level of targeted EDCs contaminant. In the current study, this method displays high extraction recovery for targeted EDCs, ranging from 92.02% to 132.32%. The highest concentration detected is diclofenac (<0.47e79.89 ng/L) followed by 17b-estradiol (E2) (<5.28e31.43 ng/L) and 17a-ethynylestradiol (EE2) (<0.30e7.67 ng/L). The highest percentage distribution for the targeted EDCs in the current study is diclofenac, followed by EE2 and dexamethasone with the percentages of 99.44%, 89.53% and 73.23%, respectively. This current study can be a baseline assessment to understand the pollution profile of EDCs and their distribution in the estuarine water of the mariculture site throughout the world, especially in Malaysia. Owing to the significant concentration of targeted EDCs detected in water samples, the need for further monitoring in the future is required.
format Article
author Nur Afifah Hanun, Ismail
Sze Yee, Wee
Nitty Hirawaty, Kamarulzaman
Ahmad Zaharin, Aris
author_facet Nur Afifah Hanun, Ismail
Sze Yee, Wee
Nitty Hirawaty, Kamarulzaman
Ahmad Zaharin, Aris
author_sort Nur Afifah Hanun, Ismail
title Quantification of multi-classes of endocrine-disrupting compounds in estuarine water
title_short Quantification of multi-classes of endocrine-disrupting compounds in estuarine water
title_full Quantification of multi-classes of endocrine-disrupting compounds in estuarine water
title_fullStr Quantification of multi-classes of endocrine-disrupting compounds in estuarine water
title_full_unstemmed Quantification of multi-classes of endocrine-disrupting compounds in estuarine water
title_sort quantification of multi-classes of endocrine-disrupting compounds in estuarine water
publisher Elsevier
publishDate 2019
url http://ir.unimas.my/id/eprint/39145/1/Quantification%20of%20multi-classes%20of%20endocrine-disrupting.pdf
http://ir.unimas.my/id/eprint/39145/
https://www.sciencedirect.com/science/article/abs/pii/S0269749119301848
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score 13.211869