Anencephaly is a complicated and perplexing situation

Anencephaly means simply no brain or acrania. To be precise, it is a congenital absence of the skull, scalp, and forebrain (cerebral hemispheres). It was categorized under neural tube defects (NTD). As a whole, NTD is the second most common fatal anomaly after cardiac defects. The neural tube defect...

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Main Authors: Soe, Lwin, Tin Moe, Nwe, Khin Than, Yee, Myat, San Yi
Format: Article
Language:English
Published: A and v publication 2022
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Online Access:http://ir.unimas.my/id/eprint/38602/3/Anencephaly%20-%20Copy.pdf
http://ir.unimas.my/id/eprint/38602/
https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-5-29
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spelling my.unimas.ir.386022022-06-03T02:53:42Z http://ir.unimas.my/id/eprint/38602/ Anencephaly is a complicated and perplexing situation Soe, Lwin Tin Moe, Nwe Khin Than, Yee Myat, San Yi RG Gynecology and obstetrics Anencephaly means simply no brain or acrania. To be precise, it is a congenital absence of the skull, scalp, and forebrain (cerebral hemispheres). It was categorized under neural tube defects (NTD). As a whole, NTD is the second most common fatal anomaly after cardiac defects. The neural tube defects are a group of central nervous system ailments, which result from the failure of normal primary neurulation, an embryologic process completes in humans by almost day 26-28 the post- conception. In this case, the normal closure of the anterior neuropore fails, which results in anencephaly. The case report demonstrates the clinical experience that would broaden our knowledge of this uncommon but distressing and dilemmatic event. We highlighted the ultrasound features to recognize the condition by first and second-trimester scans and the role of folic acid in the prevention of further occurrence. The diagnosis was confirmed anencephaly with formal ultrasound from the radiologist, who reported no definite brain parenchyma noted, the head was small in size, and the patient was informed about the condition and its prognosis. The reported case was found to be rare and clinicians emphasized the contribution of professional guidance for its management since the case is critical and the ethical concerns need careful handling to avoid adverse psychosocial outcomes such as grief, guilt, anxiety, and loss of self-confidence. KEYWORDS: Anencephaly, Neural tube defect, Folic acid A and v publication 2022-06 Article PeerReviewed text en http://ir.unimas.my/id/eprint/38602/3/Anencephaly%20-%20Copy.pdf Soe, Lwin and Tin Moe, Nwe and Khin Than, Yee and Myat, San Yi (2022) Anencephaly is a complicated and perplexing situation. Research Journal of Pharmacy and Technology, 15 (5). pp. 2097-2099. ISSN 0974-360X (Online) https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-5-29 10.52711/0974-360X.2022.00347
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic RG Gynecology and obstetrics
spellingShingle RG Gynecology and obstetrics
Soe, Lwin
Tin Moe, Nwe
Khin Than, Yee
Myat, San Yi
Anencephaly is a complicated and perplexing situation
description Anencephaly means simply no brain or acrania. To be precise, it is a congenital absence of the skull, scalp, and forebrain (cerebral hemispheres). It was categorized under neural tube defects (NTD). As a whole, NTD is the second most common fatal anomaly after cardiac defects. The neural tube defects are a group of central nervous system ailments, which result from the failure of normal primary neurulation, an embryologic process completes in humans by almost day 26-28 the post- conception. In this case, the normal closure of the anterior neuropore fails, which results in anencephaly. The case report demonstrates the clinical experience that would broaden our knowledge of this uncommon but distressing and dilemmatic event. We highlighted the ultrasound features to recognize the condition by first and second-trimester scans and the role of folic acid in the prevention of further occurrence. The diagnosis was confirmed anencephaly with formal ultrasound from the radiologist, who reported no definite brain parenchyma noted, the head was small in size, and the patient was informed about the condition and its prognosis. The reported case was found to be rare and clinicians emphasized the contribution of professional guidance for its management since the case is critical and the ethical concerns need careful handling to avoid adverse psychosocial outcomes such as grief, guilt, anxiety, and loss of self-confidence. KEYWORDS: Anencephaly, Neural tube defect, Folic acid
format Article
author Soe, Lwin
Tin Moe, Nwe
Khin Than, Yee
Myat, San Yi
author_facet Soe, Lwin
Tin Moe, Nwe
Khin Than, Yee
Myat, San Yi
author_sort Soe, Lwin
title Anencephaly is a complicated and perplexing situation
title_short Anencephaly is a complicated and perplexing situation
title_full Anencephaly is a complicated and perplexing situation
title_fullStr Anencephaly is a complicated and perplexing situation
title_full_unstemmed Anencephaly is a complicated and perplexing situation
title_sort anencephaly is a complicated and perplexing situation
publisher A and v publication
publishDate 2022
url http://ir.unimas.my/id/eprint/38602/3/Anencephaly%20-%20Copy.pdf
http://ir.unimas.my/id/eprint/38602/
https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-5-29
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score 13.211869