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SCREENING OF ANTIBACTERIAL ACTIVITY OF NEOLAMARCKIA MACROPHYLLA LEAF CRUDE EXTRACT

Neolamarckia macrophylla (Roxb.) Bosser belongs to genus Neolamarckia of the family Rubiaceae which commonly known as the red kelampayan by the locals. It is an important timber tree that is used for reforestation, the woods used as raw materials of paper and plywood, while its bark used to relive f...

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Main Authors: Fazia, Mohamad Sinang, Michelle, Ngassy Mering, Ho Wei, Seng
Format: Poster
Language:English
English
Published: The Regional Conference and Exhibition on Natural Products, Traditional Medicines and Herbs 2021 2021
Subjects:
Q Science (General)
Online Access:http://ir.unimas.my/id/eprint/37252/1/screening%20of%20antimicrobial%20activity%20of%20N.%20Macrophylla%20crude%20extract.pdf
http://ir.unimas.my/id/eprint/37252/3/Regional%20Conference.pdf
http://ir.unimas.my/id/eprint/37252/
http://www.conference.unimas.my/2021/ktz2021/
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id my.unimas.ir.37252
record_format eprints
spelling my.unimas.ir.372522022-08-30T03:09:04Z http://ir.unimas.my/id/eprint/37252/ SCREENING OF ANTIBACTERIAL ACTIVITY OF NEOLAMARCKIA MACROPHYLLA LEAF CRUDE EXTRACT Fazia, Mohamad Sinang Michelle, Ngassy Mering Ho Wei, Seng Q Science (General) Neolamarckia macrophylla (Roxb.) Bosser belongs to genus Neolamarckia of the family Rubiaceae which commonly known as the red kelampayan by the locals. It is an important timber tree that is used for reforestation, the woods used as raw materials of paper and plywood, while its bark used to relive fever in traditional medicine (Shi et al. 2020; Qalbi et al., 2019). The aim of this study was to determine the antimicrobial potential of N. macrophylla leaf crude extract. The crude extract was obtained using maceration technique using ethanol and distilled water as solvent for the extraction process. The antibacterial activities were screened against Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus and Bacillus cereus with different concentration of the crude extract (12.5 mg/mL, 25 mg/mL, 50 mg/mL and 100 mg/mL) by using disc diffusion method. The test bacteria demonstrated inhibition zone between 7 to 10 mm with the linear increase of inhibition zone with concentration of extract. This findings provide preliminary results on the antibacterial potential of N. Macrophylla to be used in various application. Further purification of compounds might be necessary to explore more on its optimum potential. The Regional Conference and Exhibition on Natural Products, Traditional Medicines and Herbs 2021 2021 Poster NonPeerReviewed text en http://ir.unimas.my/id/eprint/37252/1/screening%20of%20antimicrobial%20activity%20of%20N.%20Macrophylla%20crude%20extract.pdf text en http://ir.unimas.my/id/eprint/37252/3/Regional%20Conference.pdf Fazia, Mohamad Sinang and Michelle, Ngassy Mering and Ho Wei, Seng (2021) SCREENING OF ANTIBACTERIAL ACTIVITY OF NEOLAMARCKIA MACROPHYLLA LEAF CRUDE EXTRACT. [Poster] (Submitted) http://www.conference.unimas.my/2021/ktz2021/
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
English
topic Q Science (General)
spellingShingle Q Science (General)
Fazia, Mohamad Sinang
Michelle, Ngassy Mering
Ho Wei, Seng
SCREENING OF ANTIBACTERIAL ACTIVITY OF NEOLAMARCKIA MACROPHYLLA LEAF CRUDE EXTRACT
description Neolamarckia macrophylla (Roxb.) Bosser belongs to genus Neolamarckia of the family Rubiaceae which commonly known as the red kelampayan by the locals. It is an important timber tree that is used for reforestation, the woods used as raw materials of paper and plywood, while its bark used to relive fever in traditional medicine (Shi et al. 2020; Qalbi et al., 2019). The aim of this study was to determine the antimicrobial potential of N. macrophylla leaf crude extract. The crude extract was obtained using maceration technique using ethanol and distilled water as solvent for the extraction process. The antibacterial activities were screened against Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus and Bacillus cereus with different concentration of the crude extract (12.5 mg/mL, 25 mg/mL, 50 mg/mL and 100 mg/mL) by using disc diffusion method. The test bacteria demonstrated inhibition zone between 7 to 10 mm with the linear increase of inhibition zone with concentration of extract. This findings provide preliminary results on the antibacterial potential of N. Macrophylla to be used in various application. Further purification of compounds might be necessary to explore more on its optimum potential.
format Poster
author Fazia, Mohamad Sinang
Michelle, Ngassy Mering
Ho Wei, Seng
author_facet Fazia, Mohamad Sinang
Michelle, Ngassy Mering
Ho Wei, Seng
author_sort Fazia, Mohamad Sinang
title SCREENING OF ANTIBACTERIAL ACTIVITY OF NEOLAMARCKIA MACROPHYLLA LEAF CRUDE EXTRACT
title_short SCREENING OF ANTIBACTERIAL ACTIVITY OF NEOLAMARCKIA MACROPHYLLA LEAF CRUDE EXTRACT
title_full SCREENING OF ANTIBACTERIAL ACTIVITY OF NEOLAMARCKIA MACROPHYLLA LEAF CRUDE EXTRACT
title_fullStr SCREENING OF ANTIBACTERIAL ACTIVITY OF NEOLAMARCKIA MACROPHYLLA LEAF CRUDE EXTRACT
title_full_unstemmed SCREENING OF ANTIBACTERIAL ACTIVITY OF NEOLAMARCKIA MACROPHYLLA LEAF CRUDE EXTRACT
title_sort screening of antibacterial activity of neolamarckia macrophylla leaf crude extract
publisher The Regional Conference and Exhibition on Natural Products, Traditional Medicines and Herbs 2021
publishDate 2021
url http://ir.unimas.my/id/eprint/37252/1/screening%20of%20antimicrobial%20activity%20of%20N.%20Macrophylla%20crude%20extract.pdf
http://ir.unimas.my/id/eprint/37252/3/Regional%20Conference.pdf
http://ir.unimas.my/id/eprint/37252/
http://www.conference.unimas.my/2021/ktz2021/
_version_ 1743110932248133632
score 13.211869

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