A five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma

Introduction: Juvenile nasopharyngeal angiofibroma (JNA) is a histological benign but locally aggressive vascular tumour which can invade the base of skull. Aim: This is a retrospective study with the aim to examine the outcome of patients with JNA and endoscopic endonasal excision of tumour at a...

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Main Authors: Siew Chung, Cheah, Li Yun, Lim, Salina, Binti Hussain, Ing Ping, Tang
Format: Article
Language:English
Published: Bentus 2021
Subjects:
Online Access:http://ir.unimas.my/id/eprint/36121/1/endoscopic1.pdf
http://ir.unimas.my/id/eprint/36121/
http://www.paom.pl/A-five-year-experience-in-endoscopic-endonasal-excision-of-juvenile-nasopharyngeal,134205,0,2.html
https://doi.org/10.29089/2020.20.00175
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spelling my.unimas.ir.361212021-09-19T02:58:02Z http://ir.unimas.my/id/eprint/36121/ A five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma Siew Chung, Cheah Li Yun, Lim Salina, Binti Hussain Ing Ping, Tang RF Otorhinolaryngology Introduction: Juvenile nasopharyngeal angiofibroma (JNA) is a histological benign but locally aggressive vascular tumour which can invade the base of skull. Aim: This is a retrospective study with the aim to examine the outcome of patients with JNA and endoscopic endonasal excision of tumour at a tertiary center in Malaysia. Material and methods: 9 patients were identified from the medical record office from 2015 to 2019. We review the data on patient demographics, clinical presentations, laboratory investigations, intraoperative blood loss and duration of hospital stay. Results and discussion: 8 patients were male, 1 was female. The average age of diagnosis was 15 (range 11 to 29) years. The commonest chief complaint was recurrent epistaxis, followed by nasal obstruction and nasal discharge. Three patients were at stage I, 4 patients at stage II, 1 patient at stage III and 1 patient at stage IV based on Fisch classification. All patients underwent primary endoscopic endonasal excision of tumour with no vascular, ophthalmological or neurological complication. Seven patients had preoperative embolization done. Average operation time was 137 minutes (range 60–360 minutes). Intraoperative blood lost varied from 500 mL to 1300 mL (mean 777.7 mL). All patients were discharged well with no recurrence. Conclusions: The management of JNA can be challenging. The current shift in management favouring endoscopic endonasal excision of JNA reduces postoperative morbidity. It is possible to be applied on all stages of tumour with good success rate. Bentus 2021-08-24 Article PeerReviewed text en http://ir.unimas.my/id/eprint/36121/1/endoscopic1.pdf Siew Chung, Cheah and Li Yun, Lim and Salina, Binti Hussain and Ing Ping, Tang (2021) A five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma. Polish Annals of Medicine (2021). pp. 1-5. http://www.paom.pl/A-five-year-experience-in-endoscopic-endonasal-excision-of-juvenile-nasopharyngeal,134205,0,2.html https://doi.org/10.29089/2020.20.00175
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic RF Otorhinolaryngology
spellingShingle RF Otorhinolaryngology
Siew Chung, Cheah
Li Yun, Lim
Salina, Binti Hussain
Ing Ping, Tang
A five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma
description Introduction: Juvenile nasopharyngeal angiofibroma (JNA) is a histological benign but locally aggressive vascular tumour which can invade the base of skull. Aim: This is a retrospective study with the aim to examine the outcome of patients with JNA and endoscopic endonasal excision of tumour at a tertiary center in Malaysia. Material and methods: 9 patients were identified from the medical record office from 2015 to 2019. We review the data on patient demographics, clinical presentations, laboratory investigations, intraoperative blood loss and duration of hospital stay. Results and discussion: 8 patients were male, 1 was female. The average age of diagnosis was 15 (range 11 to 29) years. The commonest chief complaint was recurrent epistaxis, followed by nasal obstruction and nasal discharge. Three patients were at stage I, 4 patients at stage II, 1 patient at stage III and 1 patient at stage IV based on Fisch classification. All patients underwent primary endoscopic endonasal excision of tumour with no vascular, ophthalmological or neurological complication. Seven patients had preoperative embolization done. Average operation time was 137 minutes (range 60–360 minutes). Intraoperative blood lost varied from 500 mL to 1300 mL (mean 777.7 mL). All patients were discharged well with no recurrence. Conclusions: The management of JNA can be challenging. The current shift in management favouring endoscopic endonasal excision of JNA reduces postoperative morbidity. It is possible to be applied on all stages of tumour with good success rate.
format Article
author Siew Chung, Cheah
Li Yun, Lim
Salina, Binti Hussain
Ing Ping, Tang
author_facet Siew Chung, Cheah
Li Yun, Lim
Salina, Binti Hussain
Ing Ping, Tang
author_sort Siew Chung, Cheah
title A five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma
title_short A five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma
title_full A five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma
title_fullStr A five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma
title_full_unstemmed A five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma
title_sort five-year experience in endoscopic endonasal excision of juvenile nasopharyngeal angiofibroma
publisher Bentus
publishDate 2021
url http://ir.unimas.my/id/eprint/36121/1/endoscopic1.pdf
http://ir.unimas.my/id/eprint/36121/
http://www.paom.pl/A-five-year-experience-in-endoscopic-endonasal-excision-of-juvenile-nasopharyngeal,134205,0,2.html
https://doi.org/10.29089/2020.20.00175
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