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"Fleshy" Skin Cellulitis: A Triggering Factor for ANCA Associated Vasculitis

A 59-year-old lady with underlying hypothyroidism presented with acute contact dermatitis progressed to cellulitis with superimposed bacterial infection and acute kidney injury. She responded to initial management with antibiotics, but a week later, she had cutaneous and systemic vasculitis. Her ski...

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Main Authors: Sim, Chun Yang, Ruslinda, Mustafar, Lydia, Kamaruzaman, Kong, Wei Yen, Rozita, Mohd, Rizna, Cader
Format: Article
Language:English
Published: MyMedR 2019
Subjects:
R Medicine (General)
RC Internal medicine
Online Access:http://ir.unimas.my/id/eprint/32881/1/Fleshy%20Skin%20Cellulitis%20A%20Triggering%20Factor%20for%20ANCA%20Associated%20Vasculitis_pdf.pdf
http://ir.unimas.my/id/eprint/32881/
https://pubmed.ncbi.nlm.nih.gov/32041918/
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spelling my.unimas.ir.328812020-11-23T07:02:10Z http://ir.unimas.my/id/eprint/32881/ "Fleshy" Skin Cellulitis: A Triggering Factor for ANCA Associated Vasculitis Sim, Chun Yang Ruslinda, Mustafar Lydia, Kamaruzaman Kong, Wei Yen Rozita, Mohd Rizna, Cader R Medicine (General) RC Internal medicine A 59-year-old lady with underlying hypothyroidism presented with acute contact dermatitis progressed to cellulitis with superimposed bacterial infection and acute kidney injury. She responded to initial management with antibiotics, but a week later, she had cutaneous and systemic vasculitis. Her skin biopsy consistent with immune-mediated leuko-cytoclastic vasculitis and her blood test was positive for cytoplasmic-anti-neutrophil cytoplasmic antibody (c-ANCA). A diagnosis of ANCA-associated vasculitis was made and she was treated with immunosuppressant with plasmapheresis and hemodialysis support for her kidney failure. Despite aggressive measures, the patient succumbed to her illness. This case report demonstrates that soft tissue infection could trigger the development of ANCA-associated vasculitis whilst a background of hypothyroidism serves as a predisposing factor as both condition were reported separately in a couple of case studies before. MyMedR 2019-10-01 Article PeerReviewed text en http://ir.unimas.my/id/eprint/32881/1/Fleshy%20Skin%20Cellulitis%20A%20Triggering%20Factor%20for%20ANCA%20Associated%20Vasculitis_pdf.pdf Sim, Chun Yang and Ruslinda, Mustafar and Lydia, Kamaruzaman and Kong, Wei Yen and Rozita, Mohd and Rizna, Cader (2019) "Fleshy" Skin Cellulitis: A Triggering Factor for ANCA Associated Vasculitis. Acta medica Indonesiana, 51 (4). pp. 338-343. ISSN 0125-9326 https://pubmed.ncbi.nlm.nih.gov/32041918/
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic R Medicine (General)
RC Internal medicine
spellingShingle R Medicine (General)
RC Internal medicine
Sim, Chun Yang
Ruslinda, Mustafar
Lydia, Kamaruzaman
Kong, Wei Yen
Rozita, Mohd
Rizna, Cader
"Fleshy" Skin Cellulitis: A Triggering Factor for ANCA Associated Vasculitis
description A 59-year-old lady with underlying hypothyroidism presented with acute contact dermatitis progressed to cellulitis with superimposed bacterial infection and acute kidney injury. She responded to initial management with antibiotics, but a week later, she had cutaneous and systemic vasculitis. Her skin biopsy consistent with immune-mediated leuko-cytoclastic vasculitis and her blood test was positive for cytoplasmic-anti-neutrophil cytoplasmic antibody (c-ANCA). A diagnosis of ANCA-associated vasculitis was made and she was treated with immunosuppressant with plasmapheresis and hemodialysis support for her kidney failure. Despite aggressive measures, the patient succumbed to her illness. This case report demonstrates that soft tissue infection could trigger the development of ANCA-associated vasculitis whilst a background of hypothyroidism serves as a predisposing factor as both condition were reported separately in a couple of case studies before.
format Article
author Sim, Chun Yang
Ruslinda, Mustafar
Lydia, Kamaruzaman
Kong, Wei Yen
Rozita, Mohd
Rizna, Cader
author_facet Sim, Chun Yang
Ruslinda, Mustafar
Lydia, Kamaruzaman
Kong, Wei Yen
Rozita, Mohd
Rizna, Cader
author_sort Sim, Chun Yang
title "Fleshy" Skin Cellulitis: A Triggering Factor for ANCA Associated Vasculitis
title_short "Fleshy" Skin Cellulitis: A Triggering Factor for ANCA Associated Vasculitis
title_full "Fleshy" Skin Cellulitis: A Triggering Factor for ANCA Associated Vasculitis
title_fullStr "Fleshy" Skin Cellulitis: A Triggering Factor for ANCA Associated Vasculitis
title_full_unstemmed "Fleshy" Skin Cellulitis: A Triggering Factor for ANCA Associated Vasculitis
title_sort "fleshy" skin cellulitis: a triggering factor for anca associated vasculitis
publisher MyMedR
publishDate 2019
url http://ir.unimas.my/id/eprint/32881/1/Fleshy%20Skin%20Cellulitis%20A%20Triggering%20Factor%20for%20ANCA%20Associated%20Vasculitis_pdf.pdf
http://ir.unimas.my/id/eprint/32881/
https://pubmed.ncbi.nlm.nih.gov/32041918/
_version_ 1684657082057359360
score 13.211869

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