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Signal change in BA17, 18 and 19: A comparative study of normal, glaucoma suspects and POAGpatients

Magnetic resonance signal change is expected to be different between normal, glaucoma suspect (GS) and Primary Open Angle Glaucoma (POAG) subjects. Functional magnetic resonance imaging (fMRI) technique was employed to investigate the differences. This multiple subject studies were carried out to ch...

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Main Authors: Nurul Hanim, Nasaruddin, A N, Yusoff, Sharanjeet, Kaur
Format: Article
Language:English
Published: IOP Publishing 2020
Subjects:
Q Science (General)
Online Access:http://ir.unimas.my/id/eprint/32639/1/Nasaruddin.pdf
http://ir.unimas.my/id/eprint/32639/
https://iopscience.iop.org/article/10.1088/1742-6596/1497/1/012023
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spelling my.unimas.ir.326392021-04-05T06:55:20Z http://ir.unimas.my/id/eprint/32639/ Signal change in BA17, 18 and 19: A comparative study of normal, glaucoma suspects and POAGpatients Nurul Hanim, Nasaruddin A N, Yusoff Sharanjeet, Kaur Q Science (General) Magnetic resonance signal change is expected to be different between normal, glaucoma suspect (GS) and Primary Open Angle Glaucoma (POAG) subjects. Functional magnetic resonance imaging (fMRI) technique was employed to investigate the differences. This multiple subject studies were carried out to characterize the percentage of signal change (PSC) in Brodmann Area (BA) 17, 18 and 19 of the visual cortex. The block designed fMRI was implemented. The subjects were requested to focus on the black and white checkerboard stimulus of the visual world (A, B and CD), visual field (EF) and visual area (G). The data were analysed using Statistical Parametric Mapping (SPM8) via Matlab platform. results showed that GS subjects have the highest PSC, followed by normal and POAG subjects. However, no significant difference was observed in PSC between BA17, 18 and 19 for normal, GS and POAG groups with p = 0.0869, p = 0.0688 and p = 0.2690, respectively. In conclusion, none of the BA can be suggested to be the most dominant area in responding to the visual stimuli used in this study. IOP Publishing 2020 Article PeerReviewed text en http://ir.unimas.my/id/eprint/32639/1/Nasaruddin.pdf Nurul Hanim, Nasaruddin and A N, Yusoff and Sharanjeet, Kaur (2020) Signal change in BA17, 18 and 19: A comparative study of normal, glaucoma suspects and POAGpatients. Journal of Physics: Conference Series, 1497. pp. 1-4. ISSN 1742-6596 https://iopscience.iop.org/article/10.1088/1742-6596/1497/1/012023 doi:10.1088/1742-6596/1497/1/012023
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic Q Science (General)
spellingShingle Q Science (General)
Nurul Hanim, Nasaruddin
A N, Yusoff
Sharanjeet, Kaur
Signal change in BA17, 18 and 19: A comparative study of normal, glaucoma suspects and POAGpatients
description Magnetic resonance signal change is expected to be different between normal, glaucoma suspect (GS) and Primary Open Angle Glaucoma (POAG) subjects. Functional magnetic resonance imaging (fMRI) technique was employed to investigate the differences. This multiple subject studies were carried out to characterize the percentage of signal change (PSC) in Brodmann Area (BA) 17, 18 and 19 of the visual cortex. The block designed fMRI was implemented. The subjects were requested to focus on the black and white checkerboard stimulus of the visual world (A, B and CD), visual field (EF) and visual area (G). The data were analysed using Statistical Parametric Mapping (SPM8) via Matlab platform. results showed that GS subjects have the highest PSC, followed by normal and POAG subjects. However, no significant difference was observed in PSC between BA17, 18 and 19 for normal, GS and POAG groups with p = 0.0869, p = 0.0688 and p = 0.2690, respectively. In conclusion, none of the BA can be suggested to be the most dominant area in responding to the visual stimuli used in this study.
format Article
author Nurul Hanim, Nasaruddin
A N, Yusoff
Sharanjeet, Kaur
author_facet Nurul Hanim, Nasaruddin
A N, Yusoff
Sharanjeet, Kaur
author_sort Nurul Hanim, Nasaruddin
title Signal change in BA17, 18 and 19: A comparative study of normal, glaucoma suspects and POAGpatients
title_short Signal change in BA17, 18 and 19: A comparative study of normal, glaucoma suspects and POAGpatients
title_full Signal change in BA17, 18 and 19: A comparative study of normal, glaucoma suspects and POAGpatients
title_fullStr Signal change in BA17, 18 and 19: A comparative study of normal, glaucoma suspects and POAGpatients
title_full_unstemmed Signal change in BA17, 18 and 19: A comparative study of normal, glaucoma suspects and POAGpatients
title_sort signal change in ba17, 18 and 19: a comparative study of normal, glaucoma suspects and poagpatients
publisher IOP Publishing
publishDate 2020
url http://ir.unimas.my/id/eprint/32639/1/Nasaruddin.pdf
http://ir.unimas.my/id/eprint/32639/
https://iopscience.iop.org/article/10.1088/1742-6596/1497/1/012023
_version_ 1696979529509109760
score 13.211869

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