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One Pot and Two Pot Synthetic Strategies and Biological Applications of Epoxy‑Chalcones

Epoxy chalcone is a heterocyclic molecule and an important precursor for the synthesis of biologically active compounds. This mini-review is elucidating the synthetic strategies of chalcone epoxide via one pot and two pot routes including nature of reactants, nature of catalyst and variety of cataly...

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Main Authors: Zainab, Binti Ngaini, Saba, Farooq
Format: Article
Language:English
Published: The Tunisian Chemical Society and Springer Nature 2020
Subjects:
Q Science (General)
QD Chemistry
Online Access:http://ir.unimas.my/id/eprint/29701/1/saba.pdf
http://ir.unimas.my/id/eprint/29701/
https://link.springer.com/article/10.1007/s42250-020-00128-5
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spelling my.unimas.ir.297012021-03-30T04:12:25Z http://ir.unimas.my/id/eprint/29701/ One Pot and Two Pot Synthetic Strategies and Biological Applications of Epoxy‑Chalcones Zainab, Binti Ngaini Saba, Farooq Q Science (General) QD Chemistry Epoxy chalcone is a heterocyclic molecule and an important precursor for the synthesis of biologically active compounds. This mini-review is elucidating the synthetic strategies of chalcone epoxide via one pot and two pot routes including nature of reactants, nature of catalyst and variety of catalyst to improve yield of desired product, biological applications and advantages and drawbacks of these synthetic strategies. One pot route has wide variety of reactants and efcient one is the condensation of aldehyde and ketone. However, two pot route is consisted of chalcone synthesis preceding to epoxy chalcone. The synthetic routes for the preparation of epoxy chalcone and the usage as a precursor for the synthesis of various organic molecules with biological application is comprehensively discussed. This review is outstanding in organic chemistry and pharmaceutical industries to produce new molecules with various applications. The Tunisian Chemical Society and Springer Nature 2020 Article PeerReviewed text en http://ir.unimas.my/id/eprint/29701/1/saba.pdf Zainab, Binti Ngaini and Saba, Farooq (2020) One Pot and Two Pot Synthetic Strategies and Biological Applications of Epoxy‑Chalcones. Chemistry Africa. pp. 1-12. ISSN 522-5766 https://link.springer.com/article/10.1007/s42250-020-00128-5 DOI:org/10.1007/s42250-020-00128-5
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic Q Science (General)
QD Chemistry
spellingShingle Q Science (General)
QD Chemistry
Zainab, Binti Ngaini
Saba, Farooq
One Pot and Two Pot Synthetic Strategies and Biological Applications of Epoxy‑Chalcones
description Epoxy chalcone is a heterocyclic molecule and an important precursor for the synthesis of biologically active compounds. This mini-review is elucidating the synthetic strategies of chalcone epoxide via one pot and two pot routes including nature of reactants, nature of catalyst and variety of catalyst to improve yield of desired product, biological applications and advantages and drawbacks of these synthetic strategies. One pot route has wide variety of reactants and efcient one is the condensation of aldehyde and ketone. However, two pot route is consisted of chalcone synthesis preceding to epoxy chalcone. The synthetic routes for the preparation of epoxy chalcone and the usage as a precursor for the synthesis of various organic molecules with biological application is comprehensively discussed. This review is outstanding in organic chemistry and pharmaceutical industries to produce new molecules with various applications.
format Article
author Zainab, Binti Ngaini
Saba, Farooq
author_facet Zainab, Binti Ngaini
Saba, Farooq
author_sort Zainab, Binti Ngaini
title One Pot and Two Pot Synthetic Strategies and Biological Applications of Epoxy‑Chalcones
title_short One Pot and Two Pot Synthetic Strategies and Biological Applications of Epoxy‑Chalcones
title_full One Pot and Two Pot Synthetic Strategies and Biological Applications of Epoxy‑Chalcones
title_fullStr One Pot and Two Pot Synthetic Strategies and Biological Applications of Epoxy‑Chalcones
title_full_unstemmed One Pot and Two Pot Synthetic Strategies and Biological Applications of Epoxy‑Chalcones
title_sort one pot and two pot synthetic strategies and biological applications of epoxy‑chalcones
publisher The Tunisian Chemical Society and Springer Nature
publishDate 2020
url http://ir.unimas.my/id/eprint/29701/1/saba.pdf
http://ir.unimas.my/id/eprint/29701/
https://link.springer.com/article/10.1007/s42250-020-00128-5
_version_ 1696979509267398656
score 13.211869

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