Antimicrobial Properties of Sauropus androgynus against Crop and Human Pathogens
Synthetic fungicides and bactericides are widely used in today’s agricultural practices, though it is undeniably effective, it can leads to environmental pollution and consumers’ health problem and thus the needs to develop a more eco-friendly fungicide and bactericide based on organic sources such...
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| Main Author: | |
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| Format: | Final Year Project Report |
| Language: | English |
| Published: |
Universiti Malaysia Sarawak (UNIMAS)
2016
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| Online Access: | http://ir.unimas.my/id/eprint/24089/1/Empajang%20Anak%20Mandis%20ft.pdf http://ir.unimas.my/id/eprint/24089/ |
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| Summary: | Synthetic fungicides and bactericides are widely used in today’s agricultural practices, though it is undeniably effective, it can leads to environmental pollution and consumers’ health problem and thus the needs to develop a more eco-friendly fungicide and bactericide based on organic sources such as plant secondary metabolites. Previous studies have concluded that the plant Sauropus androgynus exhibit antimicrobial properties thus making it a potential candidate for making plant-based fungicide and bactericides as well as naturally derived medicines. Besides being able to eliminate the threat of agricultural practices, the development of medicine derived from plant metabolites also become a solution for the ever worsen problem of increasingly resistant human pathogens. The aim of this research is to study the
antimicrobial property of polar extract of S. androgynus leaves against three crop pathogenic fungi and four
human pathogenic bacteria. Two steps extraction method was used in order to obtain the polar extract, first
extraction using non-polar solvent (hexane) followed by polar solvent (80% methanol). Three concentrations
of the polar extract were used in the fungi growth inhibition test; four concentrations were used in the
bacteria growth inhibition test. From this experiment, it is concluded that the polar extract of S. androgynus
leaves showed no significant growth inhibitory activity against all the tested fungi (F. oxysporum, G.
cingulata and Colletotrichum sp.), instead it causes the growth rate of the fungi Colletotrichum sp. to be
significantly faster in comparison to control at 2% plant extract concentration. For the antibacterial test, the
polar extract of S. androgynus leaves showed no inhibitory activity toward the growth of all tested bacteria species (S. typhimurium, V. cholerea, L. monocytogenes and B. cereus). |
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