Acral melanoma of the extremities_a study of 33 cases Sarawakian patients
cral melanoma involve the non-pigmented palmoplantar and subungual areas and are commonly seen among Asians. Patients commonly display advanced stage of disease at presentation. It may appear unnoticed and mimic benign lesions. Methods: Data for this retrospective study was retrieved from Histopatho...
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Medical Journal of Malaysia
2012
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my.unimas.ir.22092015-03-19T01:49:05Z http://ir.unimas.my/id/eprint/2209/ Acral melanoma of the extremities_a study of 33 cases Sarawakian patients Zainal, A.I Zulkarnaen, M. Norlida, D.K Syed Alwi, S.A.R Q Science (General) R Medicine (General) cral melanoma involve the non-pigmented palmoplantar and subungual areas and are commonly seen among Asians. Patients commonly display advanced stage of disease at presentation. It may appear unnoticed and mimic benign lesions. Methods: Data for this retrospective study was retrieved from Histopathology Unit, Sarawak General Hospital, Malaysia archive from 2003 to 2009. Result: 62.3% cases of malignant melanoma were acral melanoma. The mean age of diagnosis was 64.3±12.1. The involved sites were the heel (39.4%), middle and frontal plantar area (24.2%), toe (24.2%) and web spaces (9.1%). The clinical presentations were; an enlarging mass (60.6%), nonhealing ulcer (24.2%) and abnormal pigmented lesion (15.2%). Most cases exhibited Breslow thickness >4.00 mm (87.9%) and Clark’s levels V (50%). The majority showed moderate (non brisk) tumour infiltrating lymphocytes (57.6%). Ulceration (84.8%) and lymphovascular involvement were seen (24.2%). Conclusion: Acral melanoma is the commonest malignant melanoma in this Sarawakian cohort. Most of the cases presented with advanced stage disease. Medical Journal of Malaysia 2012 E-Article NonPeerReviewed text en http://ir.unimas.my/id/eprint/2209/1/Acral%20melanoma%20of%20the%20extremities_a%20study%20of%2033%20cases%20Sarawakian%20patients.pdf Zainal, A.I and Zulkarnaen, M. and Norlida, D.K and Syed Alwi, S.A.R (2012) Acral melanoma of the extremities_a study of 33 cases Sarawakian patients. Medical Journal of Malaysia, 67 (1). |
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Q Science (General) R Medicine (General) Zainal, A.I Zulkarnaen, M. Norlida, D.K Syed Alwi, S.A.R Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| description |
cral melanoma involve the non-pigmented palmoplantar and subungual areas and are commonly seen among Asians. Patients commonly display advanced stage of disease at presentation. It may appear unnoticed and mimic benign lesions. Methods: Data for this retrospective study was retrieved from Histopathology Unit, Sarawak General Hospital, Malaysia archive from 2003 to 2009. Result: 62.3% cases of malignant melanoma were acral melanoma. The mean age of diagnosis was 64.3±12.1. The involved sites were the heel (39.4%), middle and frontal plantar area (24.2%), toe (24.2%) and web spaces (9.1%). The clinical presentations were; an enlarging mass (60.6%), nonhealing ulcer (24.2%) and abnormal pigmented lesion (15.2%). Most cases exhibited Breslow thickness >4.00 mm (87.9%) and Clark’s levels V (50%). The majority showed moderate (non brisk) tumour infiltrating lymphocytes (57.6%). Ulceration (84.8%) and lymphovascular involvement were seen (24.2%). Conclusion: Acral melanoma is the commonest malignant melanoma in this Sarawakian cohort. Most of the cases presented with advanced stage disease. |
| format |
E-Article |
| author |
Zainal, A.I Zulkarnaen, M. Norlida, D.K Syed Alwi, S.A.R |
| author_facet |
Zainal, A.I Zulkarnaen, M. Norlida, D.K Syed Alwi, S.A.R |
| author_sort |
Zainal, A.I |
| title |
Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_short |
Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_full |
Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_fullStr |
Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_full_unstemmed |
Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_sort |
acral melanoma of the extremities_a study of 33 cases sarawakian patients |
| publisher |
Medical Journal of Malaysia |
| publishDate |
2012 |
| url |
http://ir.unimas.my/id/eprint/2209/1/Acral%20melanoma%20of%20the%20extremities_a%20study%20of%2033%20cases%20Sarawakian%20patients.pdf http://ir.unimas.my/id/eprint/2209/ |
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1644509043118571520 |
| score |
13.211869 |