Chemical studies on the essential oils of several cinnamomum species and their biological activitie
The essential oils isolated from leaves, root, root-bark and stem-bark of foul' Cinnamonwl/1 spp. (Cinnamomum sp. 1, C fahUanulJ1, C gr!ffithii and C. javan icum) using hydrodisrillation method were analyzed by gas chromatography-mass spectrometry (GC-MS) and their chemical constituents were co...
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| Format: | Final Year Project Report |
| Language: | English |
| Published: |
Universiti Malaysia Sarawak (UNIMAS)
2007
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| Online Access: | http://ir.unimas.my/id/eprint/20005/8/Chemical%20studies%20on%20the%20essential%20oils%20%28fulltext%29.pdf http://ir.unimas.my/id/eprint/20005/ |
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| Summary: | The essential oils isolated from leaves, root, root-bark and stem-bark of foul' Cinnamonwl/1 spp. (Cinnamomum sp. 1, C fahUanulJ1, C gr!ffithii and C. javan icum) using hydrodisrillation method were analyzed by gas chromatography-mass spectrometry (GC-MS) and their chemical constituents were compared. Kovat indices for individual component in the essential oils were determined and these indices were used for identification. The percentage yield of the essential oi ls ranged between 0.26-9.56(Yo and stem-bark of Cil1l7am0ll1 l1111 sp. 1 gave the highest yield percentage of essential oi l. The major components in the essential oils of Cil7l1amomu m sp. 1 were 8cadinol
(11.78%), dielhyl malonale (7.89%), 2-oclonal (7.16%), isoborneol (6.94%), hydrocinnamic acid (42.70%), (£)-a-bergamolene (44.27%), isocaryophyllene (8.74%), cinnamyl alcohol (8.70%), (£)-isoelemicin (7.47%), (-)-yelemene
(64.81 %) and p-bisabolol (10.86%). Meanwhile, the major components of the C. lahijanuln essential oils were p-phellandrene (9.23%), u-cad inol (6.52%), (-)-y-elemene (24.53%). p-selinene (16.71%), wine laclone (19.60%), p-farnesene (12.71%), (£)-a-bergamolene (11.12%), geranyl isovalerale (14.73%), y-dodecalaclone (14.07%), cedrenol (18.95%) and p-eudesmol (6.28%). C. griffithii essential oils contain nilro-phenylethane
(7. 16%), 1,3-p-menlhadiene-7-01 (6.57%), a-copaene (7.3 1%), (-)-y-elemene (8.82%), eudesmol (7.75%), (2)-3hexenyl-
2-melhylbutanoate (7.58%), nonanoic acid (24.69%), ~-bourbonene (17.94%) and ethyl benzoale (14.72%) as the major components. The major components in the essential oils of C. javQniclIm were perilla aldehyde (47.23%), (£)-~-damascone (25.18%), decadienal (26.57%), (-)-y-elemenc (24.76%), hydrocinnamic acid (16.24%), (£)-u-bergamolene (12.14%), di ll apiol (1 1.97%), melhyl cinnamate (11 .8 1%), styrene glycol (8.23%) and 10-epi-yeudesmol
(7.45%). C. javanicum young and matured leaves essential oils contain similar major compounds with similar amounl which were peri lla aldehyde (47.23% and 36.61%) and (£)-~-damascone (25.18% and 24.62%). The toxicity of each essential oil from the fo ur CinnamolJ1um spp. was investigated using brine shrimp, Anemia salina. Results from the brine shrimp lethality test showed that the essential oils of CinnQmomum sp. 1 stem-bark, C. lallijanum root, C. gnffithi; root-bark and Cjavanicum root-bark possessed the st rongest lethality activities against Artemia salina with the lethal concentration (LC 50) value of 50 fJglmL. |
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