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Comparison of RPL14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium

Nasopharyngeal carcinoma (NPC) is predominant cancer in Southern China and Southeast Asia which affect Cantonese inheritance. Previous research showed that ribosomal preteins (RPs) gene expression in nasopharyngeal carcinoma (NPC) are differ frim normal human nasopharyngeal epithelium cells with mo...

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Bibliographic Details
Main Author: Nur Atiqah, Azman
Format: Final Year Project Report
Language:English
English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2016
Subjects:
RB Pathology
Online Access:http://ir.unimas.my/id/eprint/15355/1/Nur%20Atiqah.pdf
http://ir.unimas.my/id/eprint/15355/4/Nur%20Atiqah%20full.pdf
http://ir.unimas.my/id/eprint/15355/
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spelling my.unimas.ir.153552024-02-09T03:17:47Z http://ir.unimas.my/id/eprint/15355/ Comparison of RPL14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium Nur Atiqah, Azman RB Pathology Nasopharyngeal carcinoma (NPC) is predominant cancer in Southern China and Southeast Asia which affect Cantonese inheritance. Previous research showed that ribosomal preteins (RPs) gene expression in nasopharyngeal carcinoma (NPC) are differ frim normal human nasopharyngeal epithelium cells with most RPs that are being down-regulated. Recent studies showed that disturbance of RPs might induce tumorigenesis. However, there is a lack of study done regarding RPL14 specific investigation on NPC. Therefore, this study is proposed to extract Ribosomal Protein L14 gene (RPL14) to compare the differences on expression level in human nasopharyngeal cell lines (normal and carcinoma) by using a standard protocol, RNA was extracted by Trizol as starting material in this project and amplified using Reverse Transcription-Polymerase Chain Reaction (RT-PCR) with the aid of software Image Quant TL. This study revealed the PCR product wiht a length of 760 bp in RPL14. There is significant difference of RPL14 expression levels in NPC. Universiti Malaysia Sarawak, (UNIMAS) 2016 Final Year Project Report NonPeerReviewed text en http://ir.unimas.my/id/eprint/15355/1/Nur%20Atiqah.pdf text en http://ir.unimas.my/id/eprint/15355/4/Nur%20Atiqah%20full.pdf Nur Atiqah, Azman (2016) Comparison of RPL14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium. [Final Year Project Report] (Unpublished)
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
English
topic RB Pathology
spellingShingle RB Pathology
Nur Atiqah, Azman
Comparison of RPL14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium
description Nasopharyngeal carcinoma (NPC) is predominant cancer in Southern China and Southeast Asia which affect Cantonese inheritance. Previous research showed that ribosomal preteins (RPs) gene expression in nasopharyngeal carcinoma (NPC) are differ frim normal human nasopharyngeal epithelium cells with most RPs that are being down-regulated. Recent studies showed that disturbance of RPs might induce tumorigenesis. However, there is a lack of study done regarding RPL14 specific investigation on NPC. Therefore, this study is proposed to extract Ribosomal Protein L14 gene (RPL14) to compare the differences on expression level in human nasopharyngeal cell lines (normal and carcinoma) by using a standard protocol, RNA was extracted by Trizol as starting material in this project and amplified using Reverse Transcription-Polymerase Chain Reaction (RT-PCR) with the aid of software Image Quant TL. This study revealed the PCR product wiht a length of 760 bp in RPL14. There is significant difference of RPL14 expression levels in NPC.
format Final Year Project Report
author Nur Atiqah, Azman
author_facet Nur Atiqah, Azman
author_sort Nur Atiqah, Azman
title Comparison of RPL14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium
title_short Comparison of RPL14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium
title_full Comparison of RPL14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium
title_fullStr Comparison of RPL14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium
title_full_unstemmed Comparison of RPL14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium
title_sort comparison of rpl14 expression levels between normal and tumour cells of juma nasopharyngeal epithelium
publisher Universiti Malaysia Sarawak, (UNIMAS)
publishDate 2016
url http://ir.unimas.my/id/eprint/15355/1/Nur%20Atiqah.pdf
http://ir.unimas.my/id/eprint/15355/4/Nur%20Atiqah%20full.pdf
http://ir.unimas.my/id/eprint/15355/
_version_ 1792160590423130112
score 13.211869

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