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Blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump

This paper presents a titanium quadrupletip micro-needle integrated with a micropump with different inner designs, length and diameter of the micro-channels to measure and maximize the velocity flow in the micro-needle as blood delivered into human body. Titanium is used as the material of the mi...

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Main Authors: MD, Ibrahim, YS, Yunos, ARH, Rigit, NAA, Mohtadzar, N, Watanabe, Y, Sunami, MRA, Rahman, LK, Wong, MZ, Mohtar
Format: E-Article
Language:English
Published: IOP Publishing Ltd. 2017
Subjects:
TJ Mechanical engineering and machinery
Online Access:http://ir.unimas.my/id/eprint/14863/1/Blood-mimicking%20delivery%20in%20polygonal%20structure%20of%20inner%20quadrupletip%20microneedle%20with%20valveless%20micro-pump%20%28abstract%29.pdf
http://ir.unimas.my/id/eprint/14863/
http://iopscience.iop.org/article/10.1088/1742-6596/822/1/012025/meta
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spelling my.unimas.ir.148632018-01-03T06:19:14Z http://ir.unimas.my/id/eprint/14863/ Blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump MD, Ibrahim YS, Yunos ARH, Rigit NAA, Mohtadzar N, Watanabe Y, Sunami MRA, Rahman LK, Wong MZ, Mohtar TJ Mechanical engineering and machinery This paper presents a titanium quadrupletip micro-needle integrated with a micropump with different inner designs, length and diameter of the micro-channels to measure and maximize the velocity flow in the micro-needle as blood delivered into human body. Titanium is used as the material of the micro-needle which are also the common material in manufacturing of micro-needle. The advancement of micro-needle technologies is improved in penetrating human outermost skin, stratum corneum and further to human blood vessels. The micro-needles with channel inner design of circular, square, hexagon, and dodecagon with quadruple tip designs are drawn with inner diameter parameter of 150μm and 100μm with two different channel length which are 10mm and 25mm. The characteristics of blood delivery in geometrically changed inner designs affect the output velocity in microneedle when the micropump is operating. The results showed that, when it is pumped at 0.04m/s, the blood velocity improved by 5.6% than when the pump is increased by 30% of its capacity. This is due to the backflow generated in the micropump. IOP Publishing Ltd. 2017 E-Article PeerReviewed text en http://ir.unimas.my/id/eprint/14863/1/Blood-mimicking%20delivery%20in%20polygonal%20structure%20of%20inner%20quadrupletip%20microneedle%20with%20valveless%20micro-pump%20%28abstract%29.pdf MD, Ibrahim and YS, Yunos and ARH, Rigit and NAA, Mohtadzar and N, Watanabe and Y, Sunami and MRA, Rahman and LK, Wong and MZ, Mohtar (2017) Blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump. Journal of Physics: Conference Series, 822 (1). ISSN ‎1742-6588 (print) http://iopscience.iop.org/article/10.1088/1742-6596/822/1/012025/meta DOI: 10.1088/1742-6596/822/1/012025
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic TJ Mechanical engineering and machinery
spellingShingle TJ Mechanical engineering and machinery
MD, Ibrahim
YS, Yunos
ARH, Rigit
NAA, Mohtadzar
N, Watanabe
Y, Sunami
MRA, Rahman
LK, Wong
MZ, Mohtar
Blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump
description This paper presents a titanium quadrupletip micro-needle integrated with a micropump with different inner designs, length and diameter of the micro-channels to measure and maximize the velocity flow in the micro-needle as blood delivered into human body. Titanium is used as the material of the micro-needle which are also the common material in manufacturing of micro-needle. The advancement of micro-needle technologies is improved in penetrating human outermost skin, stratum corneum and further to human blood vessels. The micro-needles with channel inner design of circular, square, hexagon, and dodecagon with quadruple tip designs are drawn with inner diameter parameter of 150μm and 100μm with two different channel length which are 10mm and 25mm. The characteristics of blood delivery in geometrically changed inner designs affect the output velocity in microneedle when the micropump is operating. The results showed that, when it is pumped at 0.04m/s, the blood velocity improved by 5.6% than when the pump is increased by 30% of its capacity. This is due to the backflow generated in the micropump.
format E-Article
author MD, Ibrahim
YS, Yunos
ARH, Rigit
NAA, Mohtadzar
N, Watanabe
Y, Sunami
MRA, Rahman
LK, Wong
MZ, Mohtar
author_facet MD, Ibrahim
YS, Yunos
ARH, Rigit
NAA, Mohtadzar
N, Watanabe
Y, Sunami
MRA, Rahman
LK, Wong
MZ, Mohtar
author_sort MD, Ibrahim
title Blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump
title_short Blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump
title_full Blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump
title_fullStr Blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump
title_full_unstemmed Blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump
title_sort blood-mimicking delivery in polygonal structure of inner quadrupletip microneedle with valveless micro-pump
publisher IOP Publishing Ltd.
publishDate 2017
url http://ir.unimas.my/id/eprint/14863/1/Blood-mimicking%20delivery%20in%20polygonal%20structure%20of%20inner%20quadrupletip%20microneedle%20with%20valveless%20micro-pump%20%28abstract%29.pdf
http://ir.unimas.my/id/eprint/14863/
http://iopscience.iop.org/article/10.1088/1742-6596/822/1/012025/meta
_version_ 1644512016477454336
score 13.211869

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