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Echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication

Introduction The novel subgroup of Heart Failure with improved ejection fraction(HFimpEF) is focused on improving left ventricle systolic function, but there is sparse data on left atrial(LA) recovery. Recent studies observed reversal remodelling of LA echocardiographic volume indices in HFimpEF. H...

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Main Authors: Hwei Sung, Ling, en ze, Chan, Han Bing, Chow
Format: Article
Language:English
Published: Elsevier 2023
Subjects:
R Medicine (General)
Online Access:http://ir.unimas.my/id/eprint/47082/1/Echocardiographic%20improvement%20of%20left%20atrial%20booster%20pump%20and%20reservoir%20function%20observed%20in%20heart%20failure%20with%20improved%20ejection%20fraction%20and%20its%20prognostication.pdf
http://ir.unimas.my/id/eprint/47082/
https://www.sciencedirect.com/science/article/abs/pii/S0167527323015206
https://doi.org/10.1016/j.ijcard.2023.131458
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spelling my.unimas.ir-470822024-12-31T04:00:50Z http://ir.unimas.my/id/eprint/47082/ Echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication Hwei Sung, Ling en ze, Chan Han Bing, Chow R Medicine (General) Introduction The novel subgroup of Heart Failure with improved ejection fraction(HFimpEF) is focused on improving left ventricle systolic function, but there is sparse data on left atrial(LA) recovery. Recent studies observed reversal remodelling of LA echocardiographic volume indices in HFimpEF. However, there is a lack of data on the echocardiographic description of volumetric LA functions, such as booster pump and reservoir dysfunction, in patients with HFimpEF. Objectives 1To describe the changes in echocardiographic volumetric indexes of LA function, such as changes in LA reservoir function, LA conduit function, LA booster pump and LA sphericity index in a patient with HFimpEF. 2To examine the correlation of these volumetric indexes with NT-ProBNP, 1-year composite mortality or heart failure (HF) events outcome. Method This observational study in Sarawak Heart Center, HF clinic, involves 53 consecutive patients with HFimpEF. Clinical records, echocardiographic data and 1-year composite clinical outcomes were analyzed retrospectively. Results The mean age is 52 ± 14 years; 81% were male, and 73% were non-ischemic in aetiology. All 53 were NYHA class I/II. 75.5% had hypertension, and 45.3% had diabetes. 17% had atrial fibrillation(AF). The median index left ventricle ejection fraction (LVEF), and NT-ProBNP were 54.4(44.1-61.1)% and 109.7(34.5-444.1)pg/ml. The median LA Volume indexed by body surface area(LAVI) of the initial echocardiography was 33.9(26.2-45.6) mL/m2, of which 49.1% were enlarged (LAVI >34 ml/m2), while the median Conclusion In our study cohort, HFimpEF is followed by favourable LA reverse remodelling. More study is needed to explore the prognostic significance of this finding among HFimpEF patients. Elsevier 2023-12 Article PeerReviewed text en http://ir.unimas.my/id/eprint/47082/1/Echocardiographic%20improvement%20of%20left%20atrial%20booster%20pump%20and%20reservoir%20function%20observed%20in%20heart%20failure%20with%20improved%20ejection%20fraction%20and%20its%20prognostication.pdf Hwei Sung, Ling and en ze, Chan and Han Bing, Chow (2023) Echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication. International Journal of Cardiology, 393 (131458). ISSN 1874-1754 https://www.sciencedirect.com/science/article/abs/pii/S0167527323015206 https://doi.org/10.1016/j.ijcard.2023.131458
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Hwei Sung, Ling
en ze, Chan
Han Bing, Chow
Echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication
description Introduction The novel subgroup of Heart Failure with improved ejection fraction(HFimpEF) is focused on improving left ventricle systolic function, but there is sparse data on left atrial(LA) recovery. Recent studies observed reversal remodelling of LA echocardiographic volume indices in HFimpEF. However, there is a lack of data on the echocardiographic description of volumetric LA functions, such as booster pump and reservoir dysfunction, in patients with HFimpEF. Objectives 1To describe the changes in echocardiographic volumetric indexes of LA function, such as changes in LA reservoir function, LA conduit function, LA booster pump and LA sphericity index in a patient with HFimpEF. 2To examine the correlation of these volumetric indexes with NT-ProBNP, 1-year composite mortality or heart failure (HF) events outcome. Method This observational study in Sarawak Heart Center, HF clinic, involves 53 consecutive patients with HFimpEF. Clinical records, echocardiographic data and 1-year composite clinical outcomes were analyzed retrospectively. Results The mean age is 52 ± 14 years; 81% were male, and 73% were non-ischemic in aetiology. All 53 were NYHA class I/II. 75.5% had hypertension, and 45.3% had diabetes. 17% had atrial fibrillation(AF). The median index left ventricle ejection fraction (LVEF), and NT-ProBNP were 54.4(44.1-61.1)% and 109.7(34.5-444.1)pg/ml. The median LA Volume indexed by body surface area(LAVI) of the initial echocardiography was 33.9(26.2-45.6) mL/m2, of which 49.1% were enlarged (LAVI >34 ml/m2), while the median Conclusion In our study cohort, HFimpEF is followed by favourable LA reverse remodelling. More study is needed to explore the prognostic significance of this finding among HFimpEF patients.
format Article
author Hwei Sung, Ling
en ze, Chan
Han Bing, Chow
author_facet Hwei Sung, Ling
en ze, Chan
Han Bing, Chow
author_sort Hwei Sung, Ling
title Echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication
title_short Echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication
title_full Echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication
title_fullStr Echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication
title_full_unstemmed Echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication
title_sort echocardiographic improvement of left atrial booster pump and reservoir function observed in heart failure with improved ejection fraction and its prognostication
publisher Elsevier
publishDate 2023
url http://ir.unimas.my/id/eprint/47082/1/Echocardiographic%20improvement%20of%20left%20atrial%20booster%20pump%20and%20reservoir%20function%20observed%20in%20heart%20failure%20with%20improved%20ejection%20fraction%20and%20its%20prognostication.pdf
http://ir.unimas.my/id/eprint/47082/
https://www.sciencedirect.com/science/article/abs/pii/S0167527323015206
https://doi.org/10.1016/j.ijcard.2023.131458
_version_ 1821007910124126208
score 13.235796

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