Type 1 or type 2 diabetes : has the ship already sailed?
Introduction Type 1 diabetes is an autoimmune condition characterised by loss of pancreatic beta cells and therefore insulin production. C-peptide, secreted in equal amounts to insulin, can be used to assess beta cell function, the concentration being reflective of endogenous insulin production.1...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Association of British Clinical Diabetologists
2021
|
| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/46838/1/Type%201%20or%20type%202%20diabetes.pdf http://ir.unimas.my/id/eprint/46838/ https://www.bjd-abcd.com/index.php/bjd/article/view/705 https://doi.org/10.15277/bjd.2021.297 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Introduction
Type 1 diabetes is an autoimmune condition characterised by loss of pancreatic beta cells and therefore insulin production. C-peptide, secreted in equal amounts to insulin, can be used to assess beta cell function, the concentration being reflective of endogenous insulin production.1
Type 1 diabetes is often associated with other organ-specific autoimmune conditions, most commonly autoimmune thyroid disease, associated with thyroid peroxidase antibodies, and coeliac disease, associated with tissue transglutaminase antibodies.2 Islet autoantibodies to islet tyrosine phosphatase antigen-2 (IA-2), glutamate decarboxylase (GAD-65) and zinc transporter 8 (ZnT8) can
be seen in patients who develop type 1 diabetes months to years prior to diagnosis.3 One of more of these antibodies is present in 80–90% of patients with type 1 diabetes at the time of diagnosis. |
|---|