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Type 2 diabetes presenting with DKA and severe hypertriglyceridaemia

Endolymphatic sac tumour (ELST) is a non‑metastasizing low grade adenocarcinoma of endolymphatic sac origin. It is also known as Heffner tumour, low grade adenocarcinoma of endolymphatic sac origin and aggressive papillary middle ear tumour. These tumours are closely associated with Von Hippel Lind...

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Main Authors: Sim, Sing Yee, Marie-France, Kong, Faizanur, Rahman
Format: Article
Language:English
Published: Association of British Clinical Diabetologists 2018
Subjects:
R Medicine (General)
Online Access:http://ir.unimas.my/id/eprint/46816/1/Type%202%20diabetes%20presenting.pdf
http://ir.unimas.my/id/eprint/46816/
https://bjd-abcd.com/index.php/bjd/article/view/367
https://doi.org/10.15277/bjd.2018.183
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spelling my.unimas.ir-468162024-12-09T02:53:03Z http://ir.unimas.my/id/eprint/46816/ Type 2 diabetes presenting with DKA and severe hypertriglyceridaemia Sim, Sing Yee Marie-France, Kong Faizanur, Rahman R Medicine (General) Endolymphatic sac tumour (ELST) is a non‑metastasizing low grade adenocarcinoma of endolymphatic sac origin. It is also known as Heffner tumour, low grade adenocarcinoma of endolymphatic sac origin and aggressive papillary middle ear tumour. These tumours are closely associated with Von Hippel Lindau (VHL) disease. Here we report a case of Endolymphatic sac tumour in a 63 yr old lady who presented with left sided facial palsy. Since the tumour was highly vascular and required preoperative embolization, initial clinicoradiological diagnosis was Jugulotymphanic paraganglioma. Histopathology showed features of Endolymphatic sac tumour, which was confirmed by immunohistochemistry. Since this tumour is locally aggressive low grade adenocarcinoma, the diagnosis is difficult in advanced cases where there is erosion of petrous temporal bone or the lesion shows extension into cerebellopontine angle as in our case. Since the association of this tumour with VHL disease is well established, it is important to screen all the patients of VHL disease for this lesion and also all the patients of ELST should be screened for other lesions of VHL disease to aid in early diagnosis and treatment. The case is presented here for its rarity and difficulty in initial diagnosis. Association of British Clinical Diabetologists 2018 Article PeerReviewed text en http://ir.unimas.my/id/eprint/46816/1/Type%202%20diabetes%20presenting.pdf Sim, Sing Yee and Marie-France, Kong and Faizanur, Rahman (2018) Type 2 diabetes presenting with DKA and severe hypertriglyceridaemia. The British Journal of Diabetes (BJD), 18 (3). pp. 113-116. ISSN 2397-6241 https://bjd-abcd.com/index.php/bjd/article/view/367 https://doi.org/10.15277/bjd.2018.183
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Sim, Sing Yee
Marie-France, Kong
Faizanur, Rahman
Type 2 diabetes presenting with DKA and severe hypertriglyceridaemia
description Endolymphatic sac tumour (ELST) is a non‑metastasizing low grade adenocarcinoma of endolymphatic sac origin. It is also known as Heffner tumour, low grade adenocarcinoma of endolymphatic sac origin and aggressive papillary middle ear tumour. These tumours are closely associated with Von Hippel Lindau (VHL) disease. Here we report a case of Endolymphatic sac tumour in a 63 yr old lady who presented with left sided facial palsy. Since the tumour was highly vascular and required preoperative embolization, initial clinicoradiological diagnosis was Jugulotymphanic paraganglioma. Histopathology showed features of Endolymphatic sac tumour, which was confirmed by immunohistochemistry. Since this tumour is locally aggressive low grade adenocarcinoma, the diagnosis is difficult in advanced cases where there is erosion of petrous temporal bone or the lesion shows extension into cerebellopontine angle as in our case. Since the association of this tumour with VHL disease is well established, it is important to screen all the patients of VHL disease for this lesion and also all the patients of ELST should be screened for other lesions of VHL disease to aid in early diagnosis and treatment. The case is presented here for its rarity and difficulty in initial diagnosis.
format Article
author Sim, Sing Yee
Marie-France, Kong
Faizanur, Rahman
author_facet Sim, Sing Yee
Marie-France, Kong
Faizanur, Rahman
author_sort Sim, Sing Yee
title Type 2 diabetes presenting with DKA and severe hypertriglyceridaemia
title_short Type 2 diabetes presenting with DKA and severe hypertriglyceridaemia
title_full Type 2 diabetes presenting with DKA and severe hypertriglyceridaemia
title_fullStr Type 2 diabetes presenting with DKA and severe hypertriglyceridaemia
title_full_unstemmed Type 2 diabetes presenting with DKA and severe hypertriglyceridaemia
title_sort type 2 diabetes presenting with dka and severe hypertriglyceridaemia
publisher Association of British Clinical Diabetologists
publishDate 2018
url http://ir.unimas.my/id/eprint/46816/1/Type%202%20diabetes%20presenting.pdf
http://ir.unimas.my/id/eprint/46816/
https://bjd-abcd.com/index.php/bjd/article/view/367
https://doi.org/10.15277/bjd.2018.183
_version_ 1818839385606455296
score 13.223943

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