Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement
Malaysian Technical Universities Conference on Engineering and Technology (MUCEET) 2009 organized by Universiti Malaysia Pahang in collaboration with Universiti Tun Hussein Onn Malaysia, Universiti Teknikal Malaysia Melaka & Universiti Malaysia Perlis, 20th - 22nd June 2009 at MS Garden Hotel, K...
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Universiti Malaysia Pahang
2010
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my.unimap-85112010-08-06T10:01:45Z Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement A., Mat Taib Uda, Hashim, Prof. Dr. N. A., Yusof Th. S., Dhahi Nanogap sensing Dielectric biosensor Label-free detection Silicon nanostructure Bio-molecule immobilization Hybridization MUCEET 2009 Malaysian Technical Universities Conference on Engineering and Technology 2009 Malaysian Technical Universities Conference on Engineering and Technology (MUCEET) 2009 organized by Universiti Malaysia Pahang in collaboration with Universiti Tun Hussein Onn Malaysia, Universiti Teknikal Malaysia Melaka & Universiti Malaysia Perlis, 20th - 22nd June 2009 at MS Garden Hotel, Kuantan, Pahang, Malaysia. Biosensor with electrode distances 75 nm and highly sensitive and selective is proposed in this research. The target application is the label-free detection of bio-molecular interaction for medical diagnostic analytical measurement. The fabrication process of the biosensor is based on conventional photolithography, e-beam evaporation and wet etching process. Sacrificial layer technique is applied in this research to form nanometer gap size between bottom and top electrode. Gold was chosen because of its properties that inert to atmosphere conditions and resistance to saline solution for bio-molecules immobilization and hybridization. For morphological and physical characterization, SEM, TEM and AFM are will be used while for electrical characterization, SPA and IV-CV system is used to determine the conductivity, capacitance and resistivity of the device. DNA is used as a sample for testing and the DNA extraction and preparation is done prior to immobilization and hybridization. 2010-08-06T10:01:45Z 2010-08-06T10:01:45Z 2009-06-20 Working Paper p.1-5 http://hdl.handle.net/123456789/8511 en Proceedings of the Malaysian Technical Universities Conference on Engineering and Technology (MUCEET) 2009 Universiti Malaysia Pahang |
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Nanogap sensing Dielectric biosensor Label-free detection Silicon nanostructure Bio-molecule immobilization Hybridization MUCEET 2009 Malaysian Technical Universities Conference on Engineering and Technology 2009 |
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Nanogap sensing Dielectric biosensor Label-free detection Silicon nanostructure Bio-molecule immobilization Hybridization MUCEET 2009 Malaysian Technical Universities Conference on Engineering and Technology 2009 A., Mat Taib Uda, Hashim, Prof. Dr. N. A., Yusof Th. S., Dhahi Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement |
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Malaysian Technical Universities Conference on Engineering and Technology (MUCEET) 2009 organized by Universiti Malaysia Pahang in collaboration with Universiti Tun Hussein Onn Malaysia, Universiti Teknikal Malaysia Melaka & Universiti Malaysia Perlis, 20th - 22nd June 2009 at MS Garden Hotel, Kuantan, Pahang, Malaysia. |
format |
Working Paper |
author |
A., Mat Taib Uda, Hashim, Prof. Dr. N. A., Yusof Th. S., Dhahi |
author_facet |
A., Mat Taib Uda, Hashim, Prof. Dr. N. A., Yusof Th. S., Dhahi |
author_sort |
A., Mat Taib |
title |
Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement |
title_short |
Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement |
title_full |
Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement |
title_fullStr |
Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement |
title_full_unstemmed |
Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement |
title_sort |
development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement |
publisher |
Universiti Malaysia Pahang |
publishDate |
2010 |
url |
http://dspace.unimap.edu.my/xmlui/handle/123456789/8511 |
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1643789198987100160 |
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13.222552 |