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Development of nanogap automated permittivity measurement system for DNA hybridization detection kit

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Main Authors:	Saifullah, A., Azri, M. E., Uda, Hashim, Prof. Dr.
Format:	Working Paper
Language:	English
Published:	Institute of Electrical and Electronics Engineering (IEEE) 2010
Subjects:	Automated measurement systems Current waves DNA sensors Double-stranded DNA (ds-DNA) Nano-gap Permittivity values Single-stranded DNA (ss-DNA)
Online Access:	http://dspace.unimap.edu.my/xmlui/handle/123456789/8447
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spelling	my.unimap-84472013-11-20T03:53:31Z Development of nanogap automated permittivity measurement system for DNA hybridization detection kit Saifullah, A. Azri, M. E. Uda, Hashim, Prof. Dr. Automated measurement systems Current waves DNA sensors Double-stranded DNA (ds-DNA) Nano-gap Permittivity values Single-stranded DNA (ss-DNA) Link to publisher's homepage at http://ieeexplore.ieee.org/ The Nanogap Automated Permittivity Measurement System (APMS) are fabricated as low cost, portable and label free DNA hybridization detection kit. The nanogap capacitor can react as a dna sensor. The difference in dielectric properties of singlestranded DNA (SSDNA) and double-stranded DNA (DSDNA) are allowing the use of permittivity measurement for DNA hybridization detection. In this project, an automated measurement system is introduced as an interface for nanogap capacitor. Sine wave frequency from 1Hz until 100kHz will be applied to the nanogap capacitor and it voltage wave and current wave are measured and analyzed. Three measurements will be made, capacitance measurement of nanogap with no sample, permittivity measurement of after immobilization and after hybridization. If the measurement show a considerably difference in permittivity value, the DNA is consider hybridize. Otherwise is it considered mismatch. In this project, an Artificial Neural Network (ANN) will also be introduced for decision making of the result based on the permittivity measurement. This will allow the user to get the result without comparing the output. 2010-08-03T08:54:58Z 2010-08-03T08:54:58Z 2009-12-14 Working Paper p.1-4 978-142445223-1 http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=5412092&tag=1 http://hdl.handle.net/123456789/8447 en Proceedings of the International Conference for Technical Postgraduates (TECHPOS) 2009 Institute of Electrical and Electronics Engineering (IEEE)
institution	Universiti Malaysia Perlis
building	UniMAP Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Perlis
content_source	UniMAP Library Digital Repository
url_provider	http://dspace.unimap.edu.my/
language	English
topic	Automated measurement systems Current waves DNA sensors Double-stranded DNA (ds-DNA) Nano-gap Permittivity values Single-stranded DNA (ss-DNA)
spellingShingle	Automated measurement systems Current waves DNA sensors Double-stranded DNA (ds-DNA) Nano-gap Permittivity values Single-stranded DNA (ss-DNA) Saifullah, A. Azri, M. E. Uda, Hashim, Prof. Dr. Development of nanogap automated permittivity measurement system for DNA hybridization detection kit
description	Link to publisher's homepage at http://ieeexplore.ieee.org/
format	Working Paper
author	Saifullah, A. Azri, M. E. Uda, Hashim, Prof. Dr.
author_facet	Saifullah, A. Azri, M. E. Uda, Hashim, Prof. Dr.
author_sort	Saifullah, A.
title	Development of nanogap automated permittivity measurement system for DNA hybridization detection kit
title_short	Development of nanogap automated permittivity measurement system for DNA hybridization detection kit
title_full	Development of nanogap automated permittivity measurement system for DNA hybridization detection kit
title_fullStr	Development of nanogap automated permittivity measurement system for DNA hybridization detection kit
title_full_unstemmed	Development of nanogap automated permittivity measurement system for DNA hybridization detection kit
title_sort	development of nanogap automated permittivity measurement system for dna hybridization detection kit
publisher	Institute of Electrical and Electronics Engineering (IEEE)
publishDate	2010
url	http://dspace.unimap.edu.my/xmlui/handle/123456789/8447
_version_	1643789187037528064
score	13.222552

Development of nanogap automated permittivity measurement system for DNA hybridization detection kit

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