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Fabrication and characterization of tissue engineering scaffold based of nanohydroxyapatite - local rice starches

Master of Science in Biomedical Electronic Engineering

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Bibliographic Details
Main Author: Mohd Riza, Mohd Roslan
Other Authors: Nashrul Fazli, Mohd Nasir, Dr.
Format: Thesis
Language:English
Published: Universiti Malaysia Perlis (UniMAP) 2017
Subjects:
Tissue engineering
Tissue scaffolds
Hydroxyapatite
Starch
Bone tissue scaffold
Rice starch
Online Access:http://dspace.unimap.edu.my:80/xmlui/handle/123456789/78042
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spelling my.unimap-780422023-03-07T02:39:39Z Fabrication and characterization of tissue engineering scaffold based of nanohydroxyapatite - local rice starches Mohd Riza, Mohd Roslan Nashrul Fazli, Mohd Nasir, Dr. Tissue engineering Tissue scaffolds Hydroxyapatite Starch Bone tissue scaffold Rice starch Master of Science in Biomedical Electronic Engineering Bone tissue scaffold had been ventured for over the decades as a solution for bone failure and trauma. Starch is the most common natural polymer that has been used as a biomaterials and a good candidate for scaffold fabrication as there are many resources of starch in Malaysia. Native starches may contribute differently in their structure in terms of the amylose content, interactions between granules, swelling ability and solubility in which those differences can be mainly due to the botanical origin. In Malaysia itself, there are various resources of rice starches. No research yet has been performed on the application of Malaysian rice starch as a bone tissue scaffold. Balik Wangi, Bubuk Wangi, and Bario rice starches were used to fabricate the scaffold via solvent casting and salt leaching technique. These three types of rice starch originally from Sarawak, Malaysia. From the study, the porosity and the density were examined via liquid displacement test and it was found the higher the starch percentage results higher porosity percentage. Here, the dielectric properties were obtained via the values of dielectric constant and dielectric loss which are another type of indirect measurement to study the porosity of the scaffolds. The porosity has the value of dielectric constant and loss air matrix whereby this air matrix is represented by the pore in the scaffold. The morphologies and microstructures were evaluated by using Scanning Electron Microscopic (SEM) and showed the increasing pore size as increasing the starch percentage. The Young’s modulus is obtained to study the mechanical strength of the scaffolds where Balik Wangi rice starch-nHA scaffolds have the highest value of young’s modulus due to fibre content in the rice. Whereas, the interaction of the starch and hydroxyapatite blends were analyzed via Fourier Transform Infrared Spectroscopy (FTIR). Lastly, the crystallinity structure for all the rice starch-nHA scaffolds is studied via the X-Ray diffraction analysis and basically hydroxyapatite dominate the crystalinity structure of the scaffold. 2017 2023-03-07T02:39:39Z 2023-03-07T02:39:39Z Thesis http://dspace.unimap.edu.my:80/xmlui/handle/123456789/78042 en Universiti Malaysia Perlis (UniMAP) Universiti Malaysia Perlis (UniMAP) School of Mechatronic Engineering
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Tissue engineering
Tissue scaffolds
Hydroxyapatite
Starch
Bone tissue scaffold
Rice starch
spellingShingle Tissue engineering
Tissue scaffolds
Hydroxyapatite
Starch
Bone tissue scaffold
Rice starch
Mohd Riza, Mohd Roslan
Fabrication and characterization of tissue engineering scaffold based of nanohydroxyapatite - local rice starches
description Master of Science in Biomedical Electronic Engineering
author2 Nashrul Fazli, Mohd Nasir, Dr.
author_facet Nashrul Fazli, Mohd Nasir, Dr.
Mohd Riza, Mohd Roslan
format Thesis
author Mohd Riza, Mohd Roslan
author_sort Mohd Riza, Mohd Roslan
title Fabrication and characterization of tissue engineering scaffold based of nanohydroxyapatite - local rice starches
title_short Fabrication and characterization of tissue engineering scaffold based of nanohydroxyapatite - local rice starches
title_full Fabrication and characterization of tissue engineering scaffold based of nanohydroxyapatite - local rice starches
title_fullStr Fabrication and characterization of tissue engineering scaffold based of nanohydroxyapatite - local rice starches
title_full_unstemmed Fabrication and characterization of tissue engineering scaffold based of nanohydroxyapatite - local rice starches
title_sort fabrication and characterization of tissue engineering scaffold based of nanohydroxyapatite - local rice starches
publisher Universiti Malaysia Perlis (UniMAP)
publishDate 2017
url http://dspace.unimap.edu.my:80/xmlui/handle/123456789/78042
_version_ 1772813092885889024
score 13.222552

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