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In Vitro bioactivity study of thermoplastic Starch/Bentonite/Hydroxyapatite composites for biomedical applications

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Main Authors: Nurul Husna, Zakaria, Noorhafiza, Muhammad, Mohd Mustafa Al Bakri, Abdullah, S. N. F., M. Noor
Other Authors: nurulhusna.zakaria@gmail.com
Format: Article
Language:English
Published: IOP Publishing Ltd 2022
Subjects:
Potato starch
Thermoplastic
Online Access:http://dspace.unimap.edu.my:80/xmlui/handle/123456789/74704
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spelling my.unimap-747042022-03-17T03:19:45Z In Vitro bioactivity study of thermoplastic Starch/Bentonite/Hydroxyapatite composites for biomedical applications Nurul Husna, Zakaria Nurul Husna, Zakaria Noorhafiza, Muhammad Mohd Mustafa Al Bakri, Abdullah S. N. F., M. Noor nurulhusna.zakaria@gmail.com noorhafiza@unimap.edu.my mustafa_albakri@unimap.edu.my fazliah@usm.my School of Manufacturing Engineering, Universiti Malaysia Perlis (UniMAP) Center of Excellence Geopolymer and Green Technology (CEGeoGTech), School of Materials Engineering, Universiti Malaysia Perlis (UniMAP) Craniofacial and Biomaterials Sciences Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia (USM) Potato starch Thermoplastic Link to publisher's homepage at https://iopscience.iop.org/ Potato starch composites film incorporating hybrid bentonite and hydroxyapatite (HA) were investigated as novel biomaterial for potential biomedical applications. The selected potato starch/bentonite composites were prepared using different ratios of HA (1, 5 and 10 wt%) through solution casting technique. The in vitro bioactivity of potato starch composites film and neat potato starch film to be used as a control were evaluated through immersion in simulated body fluid (SBF) at 37°C for 14 days. The composites films were also subjected to characterization such as morphology, pH evaluation and biodegradability analyses following immersion in SBF. The obtained results showed that the incorporation of HA into starch/bentonite composites improves the bioactivity of the starch hybrid composites by formation of apatite layer on the surface. Increasing HA content in the composite is directly proportional to the quantity of the apatite formed on the scaffolds indicating active surface interactions between the composites and SBF. Furthermore, increasing HA content contributes also to lowering biodegradability of the composite decreases. 2022 2022-03-17T03:19:45Z 2022-03-17T03:19:45Z 2020-02 Article IOP Conference Services: Material Sciences Engineering, vol.743, 2020, 9 pages 1757-899x (online) http://dspace.unimap.edu.my:80/xmlui/handle/123456789/74704 https://doi.org/10.1088/1757-899x/743/1/012002 en IOP Publishing Ltd
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Potato starch
Thermoplastic
spellingShingle Potato starch
Thermoplastic
Nurul Husna, Zakaria
Nurul Husna, Zakaria
Noorhafiza, Muhammad
Mohd Mustafa Al Bakri, Abdullah
S. N. F., M. Noor
In Vitro bioactivity study of thermoplastic Starch/Bentonite/Hydroxyapatite composites for biomedical applications
description Link to publisher's homepage at https://iopscience.iop.org/
author2 nurulhusna.zakaria@gmail.com
author_facet nurulhusna.zakaria@gmail.com
Nurul Husna, Zakaria
Nurul Husna, Zakaria
Noorhafiza, Muhammad
Mohd Mustafa Al Bakri, Abdullah
S. N. F., M. Noor
format Article
author Nurul Husna, Zakaria
Nurul Husna, Zakaria
Noorhafiza, Muhammad
Mohd Mustafa Al Bakri, Abdullah
S. N. F., M. Noor
author_sort Nurul Husna, Zakaria
title In Vitro bioactivity study of thermoplastic Starch/Bentonite/Hydroxyapatite composites for biomedical applications
title_short In Vitro bioactivity study of thermoplastic Starch/Bentonite/Hydroxyapatite composites for biomedical applications
title_full In Vitro bioactivity study of thermoplastic Starch/Bentonite/Hydroxyapatite composites for biomedical applications
title_fullStr In Vitro bioactivity study of thermoplastic Starch/Bentonite/Hydroxyapatite composites for biomedical applications
title_full_unstemmed In Vitro bioactivity study of thermoplastic Starch/Bentonite/Hydroxyapatite composites for biomedical applications
title_sort in vitro bioactivity study of thermoplastic starch/bentonite/hydroxyapatite composites for biomedical applications
publisher IOP Publishing Ltd
publishDate 2022
url http://dspace.unimap.edu.my:80/xmlui/handle/123456789/74704
_version_ 1729704794369556480
score 13.222552

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