Histopathological changes associated with oxidative stress induced by electromagnetic waves in rats' ovarian and uterine tissues

Link to publisher's homepage at http://www.apjr.net/aboutus.asp

Saved in:
Bibliographic Details
Main Authors: Ali S.H., Alchalabi, Hasliza, Rahim, Erkihun, Aklilu, Imad I., Al-Sultan, Abd Rahman, Aziz, Mohd Fareq, Abd Malek, Suzanna, H. Ronald, Mohd Azam, Khan
Other Authors: alisaeedchalaby@yahoo.com
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020
Subjects:
Online Access:http://dspace.unimap.edu.my:80/xmlui/handle/123456789/68726
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.unimap-68726
record_format dspace
spelling my.unimap-687262020-11-16T04:23:01Z Histopathological changes associated with oxidative stress induced by electromagnetic waves in rats' ovarian and uterine tissues Ali S.H., Alchalabi Hasliza, Rahim Erkihun, Aklilu Imad I., Al-Sultan Abd Rahman, Aziz Mohd Fareq, Abd Malek Suzanna, H. Ronald Mohd Azam, Khan alisaeedchalaby@yahoo.com Histopathological changes Female sex organs Oxidative stress Electromagnetic radiation Link to publisher's homepage at http://www.apjr.net/aboutus.asp Objective To evaluate the histopathological changes in ovarian and uterine tissues associated with oxidative stress induced by electromagnetic waves. Methods Thirty female Sprague Dawley of 180 g body weight and 3 months old were used in the experimental work. Animals were divided into control and two experimental groups. Experimental groups were exposed to 1 800 MHz Global System for Mobile Communication radiofrequency radiation emitted by a signal generator for 2 h per day for 30 and 60 d, respectively. Following exposure, serum, ovaries and uteri were collected for biochemical and histopathological investigations. Results Biochemical analysis showed alterations in oxidative stress parameters in both ovaries and uteri tissues in comparison to control group. The histopathological changes were more prominent in experimental groups, in the ovary were included vacuolation in interstitial, granulosa, luteal cells and ooplasm. Other histopathological changes are disorientation of corona radiata, disruption and thinning of the zona pellucida. Cellular nucleus changes similar to fragmentation of the nucleus indicate the start of a degeneration process at Graafian follicles as well as micronuclei formation in oocyte nucleus and in some luteal cells. Histopathological changes in uterine tissue confined to increase height of luminal epithelium cells, sever apoptosis of glandular and luminal epithelium cells, and sever eosinophils, polymorphonucleocyte lymphocytes and macrophage's infiltration in myometrium and endometrium layers. Vascular congestion points out for the existence of inflammatory response changes in the endometrium. Conclusion Results executed that the potential alteration of antioxidant capacity may contribute to endometrial oxidative damage that could be related to pathogenesis and progression of endometritis. 2020-11-16T04:23:01Z 2020-11-16T04:23:01Z 2016 Article Asian Pacific Journal of Reproduction, vol.5(4), 2016, pages 301-310 2305-0500 (print) 2305-0519 (online) http://dspace.unimap.edu.my:80/xmlui/handle/123456789/68726 https://doi.org/10.1016/j.apjr.2016.06.008 en Wolters Kluwer Medknow Publications
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Histopathological changes
Female sex organs
Oxidative stress
Electromagnetic radiation
spellingShingle Histopathological changes
Female sex organs
Oxidative stress
Electromagnetic radiation
Ali S.H., Alchalabi
Hasliza, Rahim
Erkihun, Aklilu
Imad I., Al-Sultan
Abd Rahman, Aziz
Mohd Fareq, Abd Malek
Suzanna, H. Ronald
Mohd Azam, Khan
Histopathological changes associated with oxidative stress induced by electromagnetic waves in rats' ovarian and uterine tissues
description Link to publisher's homepage at http://www.apjr.net/aboutus.asp
author2 alisaeedchalaby@yahoo.com
author_facet alisaeedchalaby@yahoo.com
Ali S.H., Alchalabi
Hasliza, Rahim
Erkihun, Aklilu
Imad I., Al-Sultan
Abd Rahman, Aziz
Mohd Fareq, Abd Malek
Suzanna, H. Ronald
Mohd Azam, Khan
format Article
author Ali S.H., Alchalabi
Hasliza, Rahim
Erkihun, Aklilu
Imad I., Al-Sultan
Abd Rahman, Aziz
Mohd Fareq, Abd Malek
Suzanna, H. Ronald
Mohd Azam, Khan
author_sort Ali S.H., Alchalabi
title Histopathological changes associated with oxidative stress induced by electromagnetic waves in rats' ovarian and uterine tissues
title_short Histopathological changes associated with oxidative stress induced by electromagnetic waves in rats' ovarian and uterine tissues
title_full Histopathological changes associated with oxidative stress induced by electromagnetic waves in rats' ovarian and uterine tissues
title_fullStr Histopathological changes associated with oxidative stress induced by electromagnetic waves in rats' ovarian and uterine tissues
title_full_unstemmed Histopathological changes associated with oxidative stress induced by electromagnetic waves in rats' ovarian and uterine tissues
title_sort histopathological changes associated with oxidative stress induced by electromagnetic waves in rats' ovarian and uterine tissues
publisher Wolters Kluwer Medknow Publications
publishDate 2020
url http://dspace.unimap.edu.my:80/xmlui/handle/123456789/68726
_version_ 1698698502039666688
score 13.222552