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Evaluating the antifungal activity of Hempedu Bumi (Andrographis Paniculata) on Colletotrichum Gloeosporioides and Aspergillus Niger

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Main Author: Shangethaa, Happala Naidu
Format: Learning Object
Language:English
Published: Universiti Malaysia Perlis (UniMAP) 2016
Subjects:
Antifungal
Hempedu Bumi (Andrographis Paniculata)
Colletotrichum Gloeosporioides
Aspergillus Niger
Online Access:http://dspace.unimap.edu.my:80/xmlui/handle/123456789/42368
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spelling my.unimap-423682016-07-24T04:29:17Z Evaluating the antifungal activity of Hempedu Bumi (Andrographis Paniculata) on Colletotrichum Gloeosporioides and Aspergillus Niger Shangethaa, Happala Naidu Antifungal Hempedu Bumi (Andrographis Paniculata) Colletotrichum Gloeosporioides Aspergillus Niger Access is limited to UniMAP community. In agriculture, plant disease caused by fungi commonly affects the crops. Earlier, synthetic fungicides had been applied to inhibit the growth of fungi but eventually they resulted in resistance to some microbes. Presently, herbal plants are being introduced as natural fungicides that provide effective sources to reduce the plant disease. The purpose of this study was to determine if the herbal plant especially Andrographis paniculate exhibit antifungal properties. In order to determine antifungal properties, the A.paniculata plant leaves were extracted using different solvents such as ethanol and hexane. These extracts were screened for antifungal activity by using disc diffusion method with the usage of two fungi namely Aspergillus niger and Colletotrichum gloesoparides. The determination of antifungal activity on A.paniculata was studied by the appearance of inhibition zone around the disc of plates. In screening, ethanol solvent showed good antifungal activity when compared to hexane solvent with 11mm of inhibition zone for A.niger. The parameters that were considered for optimization include incubation time, concentration and fungi used. The best condition postulated for optimization study of ethanol plant extract are 362.74 ppm, 76.51 hours and A.niger fungus with inhibition zone of 13 mm. Therefore, this study showed that A.paniculata has a potential source of being a new antifungal agent. 2016-07-24T04:29:17Z 2016-07-24T04:29:17Z 2013-06 Learning Object http://dspace.unimap.edu.my:80/xmlui/handle/123456789/42368 en Universiti Malaysia Perlis (UniMAP) School of Bioprocess Engineering
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Antifungal
Hempedu Bumi (Andrographis Paniculata)
Colletotrichum Gloeosporioides
Aspergillus Niger
spellingShingle Antifungal
Hempedu Bumi (Andrographis Paniculata)
Colletotrichum Gloeosporioides
Aspergillus Niger
Shangethaa, Happala Naidu
Evaluating the antifungal activity of Hempedu Bumi (Andrographis Paniculata) on Colletotrichum Gloeosporioides and Aspergillus Niger
description Access is limited to UniMAP community.
format Learning Object
author Shangethaa, Happala Naidu
author_facet Shangethaa, Happala Naidu
author_sort Shangethaa, Happala Naidu
title Evaluating the antifungal activity of Hempedu Bumi (Andrographis Paniculata) on Colletotrichum Gloeosporioides and Aspergillus Niger
title_short Evaluating the antifungal activity of Hempedu Bumi (Andrographis Paniculata) on Colletotrichum Gloeosporioides and Aspergillus Niger
title_full Evaluating the antifungal activity of Hempedu Bumi (Andrographis Paniculata) on Colletotrichum Gloeosporioides and Aspergillus Niger
title_fullStr Evaluating the antifungal activity of Hempedu Bumi (Andrographis Paniculata) on Colletotrichum Gloeosporioides and Aspergillus Niger
title_full_unstemmed Evaluating the antifungal activity of Hempedu Bumi (Andrographis Paniculata) on Colletotrichum Gloeosporioides and Aspergillus Niger
title_sort evaluating the antifungal activity of hempedu bumi (andrographis paniculata) on colletotrichum gloeosporioides and aspergillus niger
publisher Universiti Malaysia Perlis (UniMAP)
publishDate 2016
url http://dspace.unimap.edu.my:80/xmlui/handle/123456789/42368
_version_ 1643799933824794624
score 13.226497

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