Staff View: Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways

Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways

Ferulic acid metabolism was studied in cultures of the white-rot fungus Pycnoporus cinnabarinus I-937. After 6 days of growth, during the secondary metabolism of the fungus, the concentration of vanillin in the culture medium reached a maximum of 64 mg l−1, corresponding to a molar yield of 27.5%. D...

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Main Authors:	Falconnier, B., Lapierre, C., Lesage-Meessen, L., Yonnet, G., Brunerie, P., Colonna-Ceccaldi, B., Corrieu, G., Asther, M.
Format:	Article
Language:	English
Published:	Elsevier Science B.V. 2008
Subjects:	Vanillin. Metabolism, Secondary.
Online Access:	http://dspace.unimap.edu.my/xmlui/handle/123456789/1501
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id	my.unimap-1501
record_format	dspace
spelling	my.unimap-15012008-08-05T03:37:03Z Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways Falconnier, B. Lapierre, C. Lesage-Meessen, L. Yonnet, G. Brunerie, P. Colonna-Ceccaldi, B. Corrieu, G. Asther, M. Vanillin. Metabolism, Secondary. Ferulic acid metabolism was studied in cultures of the white-rot fungus Pycnoporus cinnabarinus I-937. After 6 days of growth, during the secondary metabolism of the fungus, the concentration of vanillin in the culture medium reached a maximum of 64 mg l−1, corresponding to a molar yield of 27.5%. During the biotransformation process, the propenoic side chain of ferulic acid was oxidatively cleaved to yield vanillic acid, further decarboxylated to 2-methoxyhydroquinone. In addition, two reductive routes were evidenced, involving the conversion of ferulic and vanillic acids into coniferyl and vanillyl alcohols, respectively. The biotransformation process was not easily controlled since the P. cinnabarinus species is known to release laccase into the growth medium. When produced, the enzyme countered the vanillin formation by promoting the polymerization of ferulic acid into lignin-like polymers. 2008-08-05T03:37:03Z 2008-08-05T03:37:03Z 1994 Article Journal of Biotechnology, vol. 37, no. 2, pages 123-132 01681656 http://hdl.handle.net/123456789/1501 en Elsevier Science B.V.
institution	Universiti Malaysia Perlis
building	UniMAP Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Perlis
content_source	UniMAP Library Digital Repository
url_provider	http://dspace.unimap.edu.my/
language	English
topic	Vanillin. Metabolism, Secondary.
spellingShingle	Vanillin. Metabolism, Secondary. Falconnier, B. Lapierre, C. Lesage-Meessen, L. Yonnet, G. Brunerie, P. Colonna-Ceccaldi, B. Corrieu, G. Asther, M. Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways
description	Ferulic acid metabolism was studied in cultures of the white-rot fungus Pycnoporus cinnabarinus I-937. After 6 days of growth, during the secondary metabolism of the fungus, the concentration of vanillin in the culture medium reached a maximum of 64 mg l−1, corresponding to a molar yield of 27.5%. During the biotransformation process, the propenoic side chain of ferulic acid was oxidatively cleaved to yield vanillic acid, further decarboxylated to 2-methoxyhydroquinone. In addition, two reductive routes were evidenced, involving the conversion of ferulic and vanillic acids into coniferyl and vanillyl alcohols, respectively. The biotransformation process was not easily controlled since the P. cinnabarinus species is known to release laccase into the growth medium. When produced, the enzyme countered the vanillin formation by promoting the polymerization of ferulic acid into lignin-like polymers.
format	Article
author	Falconnier, B. Lapierre, C. Lesage-Meessen, L. Yonnet, G. Brunerie, P. Colonna-Ceccaldi, B. Corrieu, G. Asther, M.
author_facet	Falconnier, B. Lapierre, C. Lesage-Meessen, L. Yonnet, G. Brunerie, P. Colonna-Ceccaldi, B. Corrieu, G. Asther, M.
author_sort	Falconnier, B.
title	Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways
title_short	Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways
title_full	Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways
title_fullStr	Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways
title_full_unstemmed	Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways
title_sort	vanillin as a product of ferulic acid biotransformation by the white-rot fungus pycnoporus cinnabarinus i-937: identification of metabolic pathways
publisher	Elsevier Science B.V.
publishDate	2008
url	http://dspace.unimap.edu.my/xmlui/handle/123456789/1501
_version_	1643787357316448256
score	13.222552

Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: identification of metabolic pathways

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