Cover Image

A Review On Heliotropium Indicum L. (Boraginaceae)

Heliotropium indicum Linn., commonly known as ‘Indian heliotrope’ is very common in India with a long history of traditional medicinal uses in many countries in the world. The plant is reported to possess antibacterial, antitumor, uterine stimulant effect, antifertility, wound healing, anti-inflamma...

Full description

Saved in:
Bibliographic Details
Main Authors: Dash, G. K., Abdullah, M. S., UniKL RCMP, Faculty of Pharmacy and Health Sciences
Format: Article
Language:English
Published: IJPSR (International Journal of Pharmaceutical Sciences and Research) 2015
Subjects:
Heliotropium indicum Linn
Traditional
Pyrrolizidine alkaloids
Bioactivity
Pharmacognosy
Online Access:http://localhost/xmlui/handle/123456789/9391
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.unikl.ir-9391
record_format eprints
spelling my.unikl.ir-93912015-03-27T01:36:35Z A Review On Heliotropium Indicum L. (Boraginaceae) Dash, G. K. Abdullah, M. S. UniKL RCMP, Faculty of Pharmacy and Health Sciences Heliotropium indicum Linn Traditional Pyrrolizidine alkaloids Bioactivity Pharmacognosy Heliotropium indicum Linn., commonly known as ‘Indian heliotrope’ is very common in India with a long history of traditional medicinal uses in many countries in the world. The plant is reported to possess antibacterial, antitumor, uterine stimulant effect, antifertility, wound healing, anti-inflammatory, antinociceptive and diuretic activities. Several pyrrolizidine alkaloids have been isolated from this species. The active principle Indicine-N-oxide has reached Phase 1 clinical trials in advanced cancer patients. But severe toxic side-effects showed that a therapy with indicine-N-oxide was not justified. Most of the alkaloids are hepatoxic and therefore internal use of Heliotropium species is not recommended. External application to promote wound healing and to fight infections seems to be less hazardous, but more research is needed. The comprehensive account of the chemical constituents and the biological activities are presented in this review such that the potential use of this plant in various traditional medicines can be systematically evaluated. 2015-03-02T02:46:54Z 2015-03-02T02:46:54Z 2013 Article Image A Review On Helitropium Indicum L. (Boraginaceae), (2013). International Journal of Pharmceutical Sciences), 4(4), 1253-1258. Retrieved from ijpsr.com/?action=download_pdf&postid=6859 0975-8232 http://localhost/xmlui/handle/123456789/9391 en IJPSR (International Journal of Pharmaceutical Sciences and Research)
institution Universiti Kuala Lumpur
building UniKL Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kuala Lumpur
content_source UniKL Institutional Repository
url_provider http://ir.unikl.edu.my/
language English
topic Heliotropium indicum Linn
Traditional
Pyrrolizidine alkaloids
Bioactivity
Pharmacognosy
spellingShingle Heliotropium indicum Linn
Traditional
Pyrrolizidine alkaloids
Bioactivity
Pharmacognosy
Dash, G. K.
Abdullah, M. S.
UniKL RCMP, Faculty of Pharmacy and Health Sciences
A Review On Heliotropium Indicum L. (Boraginaceae)
description Heliotropium indicum Linn., commonly known as ‘Indian heliotrope’ is very common in India with a long history of traditional medicinal uses in many countries in the world. The plant is reported to possess antibacterial, antitumor, uterine stimulant effect, antifertility, wound healing, anti-inflammatory, antinociceptive and diuretic activities. Several pyrrolizidine alkaloids have been isolated from this species. The active principle Indicine-N-oxide has reached Phase 1 clinical trials in advanced cancer patients. But severe toxic side-effects showed that a therapy with indicine-N-oxide was not justified. Most of the alkaloids are hepatoxic and therefore internal use of Heliotropium species is not recommended. External application to promote wound healing and to fight infections seems to be less hazardous, but more research is needed. The comprehensive account of the chemical constituents and the biological activities are presented in this review such that the potential use of this plant in various traditional medicines can be systematically evaluated.
format Article
author Dash, G. K.
Abdullah, M. S.
UniKL RCMP, Faculty of Pharmacy and Health Sciences
author_facet Dash, G. K.
Abdullah, M. S.
UniKL RCMP, Faculty of Pharmacy and Health Sciences
author_sort Dash, G. K.
title A Review On Heliotropium Indicum L. (Boraginaceae)
title_short A Review On Heliotropium Indicum L. (Boraginaceae)
title_full A Review On Heliotropium Indicum L. (Boraginaceae)
title_fullStr A Review On Heliotropium Indicum L. (Boraginaceae)
title_full_unstemmed A Review On Heliotropium Indicum L. (Boraginaceae)
title_sort review on heliotropium indicum l. (boraginaceae)
publisher IJPSR (International Journal of Pharmaceutical Sciences and Research)
publishDate 2015
url http://localhost/xmlui/handle/123456789/9391
_version_ 1644485101078183936
score 13.211869

Similar Items