Effects of honey on factors relating to cardiovascular disease based on in vitro and in vivo studies
Along history, honey has been used not only as a nutrient, but also as a medicine. Honey is rich in phenolic compounds, which act as natural antioxidants and are increasingly popular due to their potential in improving the human health. Thus, this study was designed to analyse some physico-chemic...
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| Format: | Thesis |
| Language: | English |
| Published: |
Universiti Malaysia Terengganu
2022
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| Online Access: | http://umt-ir.umt.edu.my:8080/handle/123456789/17143 |
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| Summary: | Along history, honey has been used not only as a nutrient, but also as a medicine.
Honey is rich in phenolic compounds, which act as natural antioxidants and are
increasingly popular due to their potential in improving the human health. Thus, this
study was designed to analyse some physico-chemical characteristics of two different
types of honey, namely honey bee honey (Acacia) and stingless bee honey (Kelulut),
to study the anti-inflammatory effects of polyphenols on the atherosclerosis
modulation in human umbilical vein endothelial cells (HUVECs) and investigate the
effects of these two honey for supplementation in subjects with cardiovascular risk
factor. Ash, colour, water activity, viscosity, Brix, moisture, acidity, hidroxymethyl
furfural (HMF), diastase activity and sugar analyses of the honey samples were
assessed for chemical characterisation. Total phenolic compound, ferric reducing
antioxidant capacity (FRAP) and 2, 2-diphenyl-1-picryhydrazyl (DPPH) free radical
scavenging activity were measured as antioxidant determinants. Acacia honey in this
study showed significantly higher content of colour (redness and yellowness),
viscosity, Brix, sugar content, FRAP and total phenolic compared to those of Kelulut
honey. The results also showed that Acacia honey had significantly lower content of
water activity, moisture, acidity, HMF and diastase activity as compared to Kelulut
honey. |
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