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Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP

Acanthamoeba is a free-living amoeba but pathogenic to humans, causing a potentially blinding infection of the cornea(keratitis). Keratitis is an important public health problem developing country. Therefore, research on new drugs for the treatment of this infection is still constitutes an importan...

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Main Author: Ida Muryany Md Yasin
Format: Thesis
Language:English
Published: Fakulti Sains dan Teknologi 2011
Subjects:
QL 368 .A5 I3 2008
Ida Muryany Md Yasin
Tesis FST 2008
Communicable diseases
Acanthamoeba
Online Access:http://hdl.handle.net/123456789/1002
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spelling my.umt.ir-10022016-03-11T22:09:47Z Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP Ida Muryany Md Yasin QL 368 .A5 I3 2008 Ida Muryany Md Yasin Tesis FST 2008 Communicable diseases Acanthamoeba Acanthamoeba is a free-living amoeba but pathogenic to humans, causing a potentially blinding infection of the cornea(keratitis). Keratitis is an important public health problem developing country. Therefore, research on new drugs for the treatment of this infection is still constitutes an important therapeutic demand. The objective of this study were determined the cytotoxic and genotoxic effects of crude extracts of sponges from Aaptos sp., Xestospongia sp. and Halicondria sp. collected from Kapas, Perhentian and Redang Islands, Terengganu on trophozoites of two clinical isolates namely Acanthamoeba castellanii (IMR isolate) and Acanthamoeba sp. (HKL isolate) and one free-living amoeba, Acanthamoeba polyphaga strain 1501/3A (but potential of being pathogenic). 2011-11-22T02:19:04Z 2011-11-22T02:19:04Z 2008-05 Thesis http://hdl.handle.net/123456789/1002 en ;QL 368 .A5 I3 2008 application/pdf application/pdf Fakulti Sains dan Teknologi
institution Universiti Malaysia Terengganu
building Perpustakaan Sultanah Nur Zahirah
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Terengganu
content_source UMT-IR
url_provider http://umt-ir.umt.edu.my:8080/
language English
topic QL 368 .A5 I3 2008
Ida Muryany Md Yasin
Tesis FST 2008
Communicable diseases
Acanthamoeba
spellingShingle QL 368 .A5 I3 2008
Ida Muryany Md Yasin
Tesis FST 2008
Communicable diseases
Acanthamoeba
Ida Muryany Md Yasin
Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
description Acanthamoeba is a free-living amoeba but pathogenic to humans, causing a potentially blinding infection of the cornea(keratitis). Keratitis is an important public health problem developing country. Therefore, research on new drugs for the treatment of this infection is still constitutes an important therapeutic demand. The objective of this study were determined the cytotoxic and genotoxic effects of crude extracts of sponges from Aaptos sp., Xestospongia sp. and Halicondria sp. collected from Kapas, Perhentian and Redang Islands, Terengganu on trophozoites of two clinical isolates namely Acanthamoeba castellanii (IMR isolate) and Acanthamoeba sp. (HKL isolate) and one free-living amoeba, Acanthamoeba polyphaga strain 1501/3A (but potential of being pathogenic).
format Thesis
author Ida Muryany Md Yasin
author_facet Ida Muryany Md Yasin
author_sort Ida Muryany Md Yasin
title Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_short Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_full Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_fullStr Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_full_unstemmed Cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from Terengganu Island on Acanthamoeba SPP
title_sort cytotoxic and genotoxic effects of methanolic crude extracts from selected marine sponges collected from terengganu island on acanthamoeba spp
publisher Fakulti Sains dan Teknologi
publishDate 2011
url http://hdl.handle.net/123456789/1002
_version_ 1738395550045175808
score 13.222552

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