Exploring novel pyridine carboxamide derivatives as urease inhibitors: synthesis, molecular docking, kinetic studies and ADME profile
The rapid development of resistance by ureolytic bacteria which are involved in various life-threatening conditions such as gastric and duodenal cancer has induced the need to develop a new line of therapy which has anti-urease activity. A series of pyridine carboxamide and carbothioamide derivative...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute
2022
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| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/42524/1/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/42524/ https://doi.org/10.3390/ph15101288 |
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